Search Results - "Wendt, Igor R"

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    Fructose diet treatment in mice induces fundamental disturbance of cardiomyocyte Ca2+ handling and myofilament responsiveness by Mellor, Kimberley M, Wendt, Igor R, Ritchie, Rebecca H, Delbridge, Lea M D

    “…High fructose intake has been linked to insulin resistance and cardiac pathology. Dietary fructose-induced myocardial signaling and morphological alterations…”
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    Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro by Mellor, Kimberley M, Bell, James R, Wendt, Igor R, Davidoff, Amy J, Ritchie, Rebecca H, Delbridge, Lea M D

    Published in PloS one (29-09-2011)
    “…High dietary fructose has structural and metabolic cardiac impact, but the potential for fructose to exert direct myocardial action is uncertain. Cardiomyocyte…”
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    Journal Article
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    Exploiting cGMP-based therapies for the prevention of left ventricular hypertrophy: NO and beyond by Ritchie, Rebecca H, Irvine, Jennifer C, Rosenkranz, Anke C, Patel, Ruchi, Wendt, Igor R, Horowitz, John D, Kemp-Harper, Barbara K

    Published in Pharmacology & therapeutics (Oxford) (01-12-2009)
    “…Left ventricular hypertrophy (LVH), an increased left ventricular (LV) mass, is common to many cardiovascular disorders, initially developing as an adaptive…”
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    Energy cost of contraction in rat urinary bladder smooth muscle during anoxia by Wendt, Igor R, Paul, Richard J

    “…Summary 1. The aim of the present study was to investigate the effects of hypoxia on energy metabolism and contraction of rat urinary bladder smooth muscle,…”
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    Ageing-related cardiomyocyte functional decline is sex and angiotensin II dependent by Mellor, Kimberley M., Curl, Claire L., Chandramouli, Chanchal, Pedrazzini, Thierry, Wendt, Igor R., Delbridge, Lea M. D.

    Published in AGE (01-06-2014)
    “…Clinically, heart failure is an age-dependent pathological phenomenon and displays sex-specific characteristics. The renin-angiotensin system mediates cardiac…”
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    Sex differences in cardiac muscle responsiveness to Ca2+ and L-type Ca2+ channel modulation by CURL, Claire L, DELBRIDGE, Lea M. D, WENDT, Igor R

    Published in European journal of pharmacology (31-05-2008)
    “…This study investigated sex-related differences in rat papillary muscle force generation in response to altered extracellular [Ca2+] ([Ca2+](o), 0.2 to 5.0 mM)…”
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    Effects of ovariectomy and 17β-oestradiol replacement on [Ca2+]i in female rat cardiac myocytes by Curl, Claire L, Wendt, Igor R, Canny, Benedict J, Kotsanas, George

    “…Summary 1. The present study investigated the effects of ovariectomy (OVX) and 17β‐oestradiol replacement on [Ca2+]i in rat freshly isolated cardiac myocytes…”
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    Fructose Modulates Cardiomyocyte Excitation-Contraction Coupling and Ca.sup.2+ Handling In Vitro by Mellor, Kimberley M, Bell, James R, Wendt, Igor R, Davidoff, Amy J, Ritchie, Rebecca H, Delbridge, Lea M. D

    Published in PloS one (29-09-2011)
    “…Background High dietary fructose has structural and metabolic cardiac impact, but the potential for fructose to exert direct myocardial action is uncertain…”
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    Journal Article
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    Sex differences in cardiac muscle responsiveness to Ca 2+ and L-type Ca 2+ channel modulation by Curl, Claire L., Delbridge, Lea M.D., Wendt, Igor R.

    Published in European journal of pharmacology (2008)
    “…This study investigated sex-related differences in rat papillary muscle force generation in response to altered extracellular [Ca 2+] ([Ca 2+] o, 0.2 to…”
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    Journal Article
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    EFFECTS OF PYRUVATE ON INTRACELLULAR Ca 2+ REGULATION IN CARDIAC MYOCYTES FROM NORMAL AND DIABETIC RATS by Mellors, Linda J, Kotsanas, George, Wendt, Igor R

    “…1. Pyruvate has been shown to enhance the contractile performance of cardiac muscle when provided as an alternative substrate to glucose. The aims of the…”
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    EFFECTS OF PYRUVATE ON INTRACELLULAR Ca2+ REGULATION IN CARDIAC MYOCYTES FROM NORMAL AND DIABETIC RATS by Mellors, Linda J, Kotsanas, George, Wendt, Igor R

    “…SUMMARY 1. Pyruvate has been shown to enhance the contractile performance of cardiac muscle when provided as an alternative substrate to glucose. The aims of…”
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    Force, membrane potential and cytoplasmic Ca 2+ responses to cyclic nucleotides in rat anococcygeus muscle by Raymond, Gregory L., Tonta, Mary A., Parkington, Helena C., Wendt, Igor R.

    Published in European journal of pharmacology (1998)
    “…Simultaneous recordings of membrane potential and force, and cytoplasmic calcium ([Ca 2+] i) and force were made in rat anococcygeus to determine whether…”
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    Contractile and metabolic properties of longitudinal smooth muscle from rat urinary bladder and the effects of aging by Munro, D D, Wendt, I R

    Published in The Journal of urology (01-08-1993)
    “…Longitudinal smooth muscle strips taken from the urinary bladders of Sprague-Dawley rats, aged approximately 6 months and 24 months, were examined under a…”
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    Force, membrane potential and cytoplasmic Ca2+ responses to cyclic nucleotides in rat anococcygeus muscle by RAYMOND, G. L, TONTA, M. A, PARKINGTON, H. C, WENDT, I. R

    Published in European journal of pharmacology (04-12-1998)
    “…Simultaneous recordings of membrane potential and force, and cytoplasmic calcium ([Ca2+]i) and force were made in rat anococcygeus to determine whether…”
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    Intracellular Ca2+, force and activation heat in rabbit papillary muscle: effects of 2,3-butanedione monoxime by Kotsanas, G, Holroyd, S M, Wendt, I R, Gibbs, C L

    “…We have investigated the effects of 2,3-butanedione monoxime (BDM) and mannitol on Ca2+ metabolism in rabbit cardiac muscle. Simultaneous measurements of force…”
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