Search Results - "Wen, Jiejun"

Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression by Fan, Ying, Yi, Zhengzi, D'Agati, Vivette D, Sun, Zeguo, Zhong, Fang, Zhang, Weijia, Wen, Jiejun, Zhou, Ting, Li, Ze, He, Li, Zhang, Qunzi, Lee, Kyung, He, John Cijiang, Wang, Niansong

“…To identify the factors mediating the progression of diabetic nephropathy (DN), we performed RNA sequencing of kidney biopsy samples from patients with early…”
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Ischemic Duration and Frequency Determines AKI-to-CKD Progression Monitored by Dynamic Changes of Tubular Biomarkers in IRI Mice by Dong, Yang, Zhang, Qunzi, Wen, Jiejun, Chen, Teng, He, Li, Wang, Yiyun, Yin, Jianyong, Wu, Rui, Xue, Rui, Li, Shiqi, Fan, Ying, Wang, Niansong

“…Ischemia reperfusion injury (IRI) is one of the most common causes of acute kidney injury (AKI). However, the pathogenesis and biomarkers predicting the…”
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Wnt5a promotes renal tubular inflammation in diabetic nephropathy by binding to CD146 through noncanonical Wnt signaling by Li, Xiaomei, Wen, Jiejun, Dong, Yang, Zhang, Qunzi, Guan, Jian, Liu, Feng, Zhou, Ting, Li, Ze, Fan, Ying, Wang, Niansong

“…Immune and inflammatory factors have emerged as key pathophysiological mechanisms in the progression of diabetic renal injury. Noncanonical Wnt5a signaling…”
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Inhibition of Reticulon-1A-Mediated Endoplasmic Reticulum Stress in Early AKI Attenuates Renal Fibrosis Development by Fan, Ying, Xiao, Wenzhen, Lee, Kyung, Salem, Fadi, Wen, Jiejun, He, Li, Zhang, Jing, Fei, Yang, Cheng, Dongsheng, Bao, Hongda, Liu, Yumei, Lin, Fujun, Jiang, Gengru, Guo, Zhiyong, Wang, Niansong, He, John Cijiang

“…Several animal studies have shown an important role for endoplasmic reticulum (ER) stress in AKI, whereas human studies are lacking. We recently reported that…”
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Pifithrin-α ameliorates glycerol induced rhabdomyolysis and acute kidney injury by reducing p53 activation by Yuqiang, Chen, Lisha, Zhang, Jiejun, Wen, Qin, Xue, Niansong, Wang

“…Rhabdomyolysis is a series of symptoms caused by the dissolution of striped muscle, and acute kidney injury (AKI) is a potential complication of severe…”
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Rtn1a-Mediated Endoplasmic Reticulum Stress in Podocyte Injury and Diabetic Nephropathy by Fan, Ying, Zhang, Jing, Xiao, Wenzhen, Lee, Kyung, Li, Zhengzhe, Wen, Jiejun, He, Li, Gui, Dingkun, Xue, Rui, Jian, Guihua, Sheng, Xiaohua, He, John Cijiang, Wang, Niansong

“…We previously reported a critical role of reticulon (RTN) 1A in mediating endoplasmic reticulum (ER) stress in kidney tubular cells and the expression of RTN1A…”
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Expression of Endothelial Cell Injury Marker Cd146 Correlates with Disease Severity and Predicts the Renal Outcomes in Patients with Diabetic Nephropathy by Fan, Ying, Fei, Yang, Zheng, Li, Wang, Jiemin, Xiao, Wenzhen, Wen, Jiejun, Xu, Yanping, Wang, Yiyun, He, Li, Guan, Jian, Wei, Jia, He, John Cijiang, Wang, Niansong

“…Background/Aims: Glomerular endothelial cell injury plays a crucial role in the development of diabetic nephropathy (DN). CD146, an endothelial marker, was…”
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Cardiac-specific renalase overexpression alleviates CKD-induced pathological cardiac remodeling in mice by Wang, Yi, Bai, Linnan, Wen, Jiejun, Zhang, Fangfei, Gu, Sijie, Wang, Feng, Yin, Jianyong, Wang, Niansong

“…CKD-induced pathological cardiac remodeling is characterized by myocardial hypertrophy and cardiac fibrosis. The available therapeutic options are limited, it…”
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Spatial Modulation Scheme With Low-Complexity Detection Algorithms by Jiang, Yang, Wang, Yuanlu, Wen, Jiejun, Shao, Mingxing, Li, Yibo

“…In this letter, two sphere-decoding (SD) algorithms for spatial modulation (SM) are proposed to reduce the computational complexity of maximum-likelihood (ML)…”
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Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy by He, Li, Fan, Ying, Xiao, Wenzhen, Chen, Teng, Wen, Jiejun, Dong, Yang, Wang, Yiyun, Li, Shiqi, Xue, Rui, Zheng, Liyang, He, John Cijiang, Wang, Niansong

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Engineering enhancement of the immune response to HBV DNA vaccine in mice by the use of LIGHT gene adjuvant by Zhang, Yali, Jiang, Wenzheng, Fan, Yan, Wen, Jiejun, Hao, Wenli, Qian, Min

“…DNA vaccines could induce protective immune responses in several animal models. Many strategies have been employed to improve the effect of nucleic acid…”
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Dl-3-n-butylphthalide pretreatment attenuates renal ischemia/reperfusion injury by Dong, Yang, Yin, Jianyong, Chen, Teng, Wen, Jiejun, Zhang, Qunzi, Li, Xiaomei, Lin, Wenjun, Liu, Feng, Fan, Ying, Wang, Niansong

“…Renal ischemia reperfusion injury (IRI) has become a growing concern in clinical practice with high morbidity and mortality rates. There is currently no…”
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Noncanonical Wnt5a/CD146 Signaling Drives Renal Fibrosis by Activating Transcriptional Factor Snail in AKI: PO0407 by Li, Xiaomei, Wen, Jiejun, Jia, Junjie, Zhang, Qunzi, Zhou, Ting, Fan, Ying, Wang, Niansong

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Sitagliptin ameliorates renal tubular injury in diabetic kidney disease via STAT3‐dependent mitochondrial homeostasis through SDF‐1α/CXCR4 pathway by Zhang, Qunzi, He, Li, Dong, Yang, Fei, Yang, Wen, Jiejun, Li, Xiaomei, Guan, Jian, Liu, Feng, Zhou, Ting, Li, Ze, Fan, Ying, Wang, Niansong

“…Mitochondrial abnormalities play critical roles in diabetic tubular injury progression. Dipeptidyl peptidase‐4 (DPP4) inhibitors are widely used…”
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Nicotinamide retains Klotho expression and ameliorates rhabdomyolysis-induced acute kidney injury by Lin, Wenjun, Wu, Xianfeng, Wen, Jiejun, Fei, Yang, Wu, Junnan, Li, Xiaomei, Zhang, Qunzi, Dong, Yang, Xu, Tao, Fan, Ying, Wang, Niansong

“…•Nicotinamide ameliorates rhabdomyolysis-induced acute kidney injury•Nicotinamide blocks the recruitment of nuclear factor kappa B and transcriptional…”
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Erratum. Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression. Diabetes 2019;68:2301-2314 by Fan, Ying, Yi, Zhengzi, D'Agati, Vivette D, Sun, Zeguo, Zhong, Fang, Zhang, Weijia, Wen, Jiejun, Zhou, Ting, Li, Ze, He, Li, Zhang, Qunzi, Lee, Kyung, He, John Cijiang, Wang, Niansong

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Co-delivery of LIGHT expression plasmid enhances humoral and cellular immune responses to HIV-1 Nef in mice by Wen, Jiejun, Hao, Wenli, Fan, Yan, Du, Jiani, Du, Bing, Qian, Min, Jiang, Wenzheng

“…The immunogenicity and efficacy of a DNA vaccine can be greatly enhanced when a gene adjuvant is used. LIGHT, a member of TNF superfamily, can function as a…”
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Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy by He, Li, Fan, Ying, Xiao, Wenzhen, Chen, Teng, Wen, Jiejun, Dong, Yang, Wang, Yiyun, Li, Shiqi, Xue, Rui, Zheng, Liyang, He, John Cijiang, Wang, Niansong

“…Hyperuricemia contributes to kidney tubular injury and kidney fibrosis. However, the underlying mechanism remains unclear. Here we examined the role of RTN1A,…”
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Improvement in efficacy of DNA vaccine encoding HIV-1 Vif by LIGHT gene adjuvant by Du, Jiani, Wu, Xiaoyu, Long, Fengying, Wen, Jiejun, Hao, Wenli, Chen, Ran, Kong, Xiaobo, Qian, Min, Jiang, Wenzheng

“…DNA vaccine can induce the prolonged immune responses against the encoded antigen with the appropriate adjuvant. To study the immunogenicity of the HIV-1 vif…”
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