Search Results - "Wells, Amber"

A transgenic mouse for in vivo detection of endogenous labeled mRNA by Singer, Robert H, Lionnet, Timothée, Czaplinski, Kevin, Darzacq, Xavier, Shav-Tal, Yaron, Wells, Amber L, Chao, Jeffrey A, Park, Hye Yoon, de Turris, Valeria, Lopez-Jones, Melissa

“…Tagging the endogenous beta-actin locus with an MS2-binding cassette allows live-cell imaging of mRNA in real time. Live-cell single mRNA imaging is a powerful…”
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β-Actin mRNA compartmentalization enhances focal adhesion stability and directs cell migration by Katz, Zachary B, Wells, Amber L, Park, Hye Yoon, Wu, Bin, Shenoy, Shailesh M, Singer, Robert H

“…Directed cell motility is at the basis of biological phenomena such as development, wound healing, and metastasis. It has been shown that substrate attachments…”
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The structure of the myosin VI motor reveals the mechanism of directionality reversal by Houdusse, Anne, Ménétrey, Julie, Bahloul, Amel, Wells, Amber L, Yengo, Christopher M, Morris, Carl A, Sweeney, H. Lee

“…Here we solve a 2.4-A structure of a truncated version of the reverse-direction myosin motor, myosin VI, that contains the motor domain and binding sites for…”
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Regulation of local expression of cell adhesion and motility-related mRNAs in breast cancer cells by IMP1/ZBP1 by Gu, Wei, Katz, Zachary, Wu, Bin, Park, Hye Yoon, Li, Deling, Lin, Stanley, Wells, Amber L, Singer, Robert H

“…Metastasis involves tumor cell detachment from the primary tumor, and acquisition of migratory and invasive capabilities. These capabilities are mediated by…”
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An Unbiased Analysis Method to Quantify mRNA Localization Reveals Its Correlation with Cell Motility by Park, Hye Yoon, Trcek, Tatjana, Wells, Amber L., Chao, Jeffrey A., Singer, Robert H.

“…Localization of mRNA is a critical mechanism used by a large fraction of transcripts to restrict its translation to specific cellular regions. Although current…”
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Examining the role of MEDLINE as a patient care information resource: an analysis of data from the Value of Libraries study by Dunn, Kathel, Marshall, Joanne Gard, Wells, Amber L, Backus, Joyce E B

“…This study analyzed data from a study on the value of libraries to understand the specific role that the MEDLINE database plays in relation to other…”
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Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors by WEIGANG WANG, GOSWAMI, Sumanta, LAPIDUS, Kyle, WELLS, Amber L, WYCKOFF, Jeffrey B, SAHAI, Erik, SINGER, Robert H, SEGALL, Jeffrey E, CONDEELIS, John S

“…We subjected cells collected using an in vivo invasion assay to cDNA microarray analysis to identify the gene expression profile of invasive carcinoma cells in…”
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Feedback Regulation between Zipcode Binding Protein 1 and β-Catenin mRNAs in Breast Cancer Cells by Gu, Wei, Wells, Amber L., Pan, Feng, Singer, Robert H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A structural state of the myosin V motor without bound nucleotide by Sweeney, H. Lee, Houdusse, Anne, Coureux, Pierre-Damien, Wells, Amber L, Ménétrey, Julie, Yengo, Christopher M, Morris, Carl A

“…The myosin superfamily of molecular motors use ATP hydrolysis and actin-activated product release to produce directed movement and force. Although this is…”
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Myosin VI is a Processive Motor with a Large Step Size by Rock, Ronald S., Rice, Sarah E., Wells, Amber L., Purcell, Thomas J., Spudich, James A., Sweeney, H. Lee

“…Myosin VI is a molecular motor involved in intracellular vesicle and organelle transport. To carry out its cellular functions myosin VI moves toward the…”
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The Kinetic Mechanism of Myosin V by De La Cruz, Enrique M., Wells, Amber L., Rosenfeld, Steven S., Ostap, E. Michael, Sweeney, H. Lee

“…Myosin V is an unconventional myosin proposed to be processive on actin filaments, analogous to kinesin on a microtubule [Mehta, A. D., et al. (1999) Nature…”
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The Value of Library and Information Services in Nursing and Patient Care by Marshall, Joanne, Morgan, Jennifer, Klem, Mary, Thompson, Cheryl, Wells, Amber

“…Libraries are a primary resource for evidence-based practice. This study, using a critical incident survey administered to 6,788 nurses at 118 hospitals,…”
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Library and information services: impact on patient care quality by Marshall, Joanne Gard, Morgan, Jennifer Craft, Thompson, Cheryl A, Wells, Amber L

“…The purpose of this paper is to explore library and information service impact on patient care quality. A large-scale critical incident survey of physicians…”
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Myosin VI is an actin-based motor that moves backwards by Sweeney, H. Lee, Wells, Amber L, Lin, Abel W, Chen, Li-Qiong, Safer, Daniel, Cain, Shane M, Hasson, Tama, Carragher, Bridget O, Milligan, Ronald A

“…Myosins and kinesins are molecular motors that hydrolyse ATP to track along actin filaments and microtubules, respectively. Although the kinesin family…”
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Biochemical and Structural Characterization of the Gem GTPase by Splingard, Anne, Ménétrey, Julie, Perderiset, Mylène, Cicolari, Jérome, Regazzoni, Karine, Hamoudi, Fatima, Cabanié, Lucien, El Marjou, Ahmed, Wells, Amber, Houdusse, Anne, de Gunzburg, Jean

“…RGK proteins, encompassing Rad, Gem, Rem1, and Rem2, constitute an intriguing branch of the Ras superfamily; their expression is regulated at the transcription…”
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The Unique Insert in Myosin VI Is a Structural Calcium-Calmodulin Binding Site by Bahloul, Amel, Chevreux, Guillaume, Wells, Amber L., Martin, Davy, Nolt, Jocelyn, Yang, Zhaohui, Chen, Li-Qiong, Potier, Noëlle, Van Dorsselaer, Alain, Rosenfeld, Steve, Houdusse, Anne, Sweeney, H. Lee, Spudich, James A.

“…Myosin VI contains an inserted sequence that is unique among myosin superfamily members and has been suggested to be a determinant of the reverse…”
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Actin and Light Chain Isoform Dependence of Myosin V Kinetics by De La Cruz, Enrique M, Wells, Amber L, Sweeney, H. Lee, Ostap, E. Michael

“…Recent studies on myosin V report a number of kinetic differences that may be attributed to the different heavy chain (chicken vs mouse) and light chain…”
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Calcium Functionally Uncouples the Heads of Myosin VI by Morris, Carl A, Wells, Amber L, Yang, Zhaohui, Chen, Li-Qiong, Baldacchino, Corradina V, Sweeney, H Lee

“…This study examines the steady state activity and in vitro motility of single-headed (S1) and double-headed (HMM) myosin VI constructs within the context of…”
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An actin-dependent conformational change in myosin by Sweeney, H. Lee, Selvin, Paul R, Xiao, Ming, Reifenberger, Jeff G, Wells, Amber L, Baldacchino, Corry, Chen, Li-Qiong, Ge, Pinghua

“…Conformational changes within myosin lead to its movement relative to an actin filament. Several crystal structures exist for myosin bound to various…”
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Kinetic and Spectroscopic Evidence for Three Actomyosin:ADP States in Smooth Muscle by Rosenfeld, Steven S., Xing, Jun, Whitaker, Michael, Cheung, Herbert C., Brown, Fred, Wells, Amber, Milligan, Ron A., Sweeney, H. Lee

“…Smooth muscle myosin II undergoes an additional movement of the regulatory domain with ADP release that is not seen with fast skeletal muscle myosin II. In…”
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