Search Results - "Wemlinger, Scott M"

Impaired B cell function during viral infections due to PTEN-mediated inhibition of the PI3K pathway by Getahun, Andrew, Wemlinger, Scott M, Rudra, Pratyaydipta, Santiago, Mario L, van Dyk, Linda F, Cambier, John C

“…Transient suppression of B cell function often accompanies acute viral infection. However, the molecular signaling circuitry that enforces this…”
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Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer by Wemlinger, Scott M., Cambier, John C.

“…B lymphocytes have become a very popular therapeutic target in a number of autoimmune indications due to their newly appreciated roles, and approachability, in…”
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Preclinical Analysis of Candidate Anti-Human CD79 Therapeutic Antibodies Using a Humanized CD79 Mouse Model by Wemlinger, Scott M, Parker Harp, Chelsea R, Yu, Bo, Hardy, Ian R, Seefeldt, Matthew, Matsuda, Jennifer, Mingueneau, Michael, Spilker, Kerri A, Cameron, Thomas O, Larrick, James W, Getahun, Andrew, Cambier, John C

“…The BCR comprises a membrane-bound Ig that is noncovalently associated with a heterodimer of CD79A and CD79B. While the BCR Ig component functions to sense…”
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Soluble Antigen Arrays for Selective Desensitization of Insulin-Reactive B Cells by Leon, Martin A, Wemlinger, Scott M, Larson, Nicholas R, Ruffalo, Justin K, Sestak, Joshua O, Middaugh, C. Russell, Cambier, John C, Berkland, Cory

“…Autoimmune diseases are believed to be highly dependent on loss of immune tolerance to self-antigens. Currently, no treatments have been successful clinically…”
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