Search Results - "Wenger, D"
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Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology
Published in Nature neuroscience (01-11-2021)“…Amyotrophic lateral sclerosis overlapping with frontotemporal dementia (ALS/FTD) is a fatal and currently untreatable disease characterized by rapid cognitive…”
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Cerebral organoids at the air–liquid interface generate diverse nerve tracts with functional output
Published in Nature neuroscience (01-04-2019)“…Neural organoids have the potential to improve our understanding of human brain development and neurological disorders. However, it remains to be seen whether…”
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A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
Published in Molecular systems biology (19-07-2011)“…The transcriptome and proteome change dynamically as cells respond to environmental stress; however, prior proteomic studies reported poor correlation between…”
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Imaging features of intraosseous hemangiomas: beyond the mobile spine and calvarium
Published in Skeletal radiology (01-09-2023)“…Objective Describe imaging features of intraosseous hemangiomas located outside of the mobile spine and calvarium. Materials and Methods Imaging and medical…”
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Proteomic and phosphoproteomic comparison of human ES and iPS cells
Published in Nature methods (01-10-2011)“…A comparison of the proteomes and phosphoproteomes of four human embryonic stem cell lines and four induced pluripotent stem cell lines is reported, revealing…”
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Health risk associated with residential relocation among people who inject drugs in Los Angeles and San Francisco, CA: a cross sectional study
Published in BMC public health (25-04-2022)“…Given the housing instability and frequent residential relocation (both volitional and hegemonic) of people who inject drugs, we sought to determine whether…”
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Human embryonic stem cell phosphoproteome revealed by electron transfer dissociation tandem mass spectrometry
Published in Proceedings of the National Academy of Sciences - PNAS (27-01-2009)“…Protein phosphorylation is central to the understanding of cellular signaling, and cellular signaling is suggested to play a major role in the regulation of…”
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Optimizing naloxone distribution to prevent opioid overdose fatalities: results from piloting the Systems Analysis and Improvement Approach within syringe service programs
Published in BMC health services research (22-03-2023)“…Opioid overdose fatalities are preventable with timely administration of naloxone, an opioid antagonist, during an opioid overdose event. Syringe service…”
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RNA–protein analysis using a conditional CRISPR nuclease
Published in Proceedings of the National Academy of Sciences - PNAS (02-04-2013)“…RNA-binding proteins control the fate and function of the transcriptome in all cells. Here we present technology for isolating RNA–protein partners efficiently…”
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Organize and mobilize for implementation effectiveness to improve overdose education and naloxone distribution from syringe services programs: a randomized controlled trial
Published in Implementation science : IS (28-02-2024)“…The United States (US) continues to face decades-long increases in opioid overdose fatalities. As an opioid overdose reversal medication, naloxone can…”
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Haemophilus influenzae serotype a invasive disease, Alaska, USA, 1983-2011
Published in Emerging infectious diseases (01-06-2013)“…Before introduction of Haemophilus influenzae type b (Hib) vaccines, rates of Hib disease in Alaska's indigenous people were among the highest in the world…”
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Systems analysis and improvement approach to improve naloxone distribution within syringe service programs: study protocol of a randomized controlled trial
Published in Implementation science : IS (03-08-2023)“…More than half a million Americans died of an opioid-related overdose between 1999 and 2020, the majority occurring between 2015 and 2020. The opioid overdose…”
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Best practices for community-based overdose education and naloxone distribution programs: results from using the Delphi approach
Published in Harm reduction journal (28-05-2022)“…Opioid-related overdose deaths have surged in the USA over the last two decades. Overdose fatalities are preventable with the timely administration of…”
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Availability of telehealth-based services at syringe services programs under the COVID-19 Public Health Emergency
Published in Harm reduction journal (02-09-2023)“…The expanded capacity of syringe services programs (SSPs) in the USA to integrate telehealth services was largely related to flexibility of buprenorphine…”
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15
Structure and function of respiratory turbinates in phocid seals
Published in Polar biology (01-02-2020)“…In terrestrial mammals, the respiratory turbinate bones within the nasal cavity are employed to conserve heat and water. In order to investigate whether…”
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Associations of marijuana with markers of chronic lung disease in people living with HIV
Published in HIV medicine (01-02-2021)“…Objectives The relationship between marijuana use and markers of chronic lung disease in people living with HIV (PLWH) is poorly understood. Methods We…”
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Crizotinib: A New Treatment Option for ALK-Positive Non-Small Cell Lung Cancer
Published in The Annals of pharmacotherapy (01-02-2013)“…OBJECTIVE: To review the characteristics and clinical trial data of crizotinib in ALK-positive non-small cell lung cancer (NSCLC). DATA SOURCE: A literature…”
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Bacterial Meningitis in the United States in 1995
Published in The New England journal of medicine (02-10-1997)“…Few medical advances in recent decades have affected pediatric infectious diseases as much as conjugate vaccines against Haemophilus influenzae type b disease…”
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Instant spectral assignment for advanced decision tree-driven mass spectrometry
Published in Proceedings of the National Academy of Sciences - PNAS (29-05-2012)“…We have developed and implemented a sequence identification algorithm (inSeq) that processes tandem mass spectra in real-time using the mass spectrometer's…”
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Financial barriers, facilitators, and strategies among syringe services programs in the U.S., and their impact on implementation and health outcomes
Published in SSM. Qualitative research in health (01-06-2024)“…Syringe Services Programs (SSPs) provide evidence-based services like drug use equipment to prevent infectious disease, overdose prevention education, and…”
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