Search Results - "Wennagel, Doris"
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Huntington's disease alters human neurodevelopment
Published in Science (American Association for the Advancement of Science) (14-08-2020)“…Although Huntington's disease is a late-manifesting neurodegenerative disorder, both mouse studies and neuroimaging studies of presymptomatic mutation carriers…”
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Treating early transient neuronal defects in a mouse model of Huntington's disease delays the signs of the disease in adulthood
Published in M.S. Médecine sciences (01-04-2023)Get more information
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Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton
Published in Cell reports (Cambridge) (30-08-2022)“…Compelling evidence indicates that in Huntington’s disease (HD), mutation of huntingtin (HTT) alters several aspects of early brain development such as…”
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Treating early postnatal circuit defect delays Huntington's disease onset and pathology in mice
Published in Science (American Association for the Advancement of Science) (23-09-2022)“…Recent evidence has shown that even mild mutations in the Huntingtin gene that are associated with late-onset Huntington's disease (HD) disrupt various aspects…”
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GluD1 binds GABA and controls inhibitory plasticity
Published in Science (American Association for the Advancement of Science) (22-12-2023)“…Fast synaptic neurotransmission in the vertebrate central nervous system relies primarily on ionotropic glutamate receptors (iGluRs), which drive neuronal…”
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