Search Results - "Welniak, Lisbeth A."

Immunobiology of allogeneic hematopoietic stem cell transplantation by Welniak, Lisbeth A, Blazar, Bruce R, Murphy, William J

“…Allogeneic hematopoietic stem cell transplantation (HSCT) has evolved into an effective adoptive cellular immunotherapy for the treatment of a number of…”
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The Fourth International Workshop on Clinical Transplant Tolerance by Issa, Fadi, Strober, Samuel, Leventhal, Joseph R., Kawai, Tatsuo, Kaufman, Dixon B., Levitsky, Josh, Sykes, Megan, Mas, Valeria, Wood, Kathryn J., Bridges, Nancy, Welniak, Lisbeth A., Chandran, Sindhu, Madsen, Joren C., Nickerson, Peter, Demetris, Anthony J., Lakkis, Fadi G., Thomson, Angus W.

“…The International Workshop on Clinical Transplant Tolerance is a biennial meeting that aims to provide an update on the progress of studies of…”
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Providing researchers with online access to NHLBI biospecimen collections: The results of the first six years of the NHLBI BioLINCC program by Giffen, Carol A, Wagner, Elizabeth L, Adams, John T, Hitchcock, Denise M, Welniak, Lisbeth A, Brennan, Sean P, Carroll, Leslie E

“…The National Heart, Lung, and Blood Institute (NHLBI), within the United States' National Institutes of Health (NIH), established the Biologic Specimen and…”
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The National Heart, Lung, and Blood Institute‐funded Production Assistance for Cellular Therapies (PACT) program: Eighteen years of cell therapy by El Fiky, Ashraf, Ibenana, Laarni, Anderson, Robert, Hare, Joshua M., Khan, Aisha, Gee, Adrian P., Rooney, Cliona, McKenna, David H., Gold, Joseph, Kelley, Linda, Lundberg, Martha S., Welniak, Lisbeth A., Lindblad, Robert

“…The Production Assistance for Cellular Therapies (PACT) Program, is funded and supported by the US Department of Health and Human Services’ National Institutes…”
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Inhibition of Acute Graft-versus-Host Disease with Retention of Graft-versus-Tumor Effects by the Proteasome Inhibitor Bortezomib by Sun, Kai, Welniak, Lisbeth A., Panoskaltsis-Mortari, Angela, O'Shaughnessy, Matthew J., Liu, Haiyan, Barao, Isabel, Riordan, William, Sitcheran, Raquel, Wysocki, Christian, Serody, Jonathan S., Blazar, Bruce R., Sayers, Thomas J., Murphy, William J., Vitetta, Ellen S.

“…Graft-versus-host disease (GVHD) represents a major hurdle impeding the efficacy of allogeneic bone marrow transplantation (BMT). Bortezomib is a proteasome…”
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Suppression of Natural Killer Cell-Mediated Bone Marrow Cell Rejection by CD4⁺CD25⁺ Regulatory T Cells by Barao, Isabel, Hanash, Alan M., Hallett, William, Welniak, Lisbeth A., Sun, Kai, Redelman, Doug, Blazar, Bruce R., Levy, Robert B., Murphy, William J.

“…Naturally occurring CD4⁺CD25⁺ T regulatory (Treg) cells have been shown to inhibit adaptive responses by T cells. Natural killer (NK) cells represent an…”
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Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity by Sun, Kai, Wilkins, Danice E.C., Anver, Miriam R., Sayers, Thomas J., Panoskaltsis-Mortari, Angela, Blazar, Bruce R., Welniak, Lisbeth A., Murphy, William J.

“…We have recently demonstrated that the proteasome inhibitor, bortezomib, administered immediately following murine allogeneic bone marrow transplantation (BMT)…”
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CTL-Promoting Effects of CD40 Stimulation Outweigh B Cell-Stimulatory Effects Resulting in B Cell Elimination and Disease Improvement in a Murine Model of Lupus by Puliaev, Roman, Puliaeva, Irina, Welniak, Lisbeth A, Ryan, Abigail E, Haas, Mark, Murphy, William J, Via, Charles S

“…CD40/CD40L signaling promotes both B cell and CTL responses in vivo, the latter being beneficial in tumor models. Because CTL may also limit autoreactive B…”
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The role of growth hormone in T-cell development and reconstitution by Welniak, Lisbeth A., Sun, Rui, Murphy, William J.

“…Growth hormone (GH), directly or through GH‐induction of insulin‐like growth factor (IGF)‐1, has been implicated in lymphocyte development and function. Recent…”
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Immunomodulation and pharmacological strategies in the treatment of graft-versus-host disease by Li, Minghui, Sun, Kai, Welniak, Lisbeth A, Murphy, William J

“…Allogeneic hematopoietic stem cell transplantation offers great promise for the treatment of a variety of diseases including malignancies and other diseases of…”
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Expansion of LTC‐ICs and Maintenance of p21 and BCL‐2 Expression in Cord Blood CD34+/CD38− Early Progenitors Cultured over Human MSCs as a Feeder Layer by Kadereit, Suzanne, Deeds, Linda S., Haynesworth, Stephen E., Koc, Omer N., Kozik, Margaret M., Szekely, Emese, Daum‐Woods, Kathleen, Goetchius, Glenn W., Fu, Pingfu, Welniak, Lisbeth A., Murphy, William J., Laughlin, Mary J.

“…Allogeneic transplantation with umbilical cord blood (UCB) is limited in adult recipients by a low CD34+ cell dose. Clinical trials incorporating…”
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An absence of CCR5 on donor cells results in acceleration of acute graft-vs-host disease by Welniak, Lisbeth A, Wang, Zhao, Sun, Kai, Kuziel, William, Anver, Miriam R, Blazar, Bruce R, Murphy, William J

“…Chemokines have been postulated to play a role in the pathogenesis of graft-vs-host disease (GVHD) after allogeneic hematopoietic transplantation. Recent…”
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Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury by Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Rubin, Jeffrey S., Uren, Aykut, Welniak, Lisbeth A., Murphy, William J., Farrell, Catherine L., Lacey, David L., Blazar, Bruce R.

“…We have previously shown that pretreatment of mice with keratinocyte growth factor (KGF), an epithelial tissue repair factor, can ameliorate graft-versus-host…”
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IFN-γ mediates CD4 + T-cell loss and impairs secondary antitumor responses after successful initial immunotherapy by Murphy, William J, Berner, Vanessa, Liu, Haiyan, Zhou, Qing, Alderson, Kory L, Sun, Kai, Weiss, Jonathan M, Back, Timothy C, Longo, Dan L, Blazar, Bruce R, Wiltrout, Robert H, Welniak, Lisbeth A, Redelman, Doug

“…Protective cell-mediated immune responses in cancer are critically dependent on T-helper type 1 (T(H)1) cytokines such as interferon-gamma (IFN-gamma). We have…”
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Research opportunities in optimizing storage of red blood cell products by Wagner, Stephen J., Glynn, Simone A., Welniak, Lisbeth A.

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Neuroendocrine hormones such as growth hormone and prolactin are integral members of the immunological cytokine network by Redelman, Doug, Welniak, Lisbeth A., Taub, Dennis, Murphy, William J.

“…Neuroendocrine hormones such as growth hormone (GH) and prolactin (PRL) have been demonstrated to accelerate the recovery of the immune response after…”
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Differential effects of donor T-cell cytokines on outcome with continuous bortezomib administration after allogeneic bone marrow transplantation by Sun, Kai, Li, Minghui, Sayers, Thomas J., Welniak, Lisbeth A., Murphy, William J.

“…Dissociating graft-versus-tumor (GVT) effect from acute graft-versus-host disease (GVHD) still remains a great challenge in allogeneic bone marrow…”
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Strategies for More Rapid Translation of Cellular Therapies for Children: A US Perspective by SANCHEZ, Rosa, SILBERSTEIN, Leslie E, LINDBLAD, Robert W, WELNIAK, Lisbeth A, MONDORO, Traci Heath, WAGNER, John E

“…Clinical trials for pediatric diseases face many challenges, including trial design, accrual, ethical considerations for children as research subjects, and the…”
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IFN-γ receptor-deficient donor T cells mediate protection from graft-versus-host disease and preserve graft-versus-tumor responses after allogeneic bone marrow transplantation by Sun, Kai, Hsiao, Hui-Hua, Li, Minghui, Ames, Erik, Bouchlaka, Myriam, Welniak, Lisbeth A, Hagino, Takeshi, Jagdeo, Jared, Pai, Chien-Chun, Chen, Mingyi, Blazar, Bruce R, Abedi, Mehrdad, Murphy, William J

“…Graft-versus-host disease (GVHD) is a major complication of allogeneic bone marrow transplantation. It has been previously reported that lung GVHD severity…”
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Cell therapy product administration and safety: data capture and analysis from the Production Assistance for Cellular Therapies (PACT) program by Lindblad, Robert W., Ibenana, Laarni, Wagner, John E., McKenna Jr, David H., Hei, Derek J., Hematti, Peiman, Couture, Larry A., Silberstein, Leslie E., Armant, Myriam, Rooney, Cliona M., Gee, Adrian P., Welniak, Lisbeth A., Heath Mondoro, Traci, Wood, Deborah A., Styers, David

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