Search Results - "Wenske, Britta"
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Anti-CSF-1 treatment is effective to prevent carcinoma invasion induced by monocyte-derived cells but scarcely by microglia
Published in Oncotarget (20-06-2015)“…The mononuclear phagocytic system is categorized in three major groups: monocyte-derived cells (MCs), dendritic cells and resident macrophages. During breast…”
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Zebrafish disease model of human RNASET2-deficient cystic leukoencephalopathy displays abnormalities in early microglia
Published in Biology open (07-05-2020)“…Human infantile-onset RNASET2-deficient cystic leukoencephalopathy is a Mendelian mimic of cytomegalovirus brain infection with prenatally developing…”
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Investigation of Cell-Contact Dependent Alterations in Immune Synapse Formation between T Cells and BCP-ALL Cells
Published in Blood (13-11-2019)“…Cancer-development is often associated with a state of immune attenuation and impaired antigen-recognition, contributing to the failure of immune surveillance…”
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Intralesional TLR4 agonist treatment strengthens the organ defense against colonizing cancer cells in the brain
Published in Oncogene (11-11-2022)“…Brain metastasis in breast cancer remains difficult to treat and its incidence is increasing. Therefore, the development of new therapies is of utmost clinical…”
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LEF1 supports metastatic brain colonization by regulating glutathione metabolism and increasing ROS resistance in breast cancer
Published in International journal of cancer (01-06-2020)“…More than half of all brain metastases show infiltrating rather than displacing growth at the macro‐metastasis/organ parenchyma interface (MMPI), a finding…”
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Zebrafish disease model of human RNASET2 deficient cystic leukoencephalopathy displays abnormalities in early microglia
Published in Biology open (01-01-2020)“…Human infantile-onset RNASET2 deficient cystic leukoencephalopathy is a Mendelian mimic of in utero cytomegalovirus brain infection with prenatally developing…”
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Journal Article