Search Results - "Wenxiang Hu"

The hepatocyte clock and feeding control chronophysiology of multiple liver cell types by Guan, Dongyin, Xiong, Ying, Trinh, Trang Minh, Xiao, Yang, Hu, Wenxiang, Jiang, Chunjie, Dierickx, Pieterjan, Jang, Cholsoon, Rabinowitz, Joshua D, Lazar, Mitchell A

“…Most cells of the body contain molecular clocks, but the requirement of peripheral clocks for rhythmicity and their effects on physiology are not well…”
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Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes by Guan, Dongyin, Xiong, Ying, Borck, Patricia C., Jang, Cholsoon, Doulias, Paschalis-Thomas, Papazyan, Romeo, Fang, Bin, Jiang, Chunjie, Zhang, Yuxiang, Briggs, Erika R., Hu, Wenxiang, Steger, David, Ischiropoulos, Harry, Rabinowitz, Joshua D., Lazar, Mitchell A.

“…Overnutrition disrupts circadian metabolic rhythms by mechanisms that are not well understood. Here, we show that diet-induced obesity (DIO) causes massive…”
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Molecular and cellular regulation of thermogenic fat by Wang, Cuihua, Wang, Xianju, Hu, Wenxiang

“…Thermogenic fat, consisting of brown and beige adipocytes, dissipates energy in the form of heat, in contrast to the characteristics of white adipocytes that…”
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Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

“…Neural progenitor cells （NPCs） can be induced from somatic cells by defined factors. Here we report that NPCs can be generated from mouse embryonic fibroblasts…”
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Direct conversion of astrocytes into neuronal cells by drug cocktail by Cheng, Lin, Gao, Longfei, Guan, Wuqiang, Mao, Jianxin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Pei, Gang

“…Dear Editor, Neurological disorder is one of the greatest threats to public health according to the World Health Organi- zation. Because neurons have little or…”
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Activation of Aryl Hydrocarbon Receptor (AhR) by Tranilast, an Anti-allergy Drug, Promotes miR-302 Expression and Cell Reprogramming by Hu, Wenxiang, Zhao, Jian, Pei, Gang

“…MiR-302 has been shown to regulate pluripotency genes and help somatic cell reprogramming. Thus, promotion of endogenous miR-302 expression could be a…”
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The Mechanism of Lipopolysaccharide's Effect on Secretion of Endometrial Mucins in Female Mice during Pregnancy by Lu, Dezhang, Hu, Wenxiang, Tian, Tian, Wang, Mengran, Zhou, Mengru, Wu, Chenchen

“…The main toxic component of endotoxins released from the death or dissolution of Gram-negative bacteria is lipopolysaccharide (LPS), which exists widely in the…”
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Hepatocyte SREBP signaling mediates clock communication within the liver by Guan, Dongyin, Bae, Hosung, Zhou, Dishu, Chen, Ying, Jiang, Chunjie, La, Cam Mong, Xiao, Yang, Zhu, Kun, Hu, Wenxiang, Trinh, Trang Minh, Liu, Panpan, Xiong, Ying, Cai, Bishuang, Jang, Cholsoon, Lazar, Mitchell A

“…Rhythmic intraorgan communication coordinates environmental signals and the cell-intrinsic clock to maintain organ homeostasis. Hepatocyte-specific KO of core…”
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Endotoxins Induced ECM-Receptor Interaction Pathway Signal Effect on the Function of MUC2 in Caco2/HT29 Co-Culture Cells by Hu, Wenxiang, Feng, Ping, Zhang, Mingming, Tian, Tian, Wang, Shengxiang, Zhao, Baoyu, Li, Yajie, Wang, Shuo, Wu, Chenchen

“…Endotoxins are toxic substances that widely exist in the environment and can enter the intestine with food and other substances. Intestinal epithelial cells…”
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Editorial: Novel insights into the pathophysiology of diabetes-related complications: Implications for improved therapeutic strategies by Ma, Jian, Jiang, Chunjie, Fu, Xuebin, Chen, Jun, Hu, Wenxiang, Yuan, Lin

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An Empirical Comparison of Compiler Testing Techniques by Junjie Chen, Wenxiang Hu, Dan Hao, Yingfei Xiong, Hongyu Zhang, Lu Zhang, Bing Xie

“…Compilers, as one of the most important infrastructure of today's digital world, are expected to be trustworthy. Different testing techniques are developed for…”
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Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

“…In the initial published version of this article, an er- ror was made during the assembly of Figure 6C. Figure 6C displays representative images of morphology…”
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Synthesis of 9-Substituted Berberine Derivatives with Microwave Irradiation by Han, Xie, Shao, Kaiyuan, Hu, Wenxiang

“…Hyperglycemia is frequently accompanying with hyperlipidemia. To explore the potent drugs with dual-activity and dual-site effects that could reduce blood…”
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Research on Chemical Reactivity of Nitrotriazolam in Its Process of Preparation by Yang, Bowen, An, Qiufeng, Zhao, Zhigang, Shao, Kaiyuan, Hu, Wenxiang

“…Chemical reaction possibility was described quantitatively for the case of nitrotriazolam preparation with 2-clonazepam by using the data of two quantum…”
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Erratum: Generation of neural progenitor cells by chemical cocktails and hypoxia by Cheng, Lin, Hu, Wenxiang, Qiu, Binlong, Zhao, Jian, Yu, Yongchun, Guan, Wuqiang, Wang, Min, Yang, Wuzhou, Pei, Gang

“…Correction to: Cell Research (2014) 24:665–679. doi:10.1038/cr.2014.32; published online on 18 March 2014 In the initial published version of this article, an…”
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Lewis Acid Catalyzed Cyclization of Glycals/2-Deoxy-d-ribose with Arylamines: Additional Findings on Product Structure and Reaction Diastereoselectivity by Du, Chengtang, Li, Fulong, Zhang, Xuefeng, Hu, Wenxiang, Yao, Qizheng, Zhang, Ao

“…The cyclization reactions of arylamines with 2-deoxy-d-ribose or glycals were reinvestigated in the current report. In the montmorillonite KSF- or…”
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Studies on the Activities of Electrophilic Sites on Benzene Ring of 4-Substituted Anilines and Their Acyl Compounds with Multiphilicity Descriptor by Shen, Xizhou, He, Huajun, Yang, Bowen, Zhao, Zhigang, Shao, Kaiyuan, Hu, Wenxiang

“…In this paper, the activities of electrophilic sites on benzene ring of 4-substituted anilines and their acyl compounds were studied with the quantitative…”
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Synthesis Study on Marmycin A: Preparation of the C3′-Desmethyl Analogues by Ding, Chunyong, Tu, Shanghui, Li, Fuying, Wang, Yuanxiang, Yao, Qizheng, Hu, Wenxiang, Xie, Hua, Meng, Linghua, Zhang, Ao

“…Total synthesis of natural product marmycin A was studied. An expeditious synthetic strategy for the key fragment 8-amino-3-methylbenz[a]anthraquinone (1) was…”
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Pharmacophore Screening on Piperidinecarboxamides Derivatives Based on GALAHAD and CoMFA Models by Liu, Ming Wu, Qiangsan Hu, Wenxiang

“…In order to discover the novel anticonvulsant drugs, pharmacophore screening of the anticonvulsant inhibitors was enforced. Genetic Algorithm with Linear…”
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Design, synthesis and biological evaluation of novel acrylamide analogues as inhibitors of BCR–ABL kinase by Li, Shuxin, Yao, Zhenglin, Zhao, Yanjin, Chen, Wei, Wang, Huijia, Kuang, Xianzhao, Zhan, Wenhu, Yao, Shan, Yu, Shanyou, Hu, Wenxiang

“…Novel acrylamide derivatives were synthesized and evaluated using ABL kinase and K562 cells. Introduction of trifluoromethyl group at R1 or R2 was able to…”
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