Search Results - "Wen, Guilan"

The anti-inflammatory effect of arsenic trioxide effectively mitigates the pathogenic process in local chickens with avian leukosis by Wen, Anlin, Wang, Jianjun, Deng, Qiaomu, Ren, Tao, Yang, Jian, Wen, Guilan, Ou, Deyuan

“…Arsenic trioxide (ATO) is a classic first-line treatment for acute promyelocytic leukemia (APL). An increasing number of studies regarding the use of ATO in…”
Get full text

Enhancing Rumen Fermentation and Bacteria Community in Sika Deer ( Cervus nippon ) through Varying Levels of Dragon Fruit Peel Polyphenolic Extract: An In Vitro Study by Ban, Chao, Tian, Xingzhou, Lu, Qi, Lounglawan, Pipat, Wen, Guilan

“…The aim of this study is to investigate the effect of dragon fruit peel polyphenolic extract (DFPE) on gas production, rumen fermentation, and bacterial…”
Get full text

Antibacterial activity and mechanism of luteolin isolated from Lophatherum gracile Brongn. against multidrug-resistant Escherichia coli by Ding, Yahao, Wen, Guilan, Wei, Xingke, Zhou, Hao, Li, Chunjie, Luo, Zhengqin, Ou, Deyuan, Yang, Jian, Song, Xuqin

“…Infections caused by multidrug-resistant (MDR) bacteria have become a major challenge for global healthcare systems. The search for antibacterial compounds…”
Get full text

Adjuvant Effects of Deleting Hypervariable Domains of FliC of Escherichia coli Nissle 1917 by Li, Shuang, Deng, Yongjun, Ou, Bingming, Wen, Ming, Yang, Ying, Wen, Guilan

“…Bacterial flagellin (FliC) can be used as a TLR5 ligand-like adjuvant. However, the sequences of hypervariable regions(HVR) of FliC from different bacteria…”
Get full text

Interplay between acetylation and ubiquitination controls PSAT1 protein stability in lung adenocarcinoma by Liu, Yuhan, Xun, Wenze, Zhao, Tao, Huang, Menglin, Sun, Longhua, Wen, Guilan, Kang, Xiuhua, Wang, Jianbin, Han, Tianyu

“…Serine is essential to maintain maximal growth and proliferation of cancer cells by providing adequate intermediate metabolites and energy. Phosphoserine…”
Get full text

Transcriptional responses of LSm14A after infection of blue eggshell layers with Newcastle disease viruses by TIAN, Lang, WU, Changhua, WEN, Guilan, LI, Changhong

“…LSm14A is a key innate immunity component of processing body (P-body) that mediates interferon-β (IFN-β) signaling by viral RNA. This is the first study to…”
Get full text

Molecular Characterization of Three Porcine Reproductive and Respiratory Syndrome Virus Isolates and Their Susceptibility to Antiviral Drugs by Hongxia Hu, Xian Zhang, Hansong Zhang, Guilan Wen, Chao Tong, Xiaoliang Li, Weihuan Fang

“…Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most common swine pathogens that cause severe economic losses to the pig industry…”
Get full text

Structure and biological activity in vitro of Flagellin and its mutants from Escherichia coli Nissle 1917 by Li, Shuang, Wen, Ming, Wen, Guilan, Yang, Ying

“…Bacterial flagellin is a potent immunomodulatory agent. Previously, we successfully obtained flagellin from Escherichia coli Nissle 1917 (FliC EcN ) and…”
Get full text

The deformation modes and transferability during low-cycle fatigue of Mg and Mg–3Y alloy by Li, Tianjiao, Zheng, Jiang, Shou, Haoge, Shi, Rong, Zhang, Yongfa, Wen, Guilan, Huang, Kang, Yin, Dongdi, Rao, Jinsong

“…Mg–Y alloys show distinctly different slip/twinning activity under quasi-static monotonic loading at room temperature compared with pure Mg, as extensively…”
Get full text

One-step hydrothermal synthesis and characterization of Cu-doped TiO2 nanoparticles/nanobucks/nanorods with enhanced photocatalytic performance under simulated solar light by Zhu, Xiaodong, Wen, Guilan, Liu, Hui, Han, Shihu, Chen, Shanhua, Kong, Qingquan, Feng, Wei

“…Cu–TiO 2 and pure TiO 2 were prepared by a facile one-step hydrothermal method and the obtained photocatalysts were tested by XRD, Raman, BET, XPS, DRS, PL,…”
Get full text

Effect of First-Line Serplulimab vs Placebo Added to Chemotherapy on Survival in Patients With Extensive-Stage Small Cell Lung Cancer: The ASTRUM-005 Randomized Clinical Trial by Cheng, Ying, Han, Liang, Wu, Lin, Chen, Jun, Sun, Hongmei, Wen, Guilan, Ji, Yinghua, Dvorkin, Mikhail, Shi, Jianhua, Pan, Zhijie, Shi, Jinsheng, Wang, Xicheng, Bai, Yuansong, Melkadze, Tamar, Pan, Yueyin, Min, Xuhong, Viguro, Maksym, Li, Xingya, Zhao, Yanqiu, Yang, Junquan, Makharadze, Tamta, Arkania, Ekaterine, Kang, Wenying, Wang, Qingyu, Zhu, Jun

“…IMPORTANCE: Programmed cell death ligand 1 inhibitors combined with chemotherapy has changed the approach to first-line treatment in patients with…”
Get full text

The TLR4/ERK/PD‑L1 axis may contribute to NSCLC initiation by Kang, Xiuhua, Li, Penghui, Zhang, Chuibin, Zhao, Yunshan, Hu, Huoli, Wen, Guilan

“…Infection and inflammation serve an important role in tumor development. Toll‑like receptor 4 (TLR4) is a pivotal component of the innate and adaptive immune…”
Get full text

Quantitative investigation on the deformation modes and cracking behavior during cyclic torsional loading of extruded pure Mg and Mg‐3Y alloy by He, Liuyong, Wen, Guilan, Zheng, Jiang, Shi, Rong, Xia, Lihong, Li, Tianjiao, Jiang, Bin

“…This study explores the effect of adding 3 wt.% Y to pure magnesium (Mg) on its mechanical behavior under cyclic torsional loadings at room temperature. The…”
Get full text

MicroRNA‐448 overexpression inhibits fibroblast proliferation and collagen synthesis and promotes cell apoptosis via targeting ABCC3 through the JNK signaling pathway by Xu, Feihong, Xu, Fei, Xie, Shiguang, Zuo, Wei, Wen, Guilan, Zhao, Tiantian, Wan, Xuan

“…Idiopathic pulmonary fibrosis (IPF) is a condition that results in the progressive deterioration of lung function with poor prognosis. The current study is…”
Get full text

Cryptotanshinone inhibits cellular proliferation of human lung cancer cells through downregulation of IGF-1R/PI3K/Akt signaling pathway by Zhang, Jingtao, Wen, Guilan, Sun, Longhua, Yuan, Wenxin, Wang, Ran, Zeng, Qinghua, Zhang, Guangyi, Yu, Bentong

“…Lung cancer is one of the most commonly diagnosed malignancies worldwide. Cryptotanshinone (CPT) is a diterpene quinone compound extracted from natural plants…”
Get full text

Parthenolide inhibits human lung cancer cell growth by modulating the IGF‑1R/PI3K/Akt signaling pathway by Sun, Longhua, Yuan, Wenxin, Wen, Guilan, Yu, Bentong, Xu, Fei, Gan, Xin, Tang, Jianjun, Zeng, Qinghua, Zhu, Lanlan, Chen, Chuanhui, Zhang, Wei

“…Lung cancer is the leading cause of cancer-associated mortality worldwide. Parthenolide (PTL), a natural product extracted from the plant Tanacetum parthenium,…”
Get full text

Serplulimab vs. placebo combined with chemotherapy as first-line treatment for extensive-stage small-cell lung cancer: Extended follow-up results and patient-reported outcomes from the international phase 3 ASTRUM-005 study by Cheng, Ying, Han, Liang, Wu, Lin, Chen, Jun, Sun, Hongmei, Wen, Guilan, Ji, Yinghua, Zimina, Anastasia V., Shi, Jianhua, Pan, Zhijie, Shi, Jinsheng, Wang, Xicheng, Bai, Yuansong, Melkadze, Tamar, Pan, Yueyin, Min, Xuhong, Viguro, Maksym, Li, Jing, Wang, Qingyu, Zhu, Jun

“…8100 Background: ASTRUM-005 is a randomized, double-blind, phase 3 trial comparing efficacy and safety of serplulimab (a novel anti-PD-1 antibody) plus…”
Get full text

Serplulimab, a novel anti-PD-1 antibody, plus chemotherapy versus chemotherapy alone as first-line treatment for extensive-stage small-cell lung cancer: An international randomized phase 3 study by Cheng, Ying, Han, Liang, Wu, Lin, Chen, Jun, Sun, Hongmei, Wen, Guilan, Ji, Yinghua, Dvorkin, Mikhail, Shi, Jianhua, Pan, Zhijie, Shi, Jinsheng, Wang, Xicheng, Bai, Yuansong, Melkadze, Tamar, Pan, Yueyin, Min, Xuhong, Viguro, Maksym, Xu, Yan, Wang, Qingyu, Zhu, Jun

“…8505 Background: Monoclonal antibodies against programmed death-ligand 1 (PD-L1) have been approved for the first-line treatment of extensive-stage small-cell…”
Get full text

SHR-1701, a bifunctional fusion protein targeting PD-L1 and TGF-β, for advanced NSCLC with EGFR mutations: Data from a multicenter phase 1 study by Shi, Meiqi, Chen, Jianhua, Li, KunYan, Fang, Yong, Wen, Guilan, Li, Xingya, Liu, Yunpeng, Sun, Yuping, Zhu, Bo, Lin, Lizhu, Shi, Yuankai, Wang, Linna, Yang, Junqin, Liu, Pan, Feng, Jifeng

“…Abstract only 9055 Background: Despite the development of targeted therapies for advanced NSCLC harboring EGFR mutations ( EGFR+), acquired resistance remains…”
Get full text

Cryptotanshinone inhibits cellular proliferation of human lung cancer cells through downregulation ofIGF-1R/PI3K/Akt signaling pathway by Zhang, Jingtao, Wen, Guilan, Sun, Longhua, Yuan, Wenxin, Wang, Ran, Zeng, Qinghua, Zhang, Guangyi, Yu, Bentong

“…Lung cancer is one of the most commonly diagnosed malignancies worldwide. Cryptotanshinone (CPT) is a diterpene quinone compound extracted from natural plants…”
Get full text