Search Results - "Welt, S"

Revision of the Subgenus Ochthomantis Frogs from Madagascar (Amphibia: Mantellidae) with the Description of Four Species and Resurrection of Mantidactylus catalai and M. poissoni by Rabibisoa, Nirhy H. C., Welt, Rachel S., Raxworthy, Christopher J.

“…The subgenus Ochthomantis is an obligate forest and stream-dwelling group of mantellid frogs, endemic to Madagascar, with six species currently recognized…”
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Trastuzumab and lapatinib modulation of HER2 tyrosine/threonine phosphorylation and cell signaling by Kostyal, D., Welt, R. S., Danko, J., Shay, T., Lanning, C., Horton, K., Welt, S.

“…Cell surface transmembrane signaling receptors EGFR, HER3, and HER4 are activated by ligand-binding-mediated dimerization and phosphorylation. In contrast,…”
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Dispersal, not vicariance, explains the biogeographic origin of iguanas on Madagascar by Welt, Rachel S., Raxworthy, Christopher J.

“…[Display omitted] •We test multiple hypotheses to explain the origin of iguanas on Madagascar.•We apply NGS and morphological data in a fossilized birth–death…”
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Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanized monoclonal antibody A33 by RITTER, Gerd, COHEN, Leonard S, WILLIAMS, Clarence JR, RICHARDS, Elizabeth C, OLD, Lloyd J, WELT, Sydney

“…Mouse monoclonal antibody A33 (mAb A33) recognizes a M(r) 43,000 cell surface glycoprotein (designated A33) expressed in human colonic epithelium and colon…”
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Confinement Behavior of Rectangular Reinforced Concrete Prisms Simulating Wall Boundary Elements by Welt, Travis S, Massone, Leonardo M, LaFave, James M, Lehman, Dawn E, McCabe, Steven L, Polanco, Pablo

“…AbstractObservations following recent earthquakes, and from structural testing, indicate numerous brittle compression failures in reinforced concrete…”
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PET imaging of (86)Y-labeled anti-Lewis Y monoclonal antibodies in a nude mouse model: comparison between (86)Y and (111)In radiolabels by Lövqvist, A, Humm, J L, Sheikh, A, Finn, R D, Koziorowski, J, Ruan, S, Pentlow, K S, Jungbluth, A, Welt, S, Lee, F T, Brechbiel, M W, Larson, S M

“…Absorbed doses in (90)Y radioimmunotherapy are usually estimated by extrapolating from (111)In imaging data. PET using (86)Y (beta(+) 33%; half-life, 14.7 h)…”
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Phase I/II study of iodine 125-labeled monoclonal antibody A33 in patients with advanced colon cancer by Welt, S, Scott, A M, Divgi, C R, Kemeny, N E, Finn, R D, Daghighian, F, Germain, J S, Richards, E C, Larson, S M, Old, L J

“…A phase I/II study was designed to determine the maximum-tolerated dose (MTD) of iodine 125-labeled monoclonal antibody A33 (125I-mAb A33), its limiting organ…”
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Phase I/II radioimmunotherapy trial with iodine-131-labeled monoclonal antibody G250 in metastatic renal cell carcinoma by Divgi, C R, Bander, N H, Scott, A M, O'Donoghue, J A, Sgouros, G, Welt, S, Finn, R D, Morrissey, F, Capitelli, P, Williams, J M, Deland, D, Nakhre, A, Oosterwijk, E, Gulec, S, Graham, M C, Larson, S M, Old, L J

“…This Phase I/II radioimmunotherapy study was carried out to determine the maximum tolerated dose (MTD) and therapeutic potential of 131I-G250. Thirty-three…”
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A33scFv-cytosine deaminase: a recombinant protein construct for antibody-directed enzyme-prodrug therapy by DECKERT, P. M, RENNER, C, COHEN, L. S, JUNGBLUTH, A, RITTER, G, BERTINO, J. R, OLD, L. J, WELT, S

“…A recombinant fusion protein of colon carcinoma binding A33 single chain antibody with cytosine deaminase displayed specific antigen binding and enzyme…”
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Antibodies in the therapy of colon cancer by Welt, S, Ritter, G

“…Clinical research in antibody-based cancer therapy has been driven for many years by the prospect of identifying cell-surface antigens with sufficiently…”
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Antibody targeting in metastatic colon cancer: a phase I study of monoclonal antibody F19 against a cell-surface protein of reactive tumor stromal fibroblasts by Welt, S, Divgi, C R, Scott, A M, Garin-Chesa, P, Finn, R D, Graham, M, Carswell, E A, Cohen, A, Larson, S M, Old, L J

“…To define the toxicity, imaging, and biodistribution characteristics of iodine 131-labeled monoclonal antibody F19 (131I-mAbF19). MAbF19 recognizes the…”
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Relative therapeutic efficacy of (125)I- and (131)I-labeled monoclonal antibody A33 in a human colon cancer xenograft by Barendswaard, E C, Humm, J L, O'Donoghue, J A, Sgouros, G, Finn, R D, Scott, A M, Larson, S M, Welt, S

“…A33, a monoclonal antibody that targets colon carcinomas, was labeled with (125)I or (131)I and the relative therapeutic efficacy of the 2 radiolabeled species…”
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Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma by Divgi, C R, Welt, S, Kris, M, Real, F X, Yeh, S D, Gralla, R, Merchant, B, Schweighart, S, Unger, M, Larson, S M

“…Murine monoclonal antibody (MAb) 225 (IgG1) against the epidermal growth factor (EGF) receptor competitively blocks EGF binding and inhibits EGF-induced…”
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Specificity and biologic activities of novel anti-membrane IgM antibodies by Welt, Rachel S, Welt, Jonathan A, Kostyal, David, Gangadharan, Yamuna D, Raymond, Virginia, Welt, Sydney

“…The concept that the B-cell Receptor (BCR) initiates a driver pathway in lymphoma-leukemia has been clinically validated. Previously described unique BCR…”
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Phase I/II study of iodine 131-labeled monoclonal antibody A33 in patients with advanced colon cancer by Welt, S, Divgi, C R, Kemeny, N, Finn, R D, Scott, A M, Graham, M, Germain, J S, Richards, E C, Larson, S M, Oettgen, H F

“…A phase I/II study was designed to determine the maximum-tolerated dose (MTD) of iodine 131-labeled monoclonal antibody (mAb) A33 (131I-mAb A33) administered…”
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Analysis of population genetic structure and gene flow in an annual plant before and after a rapid evolutionary response to drought by Welt, Rachel S., Litt, Amy, Franks, Steven J.

“…Climate change can have widespread and devastating impacts, but little is known about the effects of this change on the genetics of natural populations. We…”
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Unrecognized species diversity and new insights into colour pattern polymorphism within the widespread Malagasy snake Mimophis (Serpentes: Lamprophiidae) by Ruane, Sara, Myers, Edward A., Lo, Kahmun, Yuen, Sara, Welt, Rachel S., Juman, Maya, Futterman, India, Nussbaum, Ronald A., Schneider, Gregory, Burbrink, Frank T., Raxworthy, Christopher J.

“…Although many wide-ranging taxa occur in Madagascar, phylogeographic studies for most of these species are still lacking. This is especially the case for…”
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Kinetic analysis of the interaction between the monoclonal antibody A33 and its colonic epithelial antigen by the use of an optical biosensor: A comparison of immobilisation strategies by Catimel, B, Nerrie, M, Lee, F.T, Scott, A.M, Ritter, G, Welt, S, Old, L.J, Burgess, A.W, Nice, E.C

“…The interaction between the humanised A33 monoclonal antibody and the corresponding F(ab)2′ or Fab′ fragments with the colonic epithelial A33 antigen, purified…”
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Antibody localization in human renal cell carcinoma: a phase I study of monoclonal antibody G250 by Oosterwijk, E, Bander, N H, Divgi, C R, Welt, S, Wakka, J C, Finn, R D, Carswell, E A, Larson, S M, Warnaar, S O, Fleuren, G J

“…To define the imaging and biodistribution characteristics of iodine 131-labeled monoclonal antibody (mAb) G250 (131I-mAbG250), which recognizes a cell-surface…”
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Optimizing the Sequence of Combination Therapy with Radiolabeled Antibodies and Fractionated External Beam by Ruan, Shutian, O'Donoghue, Joseph A, Larson, Steven M, Finn, Ronald D, Jungbluth, Achim, Welt, Sydney, Humm, John L

“…The purpose of this study was to determine the optimum sequence for combined modality therapy with radiolabeled antibodies and fractionated external beam…”
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