Search Results - "Wen, Jinlan"
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In vivo anti-hyperuricemia and anti-gouty arthritis effects of the ethanol extract from Amomumvillosum Lour
Published in Biomedicine & pharmacotherapy (01-05-2023)“…The incidence of hyperuricemia and gout has been increasing year by year, and it is showing a younger trend. However, the first-line drugs currently used for…”
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Hybrid molecules of scutellarein and 3, 5, 6-trimethylpyrazine-2-formic acid linked with polar amino acid for ischemic stroke
Published in Medicinal chemistry research (01-06-2022)“…Scutellarin has been found to possess a certain protective activity against oxidative damage, and scutellarein has been proved to be the main absorption…”
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Dynamic membranes with sparse nanofibers as the skeletons yield better and more stable effluent quality without sacrificing the flux in bioreactors
Published in Journal of membrane science (15-05-2022)“…Previous studies found that the inhabitation of filamentous bacteria on the support materials with large apertures in dynamic membrane bioreactor (DMBR) could…”
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Atomic insights into the mechanism of trace water influence on lipase catalysis in organic media
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-05-2023)“…[Display omitted] •Effect of water on lipase activity was investigated by experiments and simulations.•Water content in the micro-water organic system is…”
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Synthesis and bioevaluation of Scutellarein-Tertramethylpyrazine hybrid molecules for the treatment of ischemic stroke
Published in Bioorganic chemistry (01-01-2024)“…Ischemic stroke caused by insufficient blood supply to the brain may produce a sequence of cascade reactions, leading to oxidative stress and ultimately…”
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Design, synthesis and bioevaluation of 1,2,4-thiadiazolidine-3,5-dione derivatives as potential GSK-3β inhibitors for the treatment of Alzheimer's disease
Published in Bioorganic chemistry (01-05-2023)“…[Display omitted] •The kinase inhibitory activity of the selected compound 10a with better neuroprotective effect was 2.7 fold than that of Tideglusib.•Similar…”
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Discovery of 2-(isoxazol-5-yl)phenyl 3,4-dihydroxybenzoate as a potential inhibitor for the Wnt/β-catenin pathway
Published in Bioorganic chemistry (01-11-2022)“…[Display omitted] •S11 showed strong proliferation inhibition effect and excellent selectivity index against Wnt hyperactive cancer cells.•S11 could obvioudsly…”
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Research on Implementation Mechanism of Treatment-prevention Integration Under the Background of Constructing Integrated Service System
Published in Zhongguo quanke yixue (01-08-2024)“…Background The key task in China's medical and health field during the "14th Five-Year Plan" period is to realize treatment-prevention integration and innovate…”
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