Search Results - "Wen, Ya Feng"

Best Practices for Pharmacokinetic Studies of New Chemical Entities by Wen, Ya‐Feng, Graaf, Piet H.

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Evaluation of Truncated AUC as an Alternative Measure to Assess Pharmacokinetic Comparability in Bridging Biologic-Device Using Prefilled Syringes and Autoinjectors by Wen, Ya-Feng, Ji, Ping, Schrieber, Sarah J, Rathi, Sneha, McGuirt, Delaney, Liu, Jiang, Chen, Jianmeng, Wang, Yow-Ming, Doddapaneni, Suresh, Sahajwalla, Chandrahas

“…Pharmacokinetic (PK) comparisons between therapeutic biologics have largely been based on total area under the concentration-time curve (AUC) and maximum…”
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Population pharmacokinetics, pharmacodynamics and pharmacogenetics modelling of oxypurinol in Hmong adults with gout and/or hyperuricemia by Wen, Ya-Feng, Brundage, Richard C, Roman, Youssef M, Culhane-Pera, Kathleen A, Straka, Robert J

“…The aim of this study was to quantify identifiable sources of variability, including key pharmacogenetic variants in oxypurinol pharmacokinetics and their…”
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Hmong microbiome ANd Gout, Obesity, Vitamin C (HMANGO-C): A phase II clinical study protocol by Wen, Ya-Feng, Culhane-Pera, Kathleen A, Pergament, Shannon L, Moua, Yeng, Vue, Bai, Yang, Toua, Lo, Muaj, Sun, Boguang, Knights, Dan, Straka, Robert J

“…Hmong men in Minnesota exhibit a high prevalence of gout and hyperuricemia. Although evidence of vitamin C's effectiveness as a treatment for gout is mixed,…”
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Differences in Predicted Warfarin Dosing Requirements Between Hmong and East Asians Using Genotype‐Based Dosing Algorithms by Sun, Boguang, Wen, Ya‐Feng, Culhane‐Pera, Kathleen A., Lo, Muaj, Xiong, Txia, Lee, Koobmeej, Peng, Kerui, Thyagarajan, Bharat, Bishop, Jeffrey R., Zierhut, Heather, Straka, Robert J.

“…Introduction Warfarin’s narrow therapeutic index and high variability in dosage requirements make dosage selection critical. Genetic factors are known to…”
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The advantages of next-generation sequencing technology in the detection of different sources of abscess by Guo, Ling-Yun, Feng, Wen-Ya, Guo, Xin, Liu, Bing, Liu, Gang, Dong, Jie

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Effect of ginger supplementation on the fecal microbiome in subjects with prior colorectal adenoma by Prakash, Ajay, Rubin, Nathan, Staley, Christopher, Onyeaghala, Guillaume, Wen, Ya-Feng, Shaukat, Aasma, Milne, Ginger, Straka, Robert J., Church, Timothy R., Prizment, Anna

“…Ginger has been associated with a decreased incidence of colorectal cancer (CRC) through reduction in inflammatory pathways and inhibition of tumor growth…”
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Potential Clinical Relevance of Differences in Allele Frequencies Found within Very Important Pharmacogenes between Hmong and East Asian Populations by Wen, Ya‐Feng, Culhane‐Pera, Kathleen A., Thyagarajan, Bharat, Bishop, Jeffrey R., Zierhut, Heather, Lo, Muaj, Xiong, Txia, Peng, Kerui, Holzer, Katherine, Lee, Koobmeej, Straka, Robert J.

“…Objectives Implementing pharmacogenetics for very important pharmacogenes (VIPs) holds the promise of improving clinical outcomes through optimal medication…”
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The diagnostic value of metagenomic next-generation sequencing for identifying Streptococcus pneumoniae in paediatric bacterial meningitis by Zhang, Xi-Xi, Guo, Ling-Yun, Liu, Lin-Lin, Shen, Ao, Feng, Wen-Ya, Huang, Wen-Hua, Hu, Hui-Li, Hu, Bing, Guo, Xin, Chen, Tian-Ming, Chen, He-Ying, Jiang, Yong-Qiang, Liu, Gang

“…There is currently no research on the diagnostic value of metagenomic next-generation sequencing (mNGS) for a single pathogens in CSF. The aim of this study…”
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Interaction between HLA-B60 and HLA-B27 as a Better Predictor of Ankylosing Spondylitis in a Taiwanese Population by Wei, James Cheng-Chung, Sung-Ching, Henry Wong, Hsu, Yu-Wen, Wen, Ya-Feng, Wang, Wen-Chang, Wong, Ruey-Hong, Lu, Hsing-Fang, Gaalen, Floris A van, Chang, Wei-Chiao

“…Ankylosing spondylitis (AS) is a form of chronic inflammatory spondyloarthritis (SpA) that causes pain and stiffness in spines or joints. Human leukocyte…”
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Evaluation of next-generation sequencing for the pathogenic diagnosis of children brain abscesses by Hu, Hui-li, Guo, Ling-yun, Wu, Hong-long, Feng, Wen-ya, Chen, Tian-ming, Liu, Gang

“…In this study, we applied metagenomic next-generation sequencing (mNGS) to detect the causative pathogens in brain abscess samples from 4 pediatric patients…”
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Clinical characteristics and etiology of bacterial meningitis in Chinese children >28 days of age, January 2014–December 2016: A multicenter retrospective study by Li, Chi, Feng, Wen-ya, Lin, Ai-wei, Zheng, Guo, Wang, Yan-chun, Han, Yan-jun, Zhong, Jian-min, Bi, Jing, Luo, Qiong, Zhao, Fang-chao, Jin, Ping, Guo, Ling-yun, Li, Na, Yu, Jie, Yang, Xiao-tao, Liang, Jun, Deng, Ji-kui, Li, Yong-jun, Wang, Yu-jiao, Yu, Xiong-ying, Wang, Dong-meng, Ru, Liang, Chen, Juan, Yang, Yong-hong, Yang, Qiao-zhi, Liu, Gang

“…To explore the clinical characteristics and etiology of bacterial meningitis (BM) in Chinese children. BM cases in children 28days to 18 years old were…”
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Close correlation between season of birth and the prevalence of bronchial asthma in a Taiwanese population by Chang, Wei-Chiao, Yang, Kuender D, Wu, Man-Tzu Marcie, Wen, Ya-Feng, Hsi, Edward, Chang, Jen-Chieh, Lin, You-Meei, Kuo, Ho-Chang, Chang, Wei-Pin

“…Bronchial asthma (BA), atopic dermatitis (AD), and allergic rhinitis (AR) are common allergic diseases. Environmental factors were indicated to influence the…”
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rs10865331 associated with susceptibility and disease severity of ankylosing spondylitis in a Taiwanese population by Wen, Ya-Feng, Wei, James Cheng-Chung, Hsu, Yu-Wen, Chiou, Hung-Yi, Wong, Henry Sung-Ching, Wong, Ruey-Hong, Ikegawa, Shiro, Chang, Wei-Chiao

“…Ankylosing spondylitis (AS) is a highly familial rheumatic disorder and is considered as a chronic inflammatory disease. Genetic factors are involved in the…”
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Development of chloroplast microsatellite markers for Glyptostrobus pensilis (Cupressaceae) by Yan, Ya‐Dan, Li, Xin‐Yu, Worth, James R. P., Lin, Xue‐Ying, Ruhsam, Markus, Chen, Lu, Wu, Xing‐Tong, Wang, Min‐qiu, Thomas, Philip I., Wen, Ya‐Feng

“…Premise Glyptostrobus pensilis (Cupressaceae) is a critically endangered conifer native to China, Laos, and Vietnam, with only a few populations remaining in…”
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Genetic diversity and relationship of Hunan province of China local tree peonies based on SSR markers by Zhang, Min-Huan, Jin, Xiao-Ling, Wen, Ya-Feng, Shen, Shouyun, Xing, Wen, Wu, Sha, Lu, Jing-Hong, Ye, Ye

“…Paeonia sect. Moutan is a wide known ornamental plant in the world. The objective of this study was to provide the theoretical basis for scientific…”
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Therapeutic Orphan No More: Role for Clinical Pharmacology and Translational Science in Developing Therapeutics for Rare and Neglected Diseases by Ramamoorthy, Anuradha, Younis, Islam, Wen, Ya‐Feng, Mehanna, Mai, Giacomini, Kathleen M., Graaf, Piet H.

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Effect of governor vessel moxibustion (GVM) therapy with mild to moderate psoriasis: A randomized clinical trial by Sun, Dan, Feng, Wen-Ya, Mou, Jing-Kang, Chen, Lu, Zhao, Yi-Ding, Yan, Xiao-Ning, Li, Wen-Bin

“…It was hypothesized that governor vessel moxibustion (GVM) therapy may improve the course of mild to moderate psoriasis (PS) in patients. A randomized,…”
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Pharmacogenomic variabilities in geo-ancestral subpopulations and their clinical implications: Results of collaborations with Hmong in the United States by Sun, Boguang, Wen, Ya-Feng, Culhane-Pera, Kathleen A, Lo, Muaj, Straka, Robert J

“…Underrepresentation of subpopulations within geo-ancestral groups engaged in research can exacerbate health disparities and impair progress toward personalized…”
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The Identification of Novel CYP2D6 Variants in US Hmong: Results From Genome Sequencing and Clinical Genotyping by Wen, Ya Feng, Gaedigk, Andrea, Boone, Erin C, Wang, Wendy Y, Straka, Robert J

“…Hmong individuals represent a unique East Asian subpopulation in whom limited information concerning pharmacogenetic variation exists. The objectives of this…”
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