Search Results - "Wendt, Thoralf"

Understanding RAGE, the receptor for advanced glycation end products by BIERHAUS, Angelika, HUMPERT, Per M, MORCOS, Michael, WENDT, Thoralf, CHAVAKIS, Triantafyllos, ARNOLD, Bernd, STERN, David M, NAWROTH, Peter P

“…Advanced glycation end products (AGEs), S100/calgranulins, HMGB1-proteins, amyloid-beta peptides, and the family of beta-sheet fibrils have been shown to…”
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A Mechanism Converting Psychosocial Stress into Mononuclear Cell Activation by Bierhaus, Angelika, Wolf, Jutta, Andrassy, Martin, Rohleder, Nicolas, Humpert, Per M., Petrov, Dimitri, Ferstl, Roman, von Eynatten, Maximilian, Wendt, Thoralf, Rudofsky, Gottfried, Joswig, Martina, Morcos, Michael, Schwaninger, Markus, McEwen, Bruce, Kirschbaum, Clemens, Nawroth, Peter P.

“…Little is known about the mechanisms converting psychosocial stress into cellular dysfunction. Various genes, up-regulated in atherosclerosis but also by…”
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Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products by Chang, Jong Sun, Wendt, Thoralf, Qu, Wu, Kong, Linghua, Zou, Yu Shan, Schmidt, Ann Marie, Yan, Shi-Fang

“…Myocardial infarction, stroke, and venous thromboembolism are characterized by oxygen deprivation. In hypoxia, biological responses are activated that evoke…”
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RAGE blockade stabilizes established atherosclerosis in diabetic apolipoprotein E-null mice by BUCCIARELLI, Loredana G, WENDT, Thoralf, KASHYAP, Yogita, STERN, David M, SCHMIDT, Ann Marie, WU QU, YAN LU, LALLA, Evanthia, LING LING RONG, GOOVA, Mouza T, MOSER, Bernhard, KISLINGER, Thomas, LEE, Daniel C

“…Previous studies suggested that blockade of RAGE in diabetic apolipoprotein (apo) E-null mice suppressed early acceleration of atherosclerosis. A critical test…”
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RAGE Drives the Development of Glomerulosclerosis and Implicates Podocyte Activation in the Pathogenesis of Diabetic Nephropathy by Wendt, Thoralf M., Tanji, Nozomu, Guo, Jiancheng, Kislinger, Thomas R., Qu, Wu, Lu, Yan, Bucciarelli, Loredana G., Rong, Ling Ling, Moser, Bernhard, Markowitz, Glen S., Stein, Gunther, Bierhaus, Angelika, Liliensiek, Birgit, Arnold, Bernd, Nawroth, Peter P., Stern, David M., D'Agati, Vivette D., Schmidt, Ann Marie

“…Diabetic nephropathy ensues from events involving earliest changes in the glomeruli and podocytes, followed by accumulation of extracellular matrix in the…”
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The RAGE Axis in Early Diabetic Retinopathy by Barile, Gaetano R, Pachydaki, Sophia I, Tari, Samir R, Lee, Song E, Donmoyer, Christine M, Ma, Wanchao, Rong, Ling Ling, Buciarelli, Loredana G, Wendt, Thoralf, Horig, Heidi, Hudson, Barry I, Qu, Wu, Weinberg, Alan D, Yan, Shi Fang, Schmidt, Ann Marie

“…The receptor for advanced glycation end products (AGEs) has been implicated in the pathogenesis of diabetic complications. This study was conducted to…”
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Acute Hyperglycemia Causes Intracellular Formation of CML and Activation of ras, p42/44 MAPK, and Nuclear Factor κB in PBMCs by SCHIEKOFER, Stephan, ANDRASSY, Martin, SCHLEICHER, Erwin, HÄRING, Hans-Ulrich, NAWROTH, Peter P, BIERHAUS, Angelika, JIANG CHEN, RUDOFSKY, Gottfried, SCHNEIDER, Jochen, WENDT, Thoralf, STEFAN, Norbert, HUMPERT, Per, FRITSCHE, Andreas, STUMVOLL, Michael

“…Acute Hyperglycemia Causes Intracellular Formation of CML and Activation of ras, p42/44 MAPK, and Nuclear Factor κB in PBMCs Stephan Schiekofer 1 , Martin…”
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Posttranslationally Modified Proteins as Mediators of Sustained Intestinal Inflammation by Andrassy, Martin, Igwe, John, Autschbach, Frank, Volz, Christian, Remppis, Andrew, Neurath, Markus F., Schleicher, Erwin, Humpert, Per M., Wendt, Thoralf, Liliensiek, Birgit, Morcos, Michael, Schiekofer, Stephan, Thiele, Kirsten, Chen, Jiang, Kientsch-Engel, Rose, Schmidt, Ann-Marie, Stremmel, Wolfgang, Stern, David M., Katus, Hugo A., Nawroth, Peter P., Bierhaus, Angelika

“…Oxidative and carbonyl stress leads to generation of N ε-carboxymethyllysine-modified proteins (CML-mps), which are known to bind the receptor for advanced…”
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Receptor for Advanced Glycation End Products Mediates Inflammation and Enhanced Expression of Tissue Factor in Vasculature of Diabetic Apolipoprotein E–Null Mice by Kislinger, Thomas, Tanji, Nozomu, Wendt, Thoralf, Qu, Wu, Lu, Yan, Ferran, Luis J, Taguchi, Akihiko, Olson, Kim, Bucciarelli, Loredana, Goova, Mouza, Hofmann, Marion A, Cataldegirmen, Guellue, D’Agati, Vivette, Pischetsrieder, Monika, Stern, David M, Schmidt, Ann Marie

“…ABSTRACT—Advanced glycation end products (AGEs) and their cell surface receptor, RAGE, have been implicated in the pathogenesis of diabetic complications…”
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Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders by Hudson, Barry I, Bucciarelli, Loredana G, Wendt, Thoralf, Sakaguchi, Taichi, Lalla, Evanthia, Qu, Wu, Lu, Yan, Lee, Larisse, Stern, David M, Naka, Yoshifumi, Ramasamy, Ravichandran, Yan, Shi Du, Yan, Shi Fang, D’Agati, Vivette, Schmidt, Ann Marie

“…The glycation and oxidation of proteins/lipids leads to the generation of a new class of biologically active moieties, the advanced glycation endproducts…”
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Diabetic vascular disease: it's all the RAGE by Hudson, Barry I, Wendt, Thoralf, Bucciarelli, Loredana G, Rong, Ling Ling, Naka, Yoshifumi, Yan, Shi Fang, Schmidt, Ann Marie

“…The major consequence of long-term diabetes is the increased incidence of disease of the vasculature. Of the underlying mechanisms leading to disease, the…”
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RAGE and its ligands: a lasting memory in diabetic complications? by Yan, Shi-Fang, Ramasamy, Ravichandran, Bucciarelli, Loredana G, Wendt, Thoralf, Lee, Larisse K, Hudson, Barry I, Stern, David M, Lalla, Evanthia, DU Yan, Shi, Rong, Ling Ling, Naka, Yoshifumi, Schmidt, Ann Marie

“…The complications of diabetes are myriad and represent a rising cause of morbidity and mortality, particularly in the Western world. The update of the Diabetes…”
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New treatments for diabetic neuropathy: pathogenetically oriented treatment by Bierhaus, Angelika, Humpert, Per M, Rudofsky, Gottfried, Wendt, Thoralf, Morcos, Michael, Hamann, Andreas, Nawroth, Peter P

“…Although there is clear evidence from experimental diabetic neuropathy (DN) models that the multiple pathways involved in neuronal degeneration cause…”
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Induction of p27KIP1 after unilateral ureteral obstruction is independent of angiotensin II by Gerth, Jens H., Kriegsmann, Jörg, Trinh, T. Tong, Stahl, Rolf A.K., Wendt, Thoralf, Sommer, Manfred, Stein, Günter, Wolf, Gunter

“…Induction of p27KIP1 after unilateral ureteral obstruction is independent of angiotensin II. Unilateral ureteral obstruction (UUO) is characterized by…”
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RAGE modulates vascular inflammation and atherosclerosis in a murine model of type 2 diabetes by Wendt, Thoralf, Harja, Evis, Bucciarelli, Loredana, Qu, Wu, Lu, Yan, Rong, Ling Ling, Jenkins, Daniel G., Stein, Guenther, Schmidt, Ann Marie, Yan, Shi Fang

“…Previous studies demonstrated that induction of diabetes with streptozotocin (stz) accelerated atherosclerosis in hyperlipidemic apo E null (−/−) mice…”
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Glucose, glycation, and RAGE: Implications for amplification of cellular dysfunction in diabetic nephropathy by WENDT, Thoralf, TANJI, Nozomu, SCHMIDT, Ann Marie, GUO, Jiancheng, HUDSON, Barry I, BIERHAUS, Angelika, RAMASAMY, Ravichandran, ARNOLD, Bernd, NAWROTH, Peter P, SHI FANG YAN, D'AGATI, Vivette

“…Receptor for advanced glycation endproducts (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. Driven by rapid…”
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RAGE Axis: Animal Models and Novel Insights Into the Vascular Complications of Diabetes by Naka, Yoshifumi, Bucciarelli, Loredana G, Wendt, Thoralf, Lee, Larisse K, Rong, Ling Ling, Ramasamy, Ravichandran, Yan, Shi Fang, Schmidt, Ann Marie

“…Receptor for AGE (RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. Engagement of RAGE by its signal transduction…”
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RAGE modulates peripheral nerve regeneration via recruitment of both inflammatory and axonal outgrowth pathways by Rong, Ling Ling, Yan, Shi‐Fang, Wendt, Thoralf, Hans, Diana, Pachydaki, Sophia, Bucciarelli, Loredana G., Adebayo, Adebukola, Qu, Wu, Lu, Yan, Kostov, Konstantin, Lalla, Evanthia, Yan, Shi Du, Gooch, Clifton, Szabolcs, Matthias, Trojaborg, Werner, Hays, Arthur P., Schmidt, Ann Marie

“…Axotomy of peripheral nerve stimulates events in multiple cell types that initiate a limited inflammatory response to axonal degeneration and simultaneous…”
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Receptor for advanced glycation endproducts (RAGE) and vascular inflammation: insights into the pathogenesis of macrovascular complications in diabetes by Wendt, Thoralf, Bucciarelli, Loredana, Qu, Wu, Lu, Yan, Yan, Shi Fang, Stern, David M, Schmidt, Ann Marie

“…The incidence and severity of atherosclerosis is increased in patients with diabetes. Indeed, accelerated macrovascular disease in diabetic patients has…”
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Plasma sRAGE Is Independently Associated With Urinary Albumin Excretion in Type 2 Diabetes by Humpert, Per M, Kopf, Stefan, Djuric, Zdenka, Wendt, Thoralf, Morcos, Michael, Nawroth, Peter P, Bierhaus, Angelika

“…The receptor for advanced glycation end products (RAGE) has been shown to be involved in the pathogenesis of late diabetes complications. However, little is…”
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