Search Results - "Wellington, Andrea"
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Impaired dopamine signaling in early diabetic retina: Insights from D1R and D4R agonist effects on whole retina responses
Published in Experimental eye research (01-10-2024)“…The retina has low dopamine levels early in diabetes. To determine how low dopamine levels affected dopamine signaling, the effects of dopamine receptor…”
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Impaired Light Adaptation of ON-Sustained Ganglion Cells in Early Diabetes Is Attributable to Diminished Response to Dopamine D4 Receptor Activation
Published in Investigative ophthalmology & visual science (25-01-2022)“…Retinal neuronal signaling is disrupted early in diabetes, before the onset of the vascular pathologies associated with diabetic retinopathy. There is also…”
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Miro's N-terminal GTPase domain is required for transport of mitochondria into axons and dendrites
Published in The Journal of neuroscience (08-04-2015)“…Mitochondria are dynamically transported in and out of neuronal processes to maintain neuronal excitability and synaptic function. In higher eukaryotes, the…”
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Early diabetes impairs ON sustained ganglion cell light responses and adaptation without cell death or dopamine insensitivity
Published in Experimental eye research (01-11-2020)“…Retinal signaling under dark-adapted conditions is perturbed during early diabetes. Additionally, dopamine, the main neuromodulator of retinal light…”
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The GTPase dMiro Is Required for Axonal Transport of Mitochondria to Drosophila Synapses
Published in Neuron (Cambridge, Mass.) (04-08-2005)“…We have identified EMS-induced mutations in Drosophila Miro (dMiro), an atypical mitochondrial GTPase that is orthologous to human Miro (hMiro). Mutant dmiro…”
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Drosophila Miro Is Required for Both Anterograde and Retrograde Axonal Mitochondrial Transport
Published in The Journal of neuroscience (29-04-2009)“…Microtubule-based transport of mitochondria into dendrites and axons is vital for sustaining neuronal function. Transport along microtubule tracks proceeds in…”
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Effects of imaging conditions on mitochondrial transport and length in larval motor axons of Drosophila
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-10-2008)“…The distribution of mitochondria is sensitive to physiological stresses and changes in metabolic demands. Consequently, it is important to carefully define the…”
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Spire contains actin binding domains and is related to ascidian posterior end mark-5
Published in Development (Cambridge) (01-12-1999)“…Spire is a maternal effect locus that affects both the dorsal-ventral and anterior-posterior axes of the Drosophila egg and embryo. It is required for…”
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A field study of success and failure factors in asynchronous groupware supported process improvement groups
Published in Business process management journal (01-09-1999)“…Process-focused improvement groups form the change dynamic in two world-class paradigms of change management - TQM and BPR. This paper outlines a research…”
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