Search Results - "Wen, Shaojun"
-
1
Recent development of risk-prediction models for incident hypertension: An updated systematic review
Published in PloS one (30-10-2017)“…Hypertension is a leading global health threat and a major cardiovascular disease. Since clinical interventions are effective in delaying the disease…”
Get full text
Journal Article -
2
Association study of WNK1 genetic variants and essential hypertension risk in the Northern Han Chinese in Beijing
Published in Frontiers in genetics (15-09-2023)“…Background: Essential hypertension (EH) is a complex disorder resulting from interaction of genetic and environmental factors. Lysine deficient protein kinase…”
Get full text
Journal Article -
3
Association of mitofusin 2 methylation and essential hypertension: a case-control study in a Chinese population
Published in Hypertension research (01-08-2018)“…Mitofusin 2 (Mfn2), a gene that negatively regulates the proliferation of vascular smooth muscle cells (VSMCs), is expressed at low levels in the VSMCs of…”
Get full text
Journal Article -
4
ADRB2 polymorphisms and dyslipidemia risk in Chinese hypertensive patients
Published in Clinical and experimental hypertension (1993) (17-02-2017)“…Single nucleotide polymorphisms (SNPs) within a β-adrenergic receptor (ADRB2) were shown to be related to lipid traits or hyperlipidemia in different…”
Get full text
Journal Article -
5
Alpha-adducin Gly460Trp polymorphism and hypertension risk: a meta-analysis of 22 studies including 14303 cases and 15961 controls
Published in PloS one (28-09-2010)“…No clear consensus has been reached on the alpha-adducin polymorphism (Gly460Trp) and essential hypertension risk. We performed a meta-analysis in an effort to…”
Get full text
Journal Article -
6
Association of the −344T/C polymorphism in aldosterone synthase gene promoter with left ventricular structure in Chinese Han: A meta-analysis
Published in Clinical and experimental hypertension (1993) (18-08-2017)“…No consensus view has been published on the relationship between the aldosterone synthase gene (CYP11B2) −344C/T polymorphism and left ventricular hypertrophy…”
Get full text
Journal Article -
7
Association between single-nucleotide polymorphisms in six hypertensive candidate genes and hypertension among northern Han Chinese individuals
Published in Hypertension research (01-12-2014)“…Hypertension is one of the leading risk factors for mortality. The renin-angiotensin-aldosterone system (RAAS) is a potent and powerful mediator in the…”
Get full text
Journal Article -
8
Association of ECE1 gene polymorphisms and essential hypertension risk in the Northern Han Chinese: A case‒control study
Published in Molecular genetics & genomic medicine (01-04-2020)“…Background The ECE1 gene polymorphisms have been studied as a candidate gene in essential hypertension, but no consensus has been reached. To systematically…”
Get full text
Journal Article -
9
Simultaneous quantitative analysis of fasudil and its active metabolite in human plasma by liquid chromatography electro-spray tandem mass spectrometry
Published in Journal of pharmaceutical and biomedical analysis (05-06-2010)“…A fast and sensitive method to quantify fasudil hydrochloride (FH) and its active metabolite hydroxyfasudil (M3) in human plasma using HPLC–MS/MS has been…”
Get full text
Journal Article -
10
Expert consensus on diagnosis and treatment of adult mental stress induced hypertension in China (2022 revision): Part A
Published in Heart and mind (Mumbai, India) (01-04-2022)“…Mental stress has been recognized as an essential risk factor for hypertension. Therefore, experts specializing in cardiology, psychiatry, and Traditional…”
Get full text
Journal Article -
11
A46G and C79G polymorphisms in the β2-adrenergic receptor gene ( ) and essential hypertension risk: a meta-analysis
Published in Hypertension research (01-11-2010)“…No consensus has been reached on the association between the β2-adrenergic receptor polymorphisms A46G and C79G and essential hypertension risk. We performed a…”
Get full text
Journal Article -
12
Expert Consensus on Diagnosis and Treatment of Adult Mental Stress-Induced Hypertension in China (2022 Revision): Part B
Published in Heart and mind (Mumbai, India) (01-07-2022)“…Abstract Mental stress has been recognized as an essential risk factor for hypertension. Therefore, experts specializing in cardiology, psychiatry, and…”
Get full text
Journal Article -
13
A-6G and A-20C polymorphisms in the angiotensinogen promoter and hypertension risk in Chinese: a meta-analysis
Published in PloS one (28-12-2011)“…Numerous studies in Chinese populations have evaluated the association between the A-6G and A-20C polymorphisms in the promoter region of angiotensinogen gene…”
Get full text
Journal Article -
14
α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis
Published in Hypertension research (01-03-2011)“…No clear consensus has been reached on the α-adducin polymorphism (Gly460Trp) and essential hypertension (EH) risk in Chinese. We conducted a meta-analysis in…”
Get full text
Journal Article -
15
HSG/Mfn2 Gene Polymorphism and Essential Hypertension: a Case-Control Association Study in Chinese
Published in Journal of Atherosclerosis and Thrombosis (01-01-2011)“…Aim: Hyperplasia suppressor gene/mitofusion-2 (HSG/Mfn2) is a hyperplasia suppressor gene and an essential component of mitochondrial fusion machinery;…”
Get full text
Journal Article -
16
Association between the angiotensinogen gene T174M polymorphism and hypertension risk in the Chinese population: a meta-analysis
Published in Hypertension research (01-01-2012)“…No consensus has been reached on the association between the angiotensinogen gene polymorphism T174M and hypertension risk in the Chinese population. We…”
Get full text
Journal Article -
17
Association study of the β2-adrenergic receptor gene polymorphisms and hypertension in the Northern Han Chinese
Published in PloS one (05-04-2011)“…The β2-adrenergic receptor (ADRB2) gene has been widely researched as a candidate gene for essential hypertension (EH), but no consensus has been reached in…”
Get full text
Journal Article -
18
A novel 5'-uncoding region -1248 A>G variation of mitofusin-2 gene is associated with hypertension in Chinese
Published in Yonsei medical journal (01-05-2013)“…Mitofusin2 gene (Mfn2, also named Hyperplasia suppressive gene, HSG) is very important in the origin and development of hypertension. However, the mechanism of…”
Get full text
Journal Article -
19
E-selectin gene polymorphisms are associated with essential hypertension: a case-control pilot study in a Chinese population
Published in BMC genetics (27-08-2010)“…Genetic variation is thought to contribute to the etiology of hypertension, and E-selectin is a candidate essential hypertension-associated gene. This study…”
Get full text
Journal Article -
20
GW27-e0044 ADRB2 Polymorphisms and Dyslipidemia Risk in Chinese Hypertensive Patients
Published in Journal of the American College of Cardiology (18-10-2016)“…[...]haplotype analysis showed that the TAC haplotype carrying frequent alleles of the three SNPs played a reduced role in hypertriglyceridemia risk and the…”
Get full text
Journal Article