Search Results - "Wenqing Cai"
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1
Dissecting super-enhancer hierarchy based on chromatin interactions
Published in Nature communications (05-03-2018)“…Recent studies have highlighted super-enhancers (SEs) as important regulatory elements for gene expression, but their intrinsic properties remain incompletely…”
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2
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart
Published in Nature (London) (24-09-2015)“…The elucidation of factors that activate the regeneration of the adult mammalian heart is of major scientific and therapeutic importance. Here we found that…”
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3
Nonlinear dynamic separation characteristics of friction pair and experimental analysis
Published in Scientific reports (16-04-2024)“…This paper aims to reduce friction pair erosion of the clutch in the case of continuous shift; the dynamic separation process of the friction pair is…”
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4
Small molecule inhibitors of mammalian thioredoxin reductase
Published in Free radical biology & medicine (15-01-2012)“…Mammalian thioredoxin reductases (TrxRs) are a family of NADPH-dependent flavoproteins with a penultimate selenocysteine residue at the carboxy-terminus…”
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5
The Simulation and Parameter Optimization of the Hole-Forming Process of a Duckbilled Hole-Forming Device
Published in Agriculture (Basel) (01-06-2024)“…This paper addresses the hole-forming process of a duckbilled hole-forming device. Based on a coupled simulation using the multi-body dynamics software…”
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6
Small molecule regulators of autophagy identified by an image-based high-throughput screen
Published in Proceedings of the National Academy of Sciences - PNAS (27-11-2007)“…Autophagy is a lysosome-dependent cellular catabolic mechanism mediating the turnover of intracellular organelles and long-lived proteins. Reduction of…”
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7
Synergistic effect between CeO2 and Cu for ethylene carbonate hydrogenation
Published in Journal of porous materials (01-12-2022)“…Cu–CeO 2 /C composite catalysts with porous structure were prepared by a microwave-assisted carbonization–impregnation method, which demonstrated a significant…”
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8
Mapping the evolving landscape of super-enhancers during cell differentiation
Published in Genome Biology (15-09-2021)“…Super-enhancers are clusters of enhancer elements that play critical roles in the maintenance of cell identity. Current investigations on super-enhancers are…”
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9
Image-Aided Analysis of Ballast Particle Movement Along a High-Speed Railway
Published in Engineering (Beijing, China) (01-08-2023)“…•Image-aided technique precisely captured ballast movement of high-speed railway.•Ballast particle flow was greatly amplified under high-speed train…”
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10
Curcumin targeting the thioredoxin system elevates oxidative stress in HeLa cells
Published in Toxicology and applied pharmacology (01-08-2012)“…The thioredoxin system, composed of thioredoxin reductase (TrxR), thioredoxin (Trx), and NADPH, is ubiquitous in all cells and involved in many redox-dependent…”
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11
Small Molecule-Mediated TGF-β Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells
Published in Cell stem cell (03-08-2012)“…The cellular signals controlling the formation of cardiomyocytes, vascular smooth muscle, and endothelial cells from stem cell-derived mesoderm are poorly…”
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12
The Study on the Substrate Effect in the Nanoindentation Experiment of the Hybrid Material
Published in Advances in civil engineering (04-01-2022)“…The nanoindentation (NI) experiment is an effective method to evaluate the micromechanical property of materials. The substrate effect is a nonnegligible…”
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13
Research on the Control Strategy of the Power Shift System of a Cotton Picker Based on a Fuzzy Algorithm
Published in Agriculture (Basel) (01-06-2024)“…The control strategy of a power shift system has a significant impact on the driving stability and comfort of cotton pickers. To prevent the cotton picker from…”
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14
Systematic Structure-Activity Relationship (SAR) Exploration of Diarylmethane Backbone and Discovery of A Highly Potent Novel Uric Acid Transporter 1 (URAT1) Inhibitor
Published in Molecules (Basel, Switzerland) (27-01-2018)“…In order to systematically explore and better understand the structure-activity relationship (SAR) of a diarylmethane backbone in the design of potent uric…”
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15
Enabling the Electrochemical Performance of Maricite-NaMnPO4 and Maricite-NaFePO4 Cathode Materials in Sodium-Ion Batteries
Published in International journal of electrochemistry (27-01-2023)“…NaMnPO4 and NaFePO4, polyanion cathode materials, exist in two different phases maricite/natrophilite and maricite/olivine, respectively. Both natrophilite…”
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16
Transmission Characteristics and Experiment of Hydraulic–Mechanical Transmission of Cotton Picker
Published in Agriculture (Basel) (01-08-2024)“…To overcome the issue of unstable speed output encountered by cotton pickers operating in harsh environments and subject to frequent external load…”
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17
Optimisation of Control Strategies for Power Shift Gearboxes
Published in Agriculture (Basel) (01-06-2023)“…This study is based on the influence of power shift control on the smoothness of cotton picker shifts and proposes an optimization method for the smoothness of…”
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18
A Nodal-to-TGFβ Cascade Exerts Biphasic Control Over Cardiopoiesis
Published in Circulation research (14-09-2012)“…RATIONALE:The transforming growth factor-β (TGFβ) family member Nodal promotes cardiogenesis, but the mechanism is unclear despite the relevance of TGFβ family…”
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19
Design of Hydrostatic Power Shift Compound Drive System for Cotton Picker Experiment
Published in Agriculture (Basel) (01-08-2023)“…To meet the working performance demand of cotton pickers, a hydrostatic power shift composite drive system design is proposed. This study aims to enhance the…”
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20
Design of SGLT2 Inhibitors for the Treatment of Type 2 Diabetes: A History Driven by Biology to Chemistry
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01-01-2015)“…A brief history of the design of sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors is reviewed. The design of O-glucoside SGLT2 inhibitors by…”
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