Search Results - "Wells, Tim"

A phenotypic screen of the Global Health Priority Box identifies an insecticide with anthelmintic activity by Shanley, Harrison T, Taki, Aya C, Byrne, Joseph J, Nguyen, Nghi, Wells, Tim N C, Jabbar, Abdul, Sleebs, Brad E, Gasser, Robin B

“…Infection with parasitic nematodes (helminths), particularly those of the order Strongylida (such as Haemonchus contortus), can cause significant and…”
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Structure activity relationship and target prediction for ABX464 analogues in Caenorhabditis elegans by Shanley, Harrison T, Taki, Aya C, Nguyen, Nghi, Wang, Tao, Byrne, Joseph J, Ang, Ching-Seng, Leeming, Michael G, Nie, Shuai, Williamson, Nicholas, Zheng, Yuanting, Young, Neil D, Korhonen, Pasi K, Hofmann, Andreas, Wells, Tim N C, Jabbar, Abdul, Sleebs, Brad E, Gasser, Robin B

“…Global challenges with treatment failures and/or widespread resistance in parasitic worms against commercially available anthelmintics lend impetus to the…”
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A High-Throughput Phenotypic Screen of the 'Pandemic Response Box' Identifies a Quinoline Derivative with Significant Anthelmintic Activity by Shanley, Harrison T, Taki, Aya C, Byrne, Joseph J, Jabbar, Abdul, Wells, Tim N C, Samby, Kirandeep, Boag, Peter R, Nguyen, Nghi, Sleebs, Brad E, Gasser, Robin B

“…Parasitic nematodes cause diseases in livestock animals and major economic losses to the agricultural industry worldwide. Nematodes of the order Strongylida,…”
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Structure-activity relationship and target investigation of 2-aryl quinolines with nematocidal activity by Shanley, Harrison T., Taki, Aya C., Nguyen, Nghi, Wang, Tao, Byrne, Joseph J., Ang, Ching-Seng, Leeming, Michael G., Nie, Shuai, Williamson, Nicholas, Zheng, Yuanting, Young, Neil D., Korhonen, Pasi K., Hofmann, Andreas, Chang, Bill C.H., Wells, Tim N.C., Häberli, Cécile, Keiser, Jennifer, Jabbar, Abdul, Sleebs, Brad E., Gasser, Robin B.

“…Within the context of our anthelmintic discovery program, we recently identified and evaluated a quinoline derivative, called ABX464 or obefazimod, as a…”
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Beyond the balloon: excimer coronary laser atherectomy used alone or in combination with rotational atherectomy in the treatment of chronic total occlusions, non-crossable and non-expansible coronary lesions by Fernandez, Juan P, Hobson, Alex R, McKenzie, Daniel, Shah, Nimit, Sinha, Manas K, Wells, Tim A, Levy, Terry M, Swallow, Rosie A, Talwar, Suneel, O'Kane, Peter D

“…To establish success and complication rates of excimer laser coronary atherectomy (ELCA) in a contemporary series of patients with balloon failure during…”
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Plasma Concentrations and Role of Macrophage Inflammatory Protein–1α during Chronic Schistosoma mansoni Infection in Humans by Falcão, Patrícia L., Correa-Oliveira, Rodrigo, Fraga, Lúcia A. O., Talvani, André, Proudfoot, Amanda E. I., Wells, Tim N. C., Williams, Timothy J., Jose, Peter J., Teixeira, Mauro M.

“…Chemokines play an important role during granulomatous inflammation in murine models of Schistosoma mansoni infection. Here, the expression and possible roles…”
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Donepezil overdose secondary to use of a smart home device for medication reminders by Sen, Gautam, Wells, Tim

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Tissue-Specific Transgenic Knockdown of Fos-Related Antigen 2 (Fra-2) Expression Mediated by Dominant Negative Fra-2 by Smith, Martin, Burke, Zoe, Humphries, Ann, Wells, Tim, Klein, David, Carter, David, Baler, Ruben

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Stem Cell Factor-Induced Leukotriene B4 Production Cooperates with Eotaxin to Mediate the Recruitment of Eosinophils During Allergic Pleurisy in Mice by Klein, Andre, Talvani, Andre, Silva, Patricia M. R, Martins, Marco A, Wells, Tim N. C, Proudfoot, Amanda, Luckacs, Nick W, Teixeira, Mauro M

“…The understanding of the mechanisms underlying eosinophil recruitment in vivo may aid in the development of novel strategies for the treatment of allergic…”
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Lateral Nodal Features on Restaging Magnetic Resonance Imaging Associated With Lateral Local Recurrence in Low Rectal Cancer After Neoadjuvant Chemoradiotherapy or Radiotherapy by Ogura, Atsushi, Konishi, Tsuyoshi, Beets, Geerard L, Cunningham, Chris, Garcia-Aguilar, Julio, Iversen, Henrik, Toda, Shigeo, Lee, In Kyu, Lee, Hong Xiang, Uehara, Keisuke, Lee, Peter, Putter, Hein, van de Velde, Cornelis J H, Rutten, Harm J T, Tuynman, Jurriaan B, Kusters, Miranda

“…Previously, it was shown in patients with low rectal cancer that a short-axis (SA) lateral node size of 7 mm or greater on primary magnetic resonance imaging…”
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TCT-293 A Deep Dive Into Rotational Atherectomy-Associated Coronary Perforation From 7 High-Volume European PCI Centers by Mailey, Jonathan, Hogg, Meadhbh, De Silva, Kalpa, Johnson, Tom, Strange, Julian, Deharo, Pierre, Biswas, Sinjini, Ladwiniec, Andrew, Wells, Tim, Mozid, Abdul, Kam Wa, Matthew Li, Abdulrahman, Balen, Dutta, Subhabrata, Veerasamy, Murugapathy, Walsh, Simon

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TCT-80 The Everolimus-Eluting Synergy Megatron Drug-Eluting Stent Platform for Aorto-Ostial and Proximal Coronary Disease: Early Outcomes From the European Synergy Megatron Implanters’ Registry by Kam Wa, Matthew Li, de Silva, Kalpa, Wells, Tim, Mozid, Abdul, Ladwiniec, Andrew, Hynes, Brian Gerard, Kotecha, Ash, Ratib, Karim, Biswas, Sinjini, Amabile, Nicolas, Deharo, Pierre, McEntegart, Margaret, Spratt, James, Digne, Franck, Hogg, Meadhbh, Mailey, Jonathan, Walsh, Simon, Kalra, Sundeep

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Exploring the key drivers of forest flammability in wet eucalypt forests using expert-derived conceptual models by Cawson, Jane G., Hemming, Victoria, Ackland, Andrew, Anderson, Wendy, Bowman, David, Bradstock, Ross, Brown, Tegan P., Burton, Jamie, Cary, Geoffrey J., Duff, Thomas J., Filkov, Alexander, Furlaud, James M., Gazzard, Tim, Kilinc, Musa, Nyman, Petter, Peacock, Ross, Ryan, Mike, Sharples, Jason, Sheridan, Gary, Tolhurst, Kevin, Wells, Tim, Zylstra, Phil, Penman, Trent D.

“…Context Fire behaviour research has largely focused on dry ecosystems that burn frequently, with far less attention on wetter forests. Yet, the impacts of fire…”
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Structure-activity relationships in engineered proteins: analysis of use of binding energy by linear free energy relationships by Fersht, Alan R, Leatherbarrow, Robin J, Wells, Tim N. C

“…The activity of mutant enzymes can be analyzed quantitatively by structure-activity relationships in a manner analogous to Brønsted or Hammett plots for simple…”
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The everolimus eluting Synergy Megatron TM drug-eluting stent platform: Early outcomes from the European Synergy Megatron TM Implanters' Registry by De Silva, Kalpa, Li Kam Wa, Matthew E, Wells, Tim, Mozid, Abdul, Ladwiniec, Andrew, Hynes, Brian G, Kotecha, Ashish, Ratib, Karim, Biswas, Sinjini, Amabile, Nicolas, Deharo, Pierre, McEntagart, Margaret, Spratt, James C, Digne, Franck, Hogg, Meadhbh, Mailey, Jonathan A, Walsh, Simon J, Kalra, Sundeep S

“…The Synergy Megatron is an everolimus-drug eluting stent that may offer advantages in the treatment of aorto-ostial disease and large proximal vessels. To…”
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The everolimus eluting Synergy MegatronTM drug‐eluting stent platform: Early outcomes from the European Synergy MegatronTM Implanters' Registry by De Silva, Kalpa, Li Kam Wa, Matthew E., Wells, Tim, Mozid, Abdul, Ladwiniec, Andrew, Hynes, Brian G., Kotecha, Ashish, Ratib, Karim, Biswas, Sinjini, Amabile, Nicolas, Deharo, Pierre, McEntagart, Margaret, Spratt, James C., Digne, Franck, Hogg, Meadhbh, Mailey, Jonathan A., Walsh, Simon J., Kalra, Sundeep S.

“…Background The Synergy MegatronTM is an everolimus‐drug eluting stent that may offer advantages in the treatment of aorto‐ostial disease and large proximal…”
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Guests in the Classroom: Top Ten Tips for Preservice Teachers by Ward, Martin J., Wells, Tim J.

“…Preservice teachers generally are confident and enthusiastic about their abilities to teach effectively. These desirable qualities are based, for the most…”
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Use of binding energy in catalysis analyzed by mutagenesis of the tyrosyl-tRNA synthetase by Wells, Tim N. C, Fersht, Alan R

“…The utilization of enzyme-substrate binding energy in catalysis has been investigated by experiments on mutant tyrosyl-tRNA synthetases that have been…”
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Quantitative analysis of structure-activity relationships in engineered proteins by linear free-energy relationships by Fersht, Alan R, Leatherbarrow, Robin J, Wells, Tim N. C

“…Protein engineering is being used increasingly to study the fine details of the structure and activity of enzymes. The activities of many mutant…”
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Orbital Varix Thrombosis and Review of Orbital Vascular Anomalies in Blue Rubber Bleb Nevus Syndrome by Shams, Pari N, Cugati, Sudha, Wells, Tim, Huilgol, Shyamala, Selva, Dinesh

“…A 57-year-old woman with cutaneous manifestations of (BRBNS) presented with acute left proptosis and venous congestion secondary to thrombosis within a…”
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