Search Results - "Wellinger, Ralf Erik"
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Role for RNA:DNA hybrids in origin-independent replication priming in a eukaryotic system
Published in Proceedings of the National Academy of Sciences - PNAS (05-05-2015)“…Significance R-loop formation has been related to genome instability and human disease, yet the role of R-loops in replication priming remains to be explored…”
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Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases
Published in International journal of molecular sciences (11-12-2022)“…Understanding which intracellular signaling pathways are activated by manganese stress is crucial to decipher how metal overload compromise cellular integrity…”
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3
Using yeast to model calcium-related diseases: Example of the Hailey–Hailey disease
Published in Biochimica et biophysica acta (01-10-2014)“…Cross-complementation studies offer the possibility to overcome limitations imposed by the inherent complexity of multicellular organisms in the study of human…”
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4
Mind the nick
Published in Cell cycle (Georgetown, Tex.) (02-01-2019)“…Genomic DNA can be prone to endogenous nicks. The contribution of DNA nicks to genome instability includes the breakage of double-stranded DNA due to…”
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Impaired Manganese Metabolism Causes Mitotic Misregulation
Published in The Journal of biological chemistry (25-05-2012)“…Manganese is an essential trace element, whose intracellular levels need to be carefully regulated. Mn2+ acts as a cofactor for many enzymes and excess of Mn2+…”
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Phytoplasma DNA Enrichment from Sugarcane White Leaves for Shotgun Sequencing Improvement
Published in Plants (Basel) (01-11-2024)“…Sugarcane white leaf (SCWL) disease, caused by Candidatus Phytoplasma sacchari, poses a significant threat to sugarcane cultivation. An obligate parasite,…”
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Manganese is a physiologically relevant TORC1 activator in yeast and mammals
Published in eLife (29-07-2022)“…The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human diseases. Whether intracellular Mn…”
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The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection
Published in International journal of molecular sciences (03-01-2021)“…Golgi trafficking depends on the small GTPase Arf1 which, upon activation, drives the assembly of different coats onto budding vesicles. Two related types of…”
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Surface modulation of single-walled carbon nanotubes for selective bacterial cell agglutination
Published in International journal of nanomedicine (01-05-2019)“…Bacterial resistance to antibiotics is one of the biggest challenges facing medicine today. Anti-adhesive therapy, using inhibitors of bacterial adhesion to…”
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Adaptive Response of Saccharomyces Hosts to Totiviridae L-A dsRNA Viruses Is Achieved through Intrinsically Balanced Action of Targeted Transcription Factors
Published in Journal of fungi (Basel) (09-04-2022)“…L-A virus is a widespread yeast dsRNA virus. The persistence of the L-A virus alone appears to be symptomless, but the concomitant presence of a satellite M…”
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Yeast as a model system to study metabolic impact of selenium compounds
Published in Microbial cell (08-04-2015)“…Inorganic Se forms such as selenate or selenite (the two more abundant forms in nature) can be toxic in cells, which constitute an adequate model to study such…”
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DNA repair in a yeast origin of replication: contributions of photolyase and nucleotide excision repair
Published in Nucleic acids research (15-05-2000)“…DNA damage formation and repair are tightly linked to protein-DNA interactions in chromatin. We have used minichromosomes in yeast as chromatin substrates in…”
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Zim17/Tim15 links mitochondrial iron-sulfur cluster biosynthesis to nuclear genome stability
Published in Nucleic acids research (01-08-2011)“…Genomic instability is related to a wide-range of human diseases. Here, we show that mitochondrial iron-sulfur cluster biosynthesis is important for the…”
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Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene
Published in The EMBO journal (15-08-1997)“…Nucleotide excision repair (NER) is a major pathway to remove pyrimidine dimers (PDs), a class of DNA lesions generated by ultraviolet light. Since folding of…”
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Architecture of the Replication Fork Stalled at the 3′ End of Yeast Ribosomal Genes
Published in Molecular and Cellular Biology (01-08-2000)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Rad52-Independent Accumulation of Joint Circular Minichromosomes during S Phase in Saccharomyces cerevisiae
Published in Molecular and Cellular Biology (01-09-2003)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Taq DNA Polymerase Blockage at Pyrimidine Dimers
Published in Nucleic acids research (15-04-1996)“…The most stable DNA-lesions generated by irradiation with ultraviolet light (254 nm) are two kinds of pyrimidine dimers (PDs), cylobutane pyrimidine dimers…”
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Non-Canonical Replication Initiation: You're Fired
Published in Genes (27-01-2017)“…The division of prokaryotic and eukaryotic cells produces two cells that inherit a perfect copy of the genetic material originally derived from the mother…”
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Manganese Redistribution by Calcium-stimulated Vesicle Trafficking Bypasses the Need for P-type ATPase Function
Published in The Journal of biological chemistry (10-04-2015)“…Regulation of intracellular ion homeostasis is essential for eukaryotic cell physiology. An example is provided by loss of ATP2C1 function, which leads to skin…”
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Methods to study transcription-coupled repair in chromatin
Published in Methods in molecular biology (Clifton, N.J.) (2009)“…Transcription-coupled repair (TCR) is a sub-pathway of nucleotide excision repair that allows for the enhanced repair of the transcribed strand of active…”
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