Search Results - "Wen, Shaojun"

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  1. 1

    Recent development of risk-prediction models for incident hypertension: An updated systematic review by Sun, Dongdong, Liu, Jielin, Xiao, Lei, Liu, Ya, Wang, Zuoguang, Li, Chuang, Jin, Yongxin, Zhao, Qiong, Wen, Shaojun

    Published in PloS one (30-10-2017)
    “…Hypertension is a leading global health threat and a major cardiovascular disease. Since clinical interventions are effective in delaying the disease…”
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    Journal Article
  2. 2

    Association study of WNK1 genetic variants and essential hypertension risk in the Northern Han Chinese in Beijing by Liu, Kuo, Liu, Jielin, Liu, Ya, Wang, Hao, Wang, Zuoguang, Liu, Jinghua, Wen, Shaojun

    Published in Frontiers in genetics (15-09-2023)
    “…Background: Essential hypertension (EH) is a complex disorder resulting from interaction of genetic and environmental factors. Lysine deficient protein kinase…”
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  3. 3

    Association of mitofusin 2 methylation and essential hypertension: a case-control study in a Chinese population by Jin, Fei, Li, Xiao, Wang, Zuoguang, Liu, Ya, Liu, Jielin, Sun, Dongdong, Jin, Yongxin, Wang, Shiqi, Wen, Shaojun, Wei, Yongxiang

    Published in Hypertension research (01-08-2018)
    “…Mitofusin 2 (Mfn2), a gene that negatively regulates the proliferation of vascular smooth muscle cells (VSMCs), is expressed at low levels in the VSMCs of…”
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  4. 4

    ADRB2 polymorphisms and dyslipidemia risk in Chinese hypertensive patients by Gu, Wei, Liu, Jilin, Wang, Zuoguang, Liu, Ya, Wen, Shaojun

    “…Single nucleotide polymorphisms (SNPs) within a β-adrenergic receptor (ADRB2) were shown to be related to lipid traits or hyperlipidemia in different…”
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  5. 5

    Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls by Liu, Kuo, Liu, Jielin, Huang, Yan, Liu, Ya, Lou, Yuqing, Wang, Zuoguang, Zhang, Hong, Yan, Shan, Li, Zhizhong, Wen, Shaojun

    Published in PloS one (28-09-2010)
    “…No clear consensus has been reached on the alpha-adducin polymorphism (Gly460Trp) and essential hypertension risk. We performed a meta-analysis in an effort to…”
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  6. 6

    Association of the −344T/C polymorphism in aldosterone synthase gene promoter with left ventricular structure in Chinese Han: A meta-analysis by Yin, Chengqian, Gu, Wei, Gao, Yun, Li, Zhao, Chen, Xuanzu, Li, Zhizhong, Wen, Shaojun

    “…No consensus view has been published on the relationship between the aldosterone synthase gene (CYP11B2) −344C/T polymorphism and left ventricular hypertrophy…”
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  7. 7

    Association between single-nucleotide polymorphisms in six hypertensive candidate genes and hypertension among northern Han Chinese individuals by Wang, Lijuan, Zhang, Bei, Li, Mei, Li, Chuang, Liu, Jielin, Liu, Ya, Wang, Zuoguang, Zhou, Jiapeng, Wen, Shaojun

    Published in Hypertension research (01-12-2014)
    “…Hypertension is one of the leading risk factors for mortality. The renin-angiotensin-aldosterone system (RAAS) is a potent and powerful mediator in the…”
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  8. 8

    Association of ECE1 gene polymorphisms and essential hypertension risk in the Northern Han Chinese: A case‒control study by Wang, Hao, Liu, Jielin, Liu, Kuo, Liu, Ya, Wen, Jie, Wang, Zuoguang, Wen, Shaojun

    Published in Molecular genetics & genomic medicine (01-04-2020)
    “…Background The ECE1 gene polymorphisms have been studied as a candidate gene in essential hypertension, but no consensus has been reached. To systematically…”
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  9. 9

    Simultaneous quantitative analysis of fasudil and its active metabolite in human plasma by liquid chromatography electro-spray tandem mass spectrometry by Chen, Huaying, Lin, Yang, Han, Min, Bai, Shugong, Wen, Shaojun

    “…A fast and sensitive method to quantify fasudil hydrochloride (FH) and its active metabolite hydroxyfasudil (M3) in human plasma using HPLC–MS/MS has been…”
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  10. 10
  11. 11

    A46G and C79G polymorphisms in the β2-adrenergic receptor gene ( ) and essential hypertension risk: a meta-analysis by Lou, Yuqing, Liu, Jinghua, Huang, Yan, Liu, Jielin, Wang, Zuoguang, Liu, Ya, Li, Zhizhong, Li, Yao, Xie, Yi, Wen, Shaojun

    Published in Hypertension research (01-11-2010)
    “…No consensus has been reached on the association between the β2-adrenergic receptor polymorphisms A46G and C79G and essential hypertension risk. We performed a…”
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  12. 12
  13. 13

    A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis by Gu, Wei, Liu, Jielin, Niu, Qiuli, Wang, Hao, Lou, Yuqing, Liu, Kuo, Wang, Lijuan, Wang, Zuoguang, Zhang, Jingmei, Wen, Shaojun

    Published in PloS one (28-12-2011)
    “…Numerous studies in Chinese populations have evaluated the association between the A-6G and A-20C polymorphisms in the promoter region of angiotensinogen gene…”
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  14. 14

    α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis by Liu, Kuo, Liu, Ya, Liu, Jielin, Wang, Zuoguang, Lou, Yuqing, Huang, Yan, Niu, Qiuli, Gu, Wei, Zhu, Xiaoling, Wen, Shaojun

    Published in Hypertension research (01-03-2011)
    “…No clear consensus has been reached on the α-adducin polymorphism (Gly460Trp) and essential hypertension (EH) risk in Chinese. We conducted a meta-analysis in…”
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  15. 15

    HSG/Mfn2 Gene Polymorphism and Essential Hypertension: a Case-Control Association Study in Chinese by Wang, Zuoguang, Liu, Ya, Liu, Jieling, Liu, Kuo, Wen, Jie, Wen, Shaojun, Wu, Zhaosu

    Published in Journal of Atherosclerosis and Thrombosis (01-01-2011)
    “…Aim: Hyperplasia suppressor gene/mitofusion-2 (HSG/Mfn2) is a hyperplasia suppressor gene and an essential component of mitochondrial fusion machinery;…”
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  16. 16

    Association between the angiotensinogen gene T174M polymorphism and hypertension risk in the Chinese population: a meta-analysis by Gu, Wei, Liu, Ya, Wang, Zuoguang, Liu, Kuo, Lou, Yuqing, Niu, Qiuli, Wang, Hao, Liu, Jinghua, Wen, Shaojun

    Published in Hypertension research (01-01-2012)
    “…No consensus has been reached on the association between the angiotensinogen gene polymorphism T174M and hypertension risk in the Chinese population. We…”
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  17. 17

    Association study of the β2-adrenergic receptor gene polymorphisms and hypertension in the Northern Han Chinese by Lou, Yuqing, Liu, Jielin, Li, Yao, Liu, Ya, Wang, Zuoguang, Liu, Kuo, Wu, Hai, Niu, Qiuli, Gu, Wei, Guo, Yanhong, Li, Zhizhong, Wen, Shaojun

    Published in PloS one (05-04-2011)
    “…The β2-adrenergic receptor (ADRB2) gene has been widely researched as a candidate gene for essential hypertension (EH), but no consensus has been reached in…”
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  18. 18

    A novel 5'-uncoding region -1248 A>G variation of mitofusin-2 gene is associated with hypertension in Chinese by Wang, Zuoguang, Liu, Ya, Liu, Jieling, Niu, Qiuli, Wen, Jie, Wen, Shaojun, Wu, Zhaosu

    Published in Yonsei medical journal (01-05-2013)
    “…Mitofusin2 gene (Mfn2, also named Hyperplasia suppressive gene, HSG) is very important in the origin and development of hypertension. However, the mechanism of…”
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  19. 19

    E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population by Wang, Zuoguang, Liu, Ya, Liu, Jieling, Liu, Kuo, Lou, Yuqin, Wen, Jie, Niu, Qiuli, Wen, Shaojun, Wu, Zhaosu

    Published in BMC genetics (27-08-2010)
    “…Genetic variation is thought to contribute to the etiology of hypertension, and E-selectin is a candidate essential hypertension-associated gene. This study…”
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  20. 20

    GW27-e0044 ADRB2 Polymorphisms and Dyslipidemia Risk in Chinese Hypertensive Patients by Wei, Gu, Wen, Shaojun

    “…[...]haplotype analysis showed that the TAC haplotype carrying frequent alleles of the three SNPs played a reduced role in hypertriglyceridemia risk and the…”
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