Search Results - "Welsh, Natalie J"

Functional assessment of glucocerebrosidase modulator efficacy in primary patient-derived macrophages is essential for drug development and patient stratification by Welsh, Natalie J, Gewinner, Christina A, Mistry, Kavita, Koglin, Mumta, Cooke, Juniebel, Butler, Matthew, Powney, Ben, Roberts, Malcolm, Staddon, James M, Schapira, Anthony H V

Get full text

Cycling around cell-cell adhesion with Rho GTPase regulators by McCormack, Jessica, Welsh, Natalie J, Braga, Vania M M

“…The formation and stability of epithelial adhesive systems, such as adherens junctions, desmosomes and tight junctions, rely on a number of cellular processes…”
Get full text

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at 16q11.2 and MAPT H1 loci by Soutar, Marc P M, Melandri, Daniela, O'Callaghan, Benjamin, Annuario, Emily, Monaghan, Amy E, Welsh, Natalie J, D'Sa, Karishma, Guelfi, Sebastian, Zhang, David, Pittman, Alan, Trabzuni, Daniah, Verboven, Anouk H A, Pan, Kylie S, Kia, Demis A, Bictash, Magda, Gandhi, Sonia, Houlden, Henry, Cookson, Mark R, Kasri, Nael Nadif, Wood, Nicholas W, Singleton, Andrew B, Hardy, John, Whiting, Paul J, Blauwendraat, Cornelis, Whitworth, Alexander J, Manzoni, Claudia, Ryten, Mina, Lewis, Patrick A, Plun-Favreau, Hélène

“…Parkinson's disease is a common incurable neurodegenerative disease. The identification of genetic variants via genome-wide association studies has…”
Get full text

Disruption of ER−mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis by Lau, Dawn H. W., Hartopp, Naomi, Welsh, Natalie J., Mueller, Sarah, Glennon, Elizabeth B., Mórotz, Gábor M., Annibali, Ambra, Gomez-Suaga, Patricia, Stoica, Radu, Paillusson, Sebastien, Miller, Christopher C. J.

“…Fronto-temporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are two related and incurable neurodegenerative diseases. Features of these diseases…”
Get full text

Cooperation of distinct Rac-dependent pathways to stabilise E-cadherin adhesion by Erasmus, Jennifer C., Welsh, Natalie J., Braga, Vania M.M.

“…The precise mechanisms via which Rac1 is activated by cadherin junctions are not fully known. In keratinocytes Rac1 activation by cadherin junctions requires…”
Get full text