Search Results - "Wempe, M.F"
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The effect of STAT3 inhibition on status epilepticus and subsequent spontaneous seizures in the pilocarpine model of acquired epilepsy
Published in Neurobiology of disease (01-02-2014)“…Abstract Pilocarpine-induced status epilepticus (SE), which results in temporal lobe epilepsy (TLE) in rodents, activates the JAK/STAT pathway. In the current…”
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EPS7.2 Pharmacokinetics of oral MAC antibiotics in cystic fibrosis
Published in Journal of cystic fibrosis (01-06-2017)Get full text
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L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia
Published in Leukemia (01-06-2015)“…The altered metabolism of cancer cells is a treasure trove to discover new antitumoral strategies. The gene ( SLC7A5 ) encoding system L amino-acid transporter…”
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Long-term storage of lyophilized liposomal formulations
Published in Journal of pharmaceutical sciences (01-12-2014)“…Because aqueous liposomal formulations containing multiply unsaturated lipids are susceptible to chemical degradation, these formulations are often…”
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L-type amino-acid transporter 1
Published in Leukemia (01-06-2015)“…The altered metabolism of cancer cells is a treasure trove to discover new antitumoral strategies. The gene (SLC7A5) encoding system L amino-acid transporter 1…”
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Lyophilization of a triply unsaturated phospholipid: Effects of trace metal contaminants
Published in European journal of pharmaceutics and biopharmaceutics (01-10-2013)“…As liquid liposomal formulations are prone to chemical degradation and aggregation, these formulations often require freeze drying (e.g., lyophilization) to…”
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Quaternary ammonium ions can externally block voltage-gated K + channels. Establishing a theoretical and experimental model that predicts KDs and the selectivity of K + over Na + ions
Published in Journal of molecular structure (02-05-2001)“…The physicochemical basis for the high ion selectivity of potassium channels is poorly understood. In the present studies, external blockade of cloned…”
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