Search Results - "Wells, Keith"

Performance assessment of ISO-5167 and symmetrical Venturi meters for measuring low Reynolds number turbulent incompressible isothermal flow by Sharifian, Ahmad, Wells, Keith

“…The selection of Venturis depends on the desired flow measurement sensitivity, permanent pressure loss, discharge coefficient, and relative pressure loss…”
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Design of short Venturi flow meters for incompressible and isothermal flow applications by Wells, Keith, Sharifian, Ahmad

“…The Venturi flow meter offers a range of measurement options for liquids, gas, steam, and slurries in piped systems. The main criteria for assessing Venturi…”
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Targeting the WNT Signaling Pathway in Cancer Therapeutics by Tai, David, Wells, Keith, Arcaroli, John, Vanderbilt, Chad, Aisner, Dara L., Messersmith, Wells A., Lieu, Christopher H.

“…The WNT signaling cascade is integral in numerous biological processes including embryonic development, cell cycle regulation, inflammation, and cancer…”
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Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma by Hintzsche, Jennifer D, Gorden, Nicholas T, Amato, Carol M, Kim, Jihye, Wuensch, Kelsey E, Robinson, Steven E, Applegate, Allison J, Couts, Kasey L, Medina, Theresa M, Wells, Keith R, Wisell, Joshua A, McCarter, Martin D, Box, Neil F, Shellman, Yiqun G, Gonzalez, Rene C, Lewis, Karl D, Tentler, John J, Tan, Aik Choon, Robinson, William A

“…Mucosal melanomas are a rare subtype of melanoma, arising in mucosal tissues, which have a very poor prognosis due to the lack of effective targeted therapies…”
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Oxaliplatin-Induced Neuropathy in Colorectal Cancer by Weickhardt, Andrew, Messersmith, Wells, Wells, Keith

“…Oxaliplatin use in palliative and adjuvant treatment of colon cancer is frequently limited by cumulative neurotoxicity, leading to reduced quality of life and…”
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An automated fabrication strategy to create patterned tubular architectures at cell and tissue scales by Othman, Rebeen, E Morris, Gavin, Shah, Disheet A, Hall, Stephen, Hall, Graham, Wells, Keith, Shakesheff, Kevin M, Dixon, James E

“…The use of materials to impose tissue-like architecture at cell resolution will be important if engineered functional replacements for damaged cardiovascular,…”
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Clinical proof of principle for ChimeriVax™: recombinant live, attenuated vaccines against flavivirus infections by Monath, Thomas P, McCarthy, Karen, Bedford, Philip, Johnson, Casey T, Nichols, Richard, Yoksan, Sutee, Marchesani, Ron, Knauber, Michael, Wells, Keith H, Arroyo, Juan, Guirakhoo, Farshad

“…ChimeriVax™ is a live, attenuated recombinant virus constructed from yellow fever (YF) 17D in which the envelope protein genes of YF 17D are replaced with the…”
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Systematic Analysis of Whole Exome Sequencing Determines RET G691S Polymorphism as Germline Variant in Melanoma by Smith Jr, Brent J., Hintzsche, Jennifer D., Amato, Carol M., Tan, Aik-Choon, Wells, Keith R., Applegate, Allison J., Gonzalez, Rita T., Barr, Jodie R., Robinson, William A.

“…The RET proto-oncogene encodes a receptor tyrosine kinase that is activated by glial cell derived neutrotrophic factor (GDNF). Previous studies have found that…”
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Genomic profiling of melanomas of unknown primary by Wells, Keith Ryan, Hintzsche, Jennifer, Amato, Carol M, Robinson, William

“…Abstract only e21048 Background: Approximately 2-10% of metastatic melanoma patients present without an identifiable primary melanocytic lesion. These…”
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Identification of somatic mutations and neoantigens to predict development of autoimmune adverse events to immune therapy in melanoma by Wells, Keith Ryan, Amato, Carol M, Hintzsche, Jennifer, Robinson, William

“…Abstract only 19 Background: Immunotherapy has quickly altered the treatment paradigm for advanced melanoma. Prior studies using whole exome sequencing (WES)…”
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Identification of somatic mutations to predict development of autoimmune adverse events to immune therapy in melanoma by Wells, Keith Ryan, Amato, Carol M, Hintzsche, Jennifer, Robinson, William

“…Abstract only…”
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Abstract 5002: Investigating the role of NF- κB signaling and immune checkpoint blockade therapy in melanoma by Wells, Keith, Hintzsche, Jennifer, Amato, Carol M., Tobin, Richard, Vorwald, Victoria, McCarter, Martin, Shellman, Yiqun, Tan, Aik Choon, Robinson, William

“…Abstract Immune checkpoint blockade (ICB) treatments, such as anti-PD1, improves survival in patients with metastatic melanoma. Despite durable response rates,…”
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ALK Inhibitor Response in Melanomas Expressing EML4-ALK Fusions and Alternate ALK Isoforms by Couts, Kasey L, Bemis, Judson, Turner, Jacqueline A, Bagby, Stacey M, Murphy, Danielle, Christiansen, Jason, Hintzsche, Jennifer D, Le, Anh, Pitts, Todd M, Wells, Keith, Applegate, Allison, Amato, Carol, Multani, Pratik, Chow-Maneval, Edna, Tentler, John J, Shellman, Yiqun G, Rioth, Matthew J, Tan, Aik-Choon, Gonzalez, Rene, Medina, Theresa, Doebele, Robert C, Robinson, William A

“…Oncogenic fusions occur in several types of cancer and can be effectively treated with ALK inhibitors; however, fusions and treatment response have not been…”
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Kinase gene fusions in defined subsets of melanoma by Turner, Jacqueline, Couts, Kasey, Sheren, Jamie, Saichaemchan, Siriwimon, Ariyawutyakorn, Witthawat, Avolio, Izabela, Cabral, Ethan, Glogowska, Magdelena, Amato, Carol, Robinson, Steven, Hintzsche, Jennifer, Applegate, Allison, Seelenfreund, Eric, Gonzalez, Rita, Wells, Keith, Bagby, Stacey, Tentler, John, Tan, Aik‐Choon, Wisell, Joshua, Varella‐Garcia, Marileila, Robinson, William

“…Summary Genomic rearrangements resulting in activating kinase fusions have been increasingly described in a number of cancers including malignant melanoma, but…”
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Pre-Treatment Mutational and Transcriptomic Landscape of Responding Metastatic Melanoma Patients to Anti-PD1 Immunotherapy by Amato, Carol M, Hintzsche, Jennifer D, Wells, Keith, Applegate, Allison, Gorden, Nicholas T, Vorwald, Victoria M, Tobin, Richard P, Nassar, Kelsey, Shellman, Yiqun G, Kim, Jihye, Medina, Theresa M, Rioth, Matthew, Lewis, Karl D, McCarter, Martin D, Gonzalez, Rene, Tan, Aik-Choon, Robinson, William A

“…Immunotherapy, such as anti-PD1, has improved the survival of patients with metastatic melanoma. However, predicting which patients will respond to…”
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Comprehensive genomic profiling of acral and mucosal melanomas to support clinical decision making by Classon, Anthony, Couts, Kasey, Gay, Laurie M., Yilmazel, Bahar, Patriquin, Caitlin, Applegate, Allison, Wells, Keith Ryan, Turner, Jacqueline, Ali, Siraj Mahamed, Benson, Adam, Miller, Vincent A., Ross, Jeffrey S., Mughal, Tariq I., Robinson, William

“…Abstract only…”
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Gender differences in melanoma prognostic factors by Farahi, Jessica M, Fazzari, Melissa, Braunberger, Taylor, Caravaglio, Joseph V, Kretowicz, Alexandra, Wells, Keith, Dellavalle, Robert P, Norris, David, Alkousakis, Theodore

“…Although previous studies identify gender differences in melanoma, limited research on the phenomenon exists. In this retrospective chart review, 1,156 adults…”
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Greater distance to an academic medical center is associated with poorer melanoma prognostic factors: The University of Colorado Experience by Snyder, Blake M, Mounessa, Jessica S, Fazzari, Melissa, Caravaglio, Joseph V, Kretowicz, Alexandra, Braunberger, Taylor, Wells, Keith, Dunnick, Cory A, Dellavalle, Robert P, Alkousakis, Theodore

“…Numerous studies report a correlation between distance to diagnostic provider in an academic medical center and poorer prognosis ofdisease. Limited research on…”
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Advocating the ecocentric paradigm in nursing by Wells, Keith

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The Nature of Morality and Its Implications for Chiropractic Educators in Ethics by Wells, Keith A.

“…It is well known that chiropractic colleges teach ethics and professional responsibility to chiropractic students. Casual observation shows faculty members and…”
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