Search Results - "Wentland, JoAnn"

Biodistribution and Targeting of Anti-5T4 Antibody-Drug Conjugate Using Fluorescence Molecular Tomography by Giddabasappa, Anand, Gupta, Vijay R, Norberg, Rand, Gupta, Parul, Spilker, Mary E, Wentland, Joann, Rago, Brian, Eswaraka, Jeetendra, Leal, Mauricio, Sapra, Puja

“…Understanding a drug's whole-body biodistribution and tumor targeting can provide important information regarding efficacy, safety, and dosing parameters…”
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Preclinical Development of an anti-5T4 Antibody–Drug Conjugate: Pharmacokinetics in Mice, Rats, and NHP and Tumor/Tissue Distribution in Mice by Leal, Mauricio, Wentland, JoAnn, Han, Xiaogang, Zhang, Yanhua, Rago, Brian, Duriga, Nicole, Spriggs, Franklin, Kadar, Eugene, Song, Wei, McNally, James, Shakey, Quazi, Lorello, Leslie, Lucas, Judy, Sapra, Puja

“…The pharmacokinetics of an antibody (huA1)–drug (auristatin microtubule disrupting MMAF) conjugate, targeting 5T4-expressing cells, were characterized during…”
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Abstract 4293: Whole-body bio-distribution of anti-5T4-mcMMAF (anti-5T4-ADC) using fluorescence molecular tomography (FMT) imaging in a non-small cell lung cancer mice model by Giddabasappa, Anand, Norberg, Rand, Leal, Mauricio, Paterson, David, Lalwani, Kush, Levkoff, Ted, Rapa, Stella, Sapra, Puja, Ritche, Michael, Wentland, Joann, Rago, Brian, Eswaraka, Jeetendra

“…Abstract Introduction: Currently bio-distribution of biologic drugs is evaluated by PET imaging, autoradioraphy using radio-labeled molecules or ex vivo…”
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Abstract C117: Preclinical pharmacokinetics of an antibody-drug conjugate targeting 5T4 by Leal, Mauricio, Wentland, Joann, Clark, Tracey, Zhang, Jenny, Marcek, John, Khandke, Kiran, DiJoseph, John, Lucas, Judy, Groeber, Elizabeth, Han, Xiaognag, Hu, George, Gerber, Hans-Peter, Sapra, Puja

“…Abstract The pharmacokinetics of a novel antibody (huA1)-drug (auristatin tubulin inhibitor MMAF) conjugate, targeting 5T4-expressing cells, were obtained in…”
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