Search Results - "Weng, Stephen"

Can machine-learning improve cardiovascular risk prediction using routine clinical data? by Weng, Stephen F, Reps, Jenna, Kai, Joe, Garibaldi, Jonathan M, Qureshi, Nadeem

“…Current approaches to predict cardiovascular risk fail to identify many people who would benefit from preventive treatment, while others receive unnecessary…”
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Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches by Weng, Stephen F, Vaz, Luis, Qureshi, Nadeem, Kai, Joe

“…Prognostic modelling using standard methods is well-established, particularly for predicting risk of single diseases. Machine-learning may offer potential to…”
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The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort by Nowakowska, Magdalena, Zghebi, Salwa S, Ashcroft, Darren M, Buchan, Iain, Chew-Graham, Carolyn, Holt, Tim, Mallen, Christian, Van Marwijk, Harm, Peek, Niels, Perera-Salazar, Rafael, Reeves, David, Rutter, Martin K, Weng, Stephen F, Qureshi, Nadeem, Mamas, Mamas A, Kontopantelis, Evangelos

“…The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the…”
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Sex, Age, and Socioeconomic Differences in Nonfatal Stroke Incidence and Subsequent Major Adverse Outcomes by Akyea, Ralph K., Vinogradova, Yana, Qureshi, Nadeem, Patel, Riyaz S., Kontopantelis, Evangelos, Ntaios, George, Asselbergs, Folkert W., Kai, Joe, Weng, Stephen F.

“…Data about variations in stroke incidence and subsequent major adverse outcomes are essential to inform secondary prevention and prioritizing resources to…”
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Improving identification of familial hypercholesterolaemia in primary care: Derivation and validation of the familial hypercholesterolaemia case ascertainment tool (FAMCAT) by Weng, Stephen F, Kai, Joe, Andrew Neil, H, Humphries, Steve E, Qureshi, Nadeem

“…Abstract Objective Heterozygous familial hypercholesterolaemia (FH) is a common autosomal dominant disorder. The vast majority of affected individuals remain…”
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Estimating overweight risk in childhood from predictors during infancy by Weng, Stephen F, Redsell, Sarah A, Nathan, Dilip, Swift, Judy A, Yang, Min, Glazebrook, Cris

“…The aim of this study was to develop and validate a risk score algorithm for childhood overweight based on a prediction model in infants. Analysis was…”
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Sex disparity in subsequent outcomes in survivors of coronary heart disease by Akyea, Ralph Kwame, Kontopantelis, Evangelos, Kai, Joe, Weng, Stephen F, Patel, Riyaz S, Asselbergs, Folkert W, Qureshi, Nadeem

“…Evidence on sex differences in outcomes after developing coronary heart disease (CHD) has focused on recurrent CHD, all-cause mortality or revascularisation…”
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Smoking and absence from work: systematic review and meta-analysis of occupational studies by Weng, Stephen F., Ali, Shehzad, Leonardi-Bee, Jo

“…Aims This study aimed to assess the association between smoking and absenteeism in working adults. Methods A systematic review and meta‐analysis was performed…”
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Long-term body mass index changes in overweight and obese adults and the risk of heart failure, cardiovascular disease and mortality: a cohort study of over 260,000 adults in the UK by Iyen, Barbara, Weng, Stephen, Vinogradova, Yana, Akyea, Ralph K, Qureshi, Nadeem, Kai, Joe

“…Although obesity is a well-recognised risk factor for cardiovascular disease (CVD), the impact of long-term body mass index (BMI) changes in overweight or…”
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Strategies for screening for familial hypercholesterolaemia in primary care and other community settings by Qureshi, Nadeem, Da Silva, Maria Luisa R, Abdul-Hamid, Hasidah, Weng, Stephen F, Kai, Joe, Leonardi-Bee, Jo

“…Familial hypercholesterolaemia is a common inherited condition that is associated with premature cardiovascular disease. The increased cardiovascular morbidity…”
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Obesity and long‐term outcomes after incident stroke: a prospective population‐based cohort study by Akyea, Ralph K., Doehner, Wolfram, Iyen, Barbara, Weng, Stephen F., Qureshi, Nadeem, Ntaios, George

“…Background The association between obesity, major adverse cardiovascular events (MACE), and mortality in patients with incident stroke is not well established…”
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Preconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease by Hussein, Norita, Weng, Stephen F, Kai, Joe, Kleijnen, Jos, Qureshi, Nadeem

“…Globally, about five per cent of children are born with congenital or genetic disorders. The most common autosomal recessive conditions are thalassaemia,…”
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Performance and clinical utility of supervised machine-learning approaches in detecting familial hypercholesterolaemia in primary care by Akyea, Ralph K., Qureshi, Nadeem, Kai, Joe, Weng, Stephen F.

“…Familial hypercholesterolaemia (FH) is a common inherited disorder, causing lifelong elevated low-density lipoprotein cholesterol (LDL-C). Most individuals…”
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Preconception risk assessment for thalassaemia, sickle cell disease, cystic fibrosis and Tay-Sachs disease by Hussein, Norita, Weng, Stephen F, Kai, Joe, Kleijnen, Jos, Qureshi, Nadeem

“…Globally, about five per cent of children are born with congenital or genetic disorders. The most common autosomal recessive conditions are thalassaemia,…”
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Case-finding and genetic testing for familial hypercholesterolaemia in primary care by Qureshi, Nadeem, Akyea, Ralph Kwame, Dutton, Brittany, Humphries, Steve E, Abdul Hamid, Hasidah, Condon, Laura, Weng, Stephen F, Kai, Joe

“…Familial hypercholesterolaemia (FH) is a common inherited disorder that remains mostly undetected in the general population. Through FH case-finding and direct…”
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Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study by Zghebi, Salwa S, Rutter, Martin K, Sun, Louise Y, Ullah, Waqas, Rashid, Muhammad, Ashcroft, Darren M, Steinke, Douglas T, Weng, Stephen, Kontopantelis, Evangelos, Mamas, Mamas A

“…Background The prevalence of multimorbidity in patients with acute myocardial infarction (AMI) is increasing. It is unclear whether comorbidities cluster into…”
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Detection of familial hypercholesterolaemia: external validation of the FAMCAT clinical case-finding algorithm to identify patients in primary care by Weng, Stephen, Kai, Joe, Akyea, Ralph, Qureshi, Nadeem

“…The vast majority of individuals with familial hypercholesterolaemia in the general population remain unidentified worldwide. Recognising patients most likely…”
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The value of aspartate aminotransferase and alanine aminotransferase in cardiovascular disease risk assessment by Weng, Stephen F, Kai, Joe, Guha, Indra Neil, Qureshi, Nadeem

“…ObjectiveAspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio, reflecting liver disease severity, has been associated with increased risk of…”
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Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models by Akyea, Ralph K, Leonardi-Bee, Jo, Asselbergs, Folkert W, Patel, Riyaz S, Durrington, Paul, Wierzbicki, Anthony S, Ibiwoye, Oluwaseun H, Kai, Joe, Qureshi, Nadeem, Weng, Stephen F

“…IntroductionCardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and…”
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Secondary prevention of cardiovascular disease: Time to rethink stratification of disease severity? by Akyea, Ralph K, Kai, Joe, Qureshi, Nadeem, Abdul Hamid, Hasidah, Weng, Stephen F

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