Search Results - "Wenning, Anna S."
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T cell activation requires mitochondrial translocation to the immunological synapse
Published in Proceedings of the National Academy of Sciences - PNAS (04-09-2007)“…T helper (Th) cell activation is required for the adaptive immune response. Formation of the immunological synapse (IS) between Th cells and antigen-presenting…”
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Spatial Heterogeneity of Immune Regulators Drives Dynamic Changes in Local Immune Responses, Affecting Disease Outcomes in Pancreatic Cancer
Published in Clinical cancer research (13-09-2024)“…Pancreatic ductal adenocarcinoma (PDAC) is considered a low-immunogenic (LI) tumor with a "cold" tumor microenvironment and is mostly unresponsive to immune…”
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Calcium dependence of T cell proliferation following focal stimulation
Published in European journal of immunology (01-10-2007)“…Clonal T cell expansion through proliferation is a central process of the adaptive immune response. Apoptosis of activated T cells is required to avoid chronic…”
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TRP expression pattern and the functional importance of TRPC3 in primary human T-cells
Published in Biochimica et biophysica acta (01-03-2011)“…TRP proteins form ion channels which are activated following receptor stimulation. In T-cell lines, expression data of TRP proteins have been published…”
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MCL1 Is Required for Maintenance of Intestinal Homeostasis and Prevention of Carcinogenesis in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2020)“…Intestinal epithelial homeostasis depends on a tightly regulated balance between intestinal epithelial cell (IEC) death and proliferation. While the disruption…”
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Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry
Published in Immunology (2010)“…Costimulation is a fundamental principle of T-cell activation. In addition to T-cell receptor engagement, the interaction between CD80 and/or CD86 with CD28…”
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Perioperative Fully Closed-loop versus Usual Care Glucose Management in Adults Undergoing Major Abdominal Surgery - A Two-centre Randomised Controlled Trial
Published in Annals of surgery (30-09-2024)“…To assess the efficacy and safety of fully closed-loop (FCL) compared with usual care (UC) glucose control in patients experiencing major abdominal…”
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Pneumothorax and Subclavian Vein Thrombosis in Patients With Venous Access Device Implantation
Published in International surgery (01-07-2017)“…The primary aim is to assess the length of hospitalization due to iatrogenic pneumothorax as a main complication of totally implantable venous access device…”
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