Search Results - "Wendt, Edgar Heinz Uwe"

A novel multi-parametric analysis of non-invasive methods to assess animal distress during chronic pancreatitis by Abdelrahman, Ahmed, Kumstel, Simone, Zhang, Xianbin, Liebig, Marie, Wendt, Edgar Heinz Uwe, Eichberg, Johanna, Palme, Rupert, Thum, Thomas, Vollmar, Brigitte, Zechner, Dietmar

“…Ethical responsibility, legal requirements and the need to improve the quality of research create a growing interest in the welfare of laboratory animals…”
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Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism by Kumstel, Simone, Schreiber, Tim, Goldstein, Lea, Stenzel, Jan, Lindner, Tobias, Joksch, Markus, Zhang, Xianbin, Wendt, Edgar Heinz Uwe, Schönrogge, Maria, Krause, Bernd, Vollmar, Brigitte, Zechner, Dietmar

“…Pancreatic cancer is the fourth leading cause of cancer death, with a 5-year survival rate of 10%. A stagnant high mortality rate over the last decades…”
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Benefits of non-invasive methods compared to telemetry for distress analysis in a murine model of pancreatic cancer by Kumstel, Simone, Vasudevan, Praveen, Palme, Rupert, Zhang, Xianbin, Wendt, Edgar Heinz Uwe, David, Robert, Vollmar, Brigitte, Zechner, Dietmar

“…[Display omitted] •The suitability of methods for analysing distress in laboratory mice was assessed.•Non-invasive vs. telemetric methods were compared in an…”
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Blocking Autophagy in Cancer-Associated Fibroblasts Supports Chemotherapy of Pancreatic Cancer Cells by Zhang, Xianbin, Schönrogge, Maria, Eichberg, Johanna, Wendt, Edgar Heinz Uwe, Kumstel, Simone, Stenzel, Jan, Lindner, Tobias, Jaster, Robert, Krause, Bernd Joachim, Vollmar, Brigitte, Zechner, Dietmar

“…In this study we evaluated the interaction of pancreatic cancer cells, cancer-associated fibroblasts, and distinct drugs such as α-cyano-4-hydroxycinnamate,…”
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Galloflavin Plus Metformin Treatment Impairs Pancreatic Cancer Cells by Wendt, Edgar Heinz Uwe, Schoenrogge, Maria, Vollmar, Brigitte, Zechner, Dietmar

“…In this study, we evaluated the effect of galloflavin, an inhibitor of lactate dehydrogenase, in combination with metformin, an anti-diabetic drug and…”
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MicroRNAs as systemic biomarkers to assess distress in animal models for gastrointestinal diseases by Kumstel, Simone, Janssen-Peters, Heike, Abdelrahman, Ahmed, Tang, Guanglin, Xiao, Ke, Ernst, Nicole, Wendt, Edgar Heinz Uwe, Palme, Rupert, Seume, Nico, Vollmar, Brigitte, Thum, Thomas, Zechner, Dietmar

“…Severity assessment of animal experiments is mainly conducted by using subjective parameters. A widely applicable biomarker to assess animal distress could…”
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