Search Results - "Wells, Graham M.A"

Stromelysin-1 (matrix metalloproteinase-3) and tissue inhibitor of metalloproteinase-3 are overexpressed in the wall of abdominal aortic aneurysms by CARRELL, Tom W. G, BURNAND, Kevin G, WELLS, Graham M. A, CLEMENTS, John M, SMITH, Alberto

“…Atherosclerosis is implicated in the pathogenesis of abdominal aortic aneurysm (AAA) but more often causes aortic occlusive disease (AOD). The matrix…”
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Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor- α inhibitor by Clements, John M, Cossins, Judy A, Wells, Graham M.A, Corkill, Dominic J, Helfrich, Karen, Wood, L.Mike, Pigott, Rod, Stabler, Gary, Ward, George A, Gearing, Andrew J.H, Miller, Karen M

“…Matrix metalloproteinases (MMPs) are a large family of Zn 2+ endopeptidases that are expressed in inflammatory conditions and are capable of degrading…”
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TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis by Clanchy, Felix I.L., Borghese, Federica, Bystrom, Jonas, Balog, Attila, Penn, Henry, Hull, Dobrina N., Wells, Graham M.A., Kiriakidis, Serafim, Taylor, Peter C., Sacre, Sandra M., Williams, Lynn M., Stone, Trevor W., Mageed, Rizgar A., Williams, Richard O.

“…The role of the innate immune system has been established in the initiation and perpetuation of inflammatory disease, but less attention has been paid to its…”
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Drug targeting to monocytes and macrophages using esterase-sensitive chemical motifs by Needham, Lindsey A, Davidson, Alan H, Bawden, Lindsay J, Belfield, Andrew, Bone, Elisabeth A, Brotherton, Deborah H, Bryant, Sam, Charlton, Michael H, Clark, Vanessa L, Davies, Stephen J, Donald, Alastair, Day, Francesca A, Krige, David, Legris, Valérie, McDermott, Joanne, McGovern, Yvonne, Owen, Jo, Patel, Sanjay R, Pintat, Stéphane, Testar, Richard J, Wells, Graham M A, Moffat, David, Drummond, Alan H

“…The therapeutic and toxic effects of drugs are often generated through effects on distinct cell types in the body. Selective delivery of drugs to specific…”
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Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis by KIESEIER, B. C, KIEFER, R, CLEMENTS, J. M, MILLER, K, WELLS, G. M. A, SCHWEITZER, T, GEARING, A. J. H, HARTUNG, H.-P

“…Matrix metalloproteinases (MMPs) comprise a group of proteolytic enzymes that are implicated in the pathogenesis of inflammatory diseases of the nervous system…”
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Quantitation of matrix metalloproteinases in cultured rat astrocytes using the polymerase chain reaction with a multi-competitor cDNA standard by Wells, Graham M.A., Catlin, Graham, Cossins, Judy A., Mangan, Matthew, Ward, George A., Miller, Karen M., Clements, John M.

“…Matrix metalloproteinases (MMPs) are a family of Zn2+ endopeptidases that are expressed in many inflammatory conditions and that contribute to connective…”
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