Search Results - "Wells, Andy"
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Screening of organic solvents for bioprocesses using aqueous-organic two-phase systems
Published in Biotechnology advances (15-11-2018)“…The application of conventional organic solvents has been essential in several steps of bioprocesses in order to achieve sufficient economic efficiency. The…”
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Biocatalysis as a Strategic Green Technology for the Chemical Industry
Published in ChemCatChem (01-04-2014)“…Green thumbs…︁up? We look at the current state‐of‐the‐art use of biocatalysis and biotechnology to deliver more sustainable manufacturing across a range of…”
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Oxidation and Oxidative Reactions
Published in Organic process research & development (20-11-2015)Get full text
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Continuous Flow Hydrogenation of a Pharmaceutical Intermediate, [4-(3,4-Dichlorophenyl)-3,4-dihydro-2H-naphthalenyidene]methylamine, in Supercritical Carbon Dioxide
Published in Advanced synthesis & catalysis (10-12-2007)“…The hydrogenation of complex pharmaceutical intermediate, rac‐sertraline imine has been optimized as a continuous flow process utilizing a palladium/calcium…”
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The Enzyme Spring: Biocatalysis at its Best
Published in ChemCatChem (01-04-2014)“…Enzymes of the (R)evolution: This Special Issue on biocatalysis is packed full of new developments and applications in enzymatic catalysis, with contributions…”
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A Practical and Robust Process to Produce SB-214857, Lotrafiban, ((2 S )-7-(4,4 ‘ -Bipiperidinylcarbonyl)-2,3,4,5-tetrahydro-4-methyl-3-oxo-1 H -1, 4-Benzodiazepine-2-acetic Acid) Utilising an Enzymic Resolution as the Final Step
Published in Organic process research & development (01-07-2002)Get full text
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A Practical and Robust Process to Produce SB-214857, Lotrafiban, ((2S)-7-(4,4‘-Bipiperidinylcarbonyl)-2,3,4,5-tetrahydro-4-methyl-3-oxo-1H-1, 4-Benzodiazepine-2-acetic Acid) Utilising an Enzymic Resolution as the Final Step
Published in Organic process research & development (19-07-2002)“…During the scale-up of a chemical process to produce phase II supplies of the chiral compound Lotrafiban, partial racemisation occurred to produce drug…”
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Polymer-Supported Catalase: A Green Approach to the Removal of Hydrogen Peroxide from Reaction Mixtures
Published in Organic process research & development (01-07-2002)“…During a programme of work directed at developing a manufacturing route for SB 214857, Lotrafiban, the need arose to find methodology for efficiently…”
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Training and Environmental Management Systems
Published in ISO 14001 and Beyond (1997)“…Environmental management training has been found to be an area of deficiency in commercial training provision. Levels of commitment throughout the organisation…”
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Book Chapter -
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Hummingbird folding bike
Published in Director (London, England : 1983) (01-09-2017)“…The slim wheels and frame absorb bumps well and, once you get the hang of it, the folding process is simple. The only real catches are its size - the…”
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