Search Results - "Welsh, J A"
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Pathways and mechanisms linking dietary components to cardiometabolic disease: thinking beyond calories
Published in Obesity reviews (01-09-2018)“…Summary Calories from any food have the potential to increase risk for obesity and cardiometabolic disease because all calories can directly contribute to…”
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Sugars and adiposity: the long‐term effects of consuming added and naturally occurring sugars in foods and in beverages
Published in Obesity science & practice (01-10-2015)“…Summary Objective The aim of this study was to determine if the association with adiposity varies by the type (added vs. naturally occurring) and form (liquid…”
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3
Environmental tobacco smoke, genetic susceptibility, and risk of lung cancer in never-smoking women
Published in JNCI : Journal of the National Cancer Institute (01-12-1999)“…Exposure to environmental tobacco smoke (ETS) is considered to be a major lung cancer risk factor for never smokers. We investigated the hypothesis that…”
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Acute effects of force and vibration on finger blood flow
Published in Occupational and environmental medicine (London, England) (01-02-2006)“…Objectives: To investigate the effects of contact force at the finger on acute changes in finger circulation during exposure to vibration. Methods: Each of 10…”
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Sugar intake by type (added vs. naturally occurring) and physical form (liquid vs. solid) and its varying association with children's body weight, NHANES 2009–2014
Published in Pediatric obesity (01-04-2018)“…Summary Background Sugars and their primary dietary sources (milk, fruits, sweetened foods and beverages) are associated, in different ways, with a range of…”
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Mutational hot spot in the p53 gene in human hepatocellular carcinomas
Published in Nature (London) (01-04-1991)Get full text
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Frequent Mutation of the p53 Gene in Human Esophageal Cancer
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1990)“…Sequence alterations in the p53 gene have been detected in human tumors of the brain, breast, lung, and colon, and it has been proposed that p53 mutations…”
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Oxidative Stress and p53 Mutations in the Carcinogenesis of Iron Overload-Associated Hepatocellular Carcinoma
Published in JNCI : Journal of the National Cancer Institute (07-11-2001)“…To eliminate any false-positive results, confirmatory standard automated sequencing was performedon each mutation. Del [H11505] deletion; Ins [H11505]…”
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Longitudinal structure in the CHAMP electron densities and their implications for global ionospheric modeling
Published in Radio science (06-03-2010)“…Detailed examination of the electron densities in the equatorial ionosphere observed by the CHAMP satellite at ∼400 km and mapped for a fixed local time has…”
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Mutational hotspot in the p53 gene in human hepatocellular carcinomas
Published in Nature (London) (04-04-1991)“…Human hepatocellular carcinomas (HCC) from patients in Qidong, an area of high incidence in China, in which both hepatitis B virus and aflatoxin B1 are risk…”
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p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines
Published in Carcinogenesis (New York) (01-05-1993)“…A G:C-->T:A mutational hotspot at codon 249 of the p53 tumor suppressor gene has previously been identified in hepatocellular carcinoma (HCC) of patients from…”
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Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene?
Published in Human & experimental toxicology (01-01-2007)“…Mutation analysis methods have increased in variety during the past years. High-throughput microarray methods have especially increased in popularity. However,…”
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p53 mutations in human immortalized epithelial cell lines
Published in Carcinogenesis (New York) (01-05-1993)“…Although rodent cells have been immortalized following transfection with a mutant p53 gene, the role of p53 in the immortalization of human cells is unknown…”
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Genetic analysis of human esophageal tumors from two high incidence geographic areas: frequent p53 base substitutions and absence of ras mutations
Published in Cancer research (Chicago, Ill.) (01-08-1991)“…Esophageal squamous cell carcinoma (ESC) samples from patients residing in Uruguay and in Normandy, France, where alcoholic beverages and tobacco smoke are…”
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Gender comparisons in human lung cancer: analysis of p53 mutations, anti-p53 serum antibodies and C-erbB-2 expression
Published in Carcinogenesis (New York) (01-05-1995)“…Little is known about the molecular mechanisms of lung carcinogenesis in women. We initiated an investigation of the role of gender in pulmonary carcinogenesis…”
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An aflatoxin-associated mutational hotspot at codon 249 in the p53 tumor suppressor gene occurs in hepatocellular carcinomas from Mexico
Published in Carcinogenesis (New York) (01-05-1996)“…The p53 tumor suppressor gene is commonly mutated in human hepatocellular carcinoma (HCC). The most frequent mutation in HCC in populations exposed to a high…”
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Clinical Utility of Reliable Digit Span in Assessing Effort in Children and Adolescents with Epilepsy
Published in Archives of clinical neuropsychology (01-11-2012)“…The assessment of effort is an important aspect of a comprehensive neuropsychological evaluation, as this can significantly impact data interpretation. While…”
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Integrity of p53 in hepatitis B x antigen-positive and -negative hepatocellular carcinomas
Published in Cancer research (Chicago, Ill.) (01-02-1997)“…Inactivation of the tumor suppressor p53 seems to be important to the pathogenesis of hepatocellular carcinoma (HCC) associated with chronic hepatitis B virus…”
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p53 and kirsten-ras mutations in human mesothelioma cell lines
Published in Cancer research (Baltimore) (01-05-1992)“…Twenty cell lines from 17 individuals with malignant mesothelioma have been examined for p53 alterations by direct sequencing of genomic DNA, by evaluation of…”
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Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners
Published in The Lancet (British edition) (07-03-1992)“…Radon increases the risk of lung cancer in smoking and non-smoking underground miners. To investigate the mutational spectrum associated with exposure to high…”
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