Search Results - "Wen, Yu‐Mei"

The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer by Jin, Lingtao, Chun, Jaemoo, Pan, Chaoyun, Kumar, Avi, Zhang, Guojing, Ha, Youna, Li, Dan, Alesi, Gina N., Kang, Yibin, Zhou, Lu, Yu, Wen-Mei, Magliocca, Kelly R., Khuri, Fadlo R., Qu, Cheng-Kui, Metallo, Christian, Owonikoko, Taofeek K., Kang, Sumin

“…Loss of LKB1 is associated with increased metastasis and poor prognosis in lung cancer, but the development of targeted agents is in its infancy. Here we…”
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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment by Dong, Lei, Yu, Wen-Mei, Zheng, Hong, Loh, Mignon L., Bunting, Silvia T., Pauly, Melinda, Huang, Gang, Zhou, Muxiang, Broxmeyer, Hal E., Scadden, David T., Qu, Cheng-Kui

“…Mutations in the protein tyrosine phosphatase SHP2 affect cells in the bone marrow environment, which leads to aberrant activation of resident haematopoietic…”
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The role of bacterial biofilm in persistent infections and control strategies by Chen, Li, Wen, Yu‐mei

“…Bacterial biofilms can be viewed as a specific type of persistent bacterial infection. After initial invasion, microbes can attach to living and non-living…”
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Immunoregulatory functions of immune complexes in vaccine and therapy by Wen, Yu‐mei, Mu, Libing, Shi, Yan

“…Clinical and experimental preparations of IgG/soluble antigen complexes, as well as those formed following antibody therapy in vivo, are multifaceted immune…”
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Future science prize goes to EMI editorial board members and the science of emerging infections by Lu, Shan, Wen, Yu-mei

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Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation by Yu, Wen-Mei, Liu, Xia, Shen, Jinhua, Jovanovic, Olga, Pohl, Elena E., Gerson, Stanton L., Finkel, Toren, Broxmeyer, Hal E., Qu, Cheng-Kui

“…The regulation and coordination of mitochondrial metabolism with hematopoietic stem cell (HSC) self-renewal and differentiation is not fully understood. Here…”
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From therapeutic antibodies to immune complex vaccines by Wang, Xuan-Yi, Wang, Bin, Wen, Yu-Mei

“…In recent years, therapeutic monoclonal antibodies have made impressive progress, providing great benefit by successfully treating malignant and chronic…”
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A study on gender differences in newly detected leprosy cases in Sichuan, China, 2000–2015 by Liu, Yang‐Ying, Yu, Mei‐Wen, Ning, Yong, Wang, Hao

“…Background Many researches on gender differences in leprosy found that female patients were detected with the disease later and had more serious disabilities…”
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Chimeric antigen receptors of HBV envelope proteins inhibit hepatitis B surface antigen secretion by Wang, Yang, Li, Qiqi, Li, Cheng, Wang, Cong, Wang, Shijie, Yuan, Wenjie, Yu, Demin, Zhang, Ke, Shi, Bisheng, Chen, Xiaomei, Liu, Tiantian, Yuan, Zhenghong, Tong, Shuping, Nassal, Michael, Wen, Yu-Mei, Wang, Yong-Xiang

“…Chronic hepatitis B (CHB) caused by HBV infection greatly increases the risk of liver cirrhosis and hepatocellular carcinoma. Hepatitis B surface antigen…”
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A 33-residue peptide tag increases solubility and stability of Escherichia coli produced single-chain antibody fragments by Wang, Yang, Yuan, Wenjie, Guo, Siqi, Li, Qiqi, Chen, Xiaomei, Li, Cheng, Liu, Qianying, Sun, Lei, Chen, Zhenguo, Yuan, Zhenghong, Luo, Cheng, Chen, Shijie, Tong, Shuping, Nassal, Michael, Wen, Yu-Mei, Wang, Yong-Xiang

“…Single-chain variable fragments (scFvs), composed of variable domains of heavy and light chains of an antibody joined by a linker, share antigen binding…”
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Suspicious symptom monitoring for leprosy: an optimal practice for early detection under a low endemic situation in Zhejiang Province, China by Shen, Yun‐Liang, Kong, Wen‐Ming, Yu, Mei‐Wen, Wu, Li‐Mei, Fei, Li‐Juan

“…Background Leprosy is a chronic infectious disease that causes disabilities and deformities. Early detection is a major strategy for leprosy control. This…”
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Leprosy among new child cases in China: Epidemiological and clinical analysis from 2011 to 2020 by Peng, Jiayi, Sun, Peiwen, Wang, Le, Wang, Hongsheng, Long, Siyu, Yu, Mei-Wen

“…Leprosy, caused by Mycobacterium leprae infection, mainly affects skin and peripheral nerves and may further lead to disability and deformity if not treated…”
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The y271 and i274 amino acids in reverse transcriptase of human immunodeficiency virus-1 are critical to protein stability by Zhang, Hao-Jie, Wang, Yong-Xiang, Wu, Hao, Jin, Dong-Yan, Wen, Yu-Mei, Zheng, Bo-Jian

“…Reverse transcriptase (RT) of human immunodeficiency virus (HIV)-1 plays a key role in initiating viral replication and is an important target for developing…”
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A passive current sensor employing self-biased magnetoelectric transducer and high-permeability nanocrystalline flux concentrator by Zhang, Ji-Tao, Wen, Yu-Mei, Li, Ping

“…A passive current sensor, consisting of SmFe 2 /PZT/SmFe 2 self-biased magnetoelectric (ME) composite and Fe 73.5 Cu 1 Nb 3 Si 13.5 B 9 nanocrystalline flux…”
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AMPK activator-treated human cardiac spheres enhance maturation and enable pathological modeling by Li, Dong, Armand, Lawrence C, Sun, Fangxu, Hwang, Hyun, Wolfson, David, Rampoldi, Antonio, Liu, Rui, Forghani, Parvin, Hu, Xin, Yu, Wen-Mei, Qu, Cheng-Kui, Jones, Dean P, Wu, Ronghu, Cho, Hee Cheol, Maxwell, Joshua T, Xu, Chunhui

“…Cardiac pathological outcome of metabolic remodeling is difficult to model using cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CMs)…”
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Non-lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells by Xu, Dan, Liu, Xia, Yu, Wen-Mei, Meyerson, Howard J, Guo, Caiying, Gerson, Stanton L, Qu, Cheng-Kui

“…Activating mutations in protein tyrosine phosphatase 11 (Ptpn11) have been identified in childhood acute leukemias, in addition to juvenile myelomonocytic…”
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Maintenance of mouse hematopoietic stem cells ex vivo by reprogramming cellular metabolism by Liu, Xia, Zheng, Hong, Yu, Wen-Mei, Cooper, Todd M., Bunting, Kevin D., Qu, Cheng-Kui

“…The difficulty in maintaining the reconstituting capabilities of hematopoietic stem cells (HSCs) in culture outside of the bone marrow microenvironment has…”
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Activating mutations in protein tyrosine phosphatase Ptpn11 (Shp2) enhance reactive oxygen species production that contributes to myeloproliferative disorder by Xu, Dan, Zheng, Hong, Yu, Wen-Mei, Qu, Cheng-Kui

“…Gain of function (GOF) mutations in protein tyrosine phosphatase Ptpn11 have been identified in childhood leukemias, and these mutations are sufficient to…”
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Use of oral anticoagulants and its associated factors among nonvalvular atrial fibrillation patients with new‐onset acute ischemic stroke: A report from the China Atrial Fibrillation Registry study by Wang, Jing‐Rong, Du, Xin, Dong, Jian‐Zeng, Chang, San‐Shuai, Jiang, Chao, Sang, Cai‐Hua, Long, De‐Yong, Tang, Ri‐Bo, Zhang, Hai‐Bin, Guo, Jin‐Cheng, Wen, Yu‐Mei, He, Liu, Ma, Chang‐Sheng

“…Background The adherence of oral anticoagulant (OAC) therapy among nonvalvular atrial fibrillation (NVAF) patients with acute ischemic stroke (AIS) in China…”
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Expression Level of Small Envelope Protein in Addition to Sequence Divergence inside Its Major Hydrophilic Region Contributes to More Efficient Surface Antigen Secretion by Hepatitis B Virus Subgenotype D2 than Subgenotype A2 by Wang, Qianru, Fu, Shuwen, Zhang, Jing, Yuan, Quan, Li, Jisu, Xia, Ningshao, Wen, Yu-Mei, Wang, Yongxiang, Tong, Shuping

“…Hepatitis B surface antigen (HBsAg) promotes persistent hepatitis B virus (HBV) infection. It primarily corresponds to small (S) envelope protein secreted as…”
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