Search Results - "Weng, Liwei"

Functional combination-oriented module identification for adaptable-function mechanical product design by Weng, Liwei, Hu, Yongwen, Deng, Yi-Min

“…The adaptable-function mechanical product is not only of multiple functions, but also of more complex physical structure than products of fixed functions;…”
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Analysis of HETEs in human whole blood by chiral UHPLC-ECAPCI/HRMS by Mazaleuskaya, Liudmila L., Salamatipour, Ashkan, Sarantopoulou, Dimitra, Weng, Liwei, FitzGerald, Garret A., Blair, Ian A., Mesaros, Clementina

“…The biosynthesis of eicosanoids occurs enzymatically via lipoxygenases, cyclooxygenases, and cytochrome P450, or through nonenzymatic free radical reactions…”
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Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich’s Ataxia by Guo, Lili, Wang, Qingqing, Weng, Liwei, Hauser, Lauren A, Strawser, Cassandra J, Rocha, Agostinho G, Dancis, Andrew, Mesaros, Clementina, Lynch, David R, Blair, Ian A

“…Friedreich’s ataxia (FA) is an autosomal recessive disease caused by an intronic GAA triplet expansion in the FXN gene, leading to reduced expression of the…”
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Probing Interactions between Lysine Residues in Histone Tails and Nucleosomal DNA via Product and Kinetic Analysis by Weng, Liwei, Zhou, Chuanzheng, Greenberg, Marc M

“…The histone proteins in nucleosome core particles are known to catalyze DNA cleavage at abasic and oxidized abasic sites, which are produced by antitumor…”
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Simultaneous Quantification of Mitochondrial Mature Frataxin and Extra-Mitochondrial Frataxin Isoform E in Friedreich's Ataxia Blood by Wang, Qingqing, Laboureur, Laurent, Weng, Liwei, Eskenazi, Nicolas M, Hauser, Lauren A, Mesaros, Clementina, Lynch, David R, Blair, Ian A

“…Friedreich's ataxia (FRDA) is an autosomal recessive disease caused by an intronic guanine-adenine-adenine (GAA) triplet expansion in the frataxin ( ) gene,…”
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An oxidized abasic lesion inhibits base excision repair leading to DNA strand breaks in a trinucleotide repeat tract by Beaver, Jill M, Lai, Yanhao, Rolle, Shantell J, Weng, Liwei, Greenberg, Marc M, Liu, Yuan

“…Oxidative DNA damage and base excision repair (BER) play important roles in modulating trinucleotide repeat (TNR) instability that is associated with human…”
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Synthesis and Biological Studies of Inducible DNA Cross-Linking Agents by Weng, Xiaocheng, Ren, Lige, Weng, Liwei, Huang, Jing, Zhu, Shugao, Zhou, Xiang, Weng, Linhong

“…Checking the traps: When a phenyl selenide compound such as 1 was oxidized with sodium periodate or irradiated, an ortho‐quinone methide intermediate formed…”
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Synthesis and biological activities of quinazoline derivatives with ortho-phenol-quaternary ammonium salt groups by Zhang, Lixia, Ren, Lige, Bai, Minghui, Weng, Liwei, Huang, Jing, Wu, Lin, Deng, Minggang, Zhou, Xiang

“…One phenol-quaternary ammonium salt derivative with a flexible linker and three derivatives with a quinazoline moiety were present. Their binding affinities…”
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Quasi‐Indexer Ownership and Insider Trading: Evidence from Russell Index Reconstitutions by Hillegeist, Stephen A., Weng, Liwei

“…ABSTRACT Understanding the association between quasi‐indexer ownership and insider trading is important given the externalities that insider trading can impose…”
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Characterization and Quantification of Oxidized High Mobility Group Box 1 Proteoforms Secreted from Hepatocytes by Toxic Levels of Acetaminophen by Pirnie, Ross, Gillespie, Kevin P., Weng, Liwei, Mesaros, Clementina, Blair, Ian A.

“…The high mobility group box 1 (HMGB1), which is released during acute acetaminophen (APAP) overdose, is thought to mediate a subsequent immune response,…”
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Rapid Histone-Catalyzed DNA Lesion Excision and Accompanying Protein Modification in Nucleosomes and Nucleosome Core Particles by Weng, Liwei, Greenberg, Marc M

“…C5′-Hydrogen atoms are frequently abstracted during DNA oxidation. The oxidized abasic lesion 5′-(2-phosphoryl-1,4-dioxobutane) (DOB) is an electrophilic…”
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The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations by O’Connor, Roddy S., Guo, Lili, Ghassemi, Saba, Snyder, Nathaniel W., Worth, Andrew J., Weng, Liwei, Kam, Yoonseok, Philipson, Benjamin, Trefely, Sophie, Nunez-Cruz, Selene, Blair, Ian A., June, Carl H., Milone, Michael C.

“…Etomoxir (ETO) is a widely used small-molecule inhibitor of fatty acid oxidation (FAO) through its irreversible inhibitory effects on the carnitine…”
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Quantification of Serum High Mobility Group Box 1 by Liquid Chromatography/High-Resolution Mass Spectrometry: Implications for Its Role in Immunity, Inflammation, and Cancer by Weng, Liwei, Guo, Lili, Vachani, Anil, Mesaros, Clementina, Blair, Ian A

“…High mobility group box 1 (HMGB1) is a non-histone chromosomal protein, which can be secreted through a variety of pathways and bind to pattern recognition…”
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Extra-mitochondrial mouse frataxin and its implications for mouse models of Friedreich’s ataxia by Weng, Liwei, Laboureur, Laurent, Wang, Qingqing, Guo, Lili, Xu, Peining, Gottlieb, Leah, Lynch, David R., Mesaros, Clementina, Blair, Ian A.

“…Mature frataxin is essential for the assembly of iron–sulfur cluster proteins including a number of mitochondrial enzymes. Reduced levels of mature frataxin…”
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The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages by Vázquez‐Medina, José Pablo, Dodia, Chandra, Weng, Liwei, Mesaros, Clementina, Blair, Ian A., Feinstein, Sheldon I., Chatterjee, Shampa, Fisher, Aron B.

“…ABSTRACT Peroxiredoxin 6 (Prdx6) is essential for activation of NADPH oxidase type 2 (NOX2) in pulmonary microvascular endothelial cells (PMVECs), alveolar…”
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Characterization of a new N-terminally acetylated extra-mitochondrial isoform of frataxin in human erythrocytes by Guo, Lili, Wang, Qingqing, Weng, Liwei, Hauser, Lauren A., Strawser, Cassandra J., Mesaros, Clementina, Lynch, David R., Blair, Ian A.

“…Frataxin is a highly conserved protein encoded by the frataxin ( FXN ) gene. The full-length 210-amino acid form of protein frataxin (1–210; isoform A)…”
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Mutual Fund Liquidity Management, Stock Liquidity, and Corporate Disclosure by Weng, Liwei

“…This study presents the first evidence that mutual fund liquidity management affects both stock liquidity and information disclosure of portfolio firms. Using…”
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Evaluation of antibodies for western blot analysis of frataxin protein isoforms by Weng, Liwei, Wang, Qingqing, Yu, Sixiang, Yang, Xiaolu, Lynch, David R., Mesaros, Clementina, Blair, Ian A.

“…Frataxin is the protein that is down-regulated in Friedreich ataxia (FRDA), an autosomal recessive genetic disease caused by an intronic GAA repeat expansion…”
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Identification of proximal sites for unwound DNA substrate in E. coli topoisomerase I with oxidative crosslinking by Cheng, Bokun, Zhou, Qingxuan, Weng, Liwei, Leszyk, John D., Greenberg, Marc M., Tse-Dinh, Yuk-Ching

“…Topoisomerases catalyze changes in DNA topology by directing the movement of DNA strands through consecutive cleavage-rejoining reactions of the DNA backbone…”
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Deconvoluting the Reactivity of Two Intermediates Formed from Modified Pyrimidines by Weng, Liwei, Horvat, Sonia M, Schiesser, Carl H, Greenberg, Marc M

“…Generation of the 5-(2′-deoxyuridinyl)methyl radical (6) was reexamined. Trapping by 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl confirms that 6 is…”
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