Search Results - "Welling, C M"

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia by Bernal-Mizrachi, E, Wen, W, Stahlhut, S, Welling, C M, Permutt, M A

“…The phosphoinositide 3-kinase-Akt/PKB pathway mediates the mitogenic effects various nutrients and growth factors in cultured cells. To study its effects in…”
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Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians by Inoue, H., Ferrer, J., Welling, C. M., Elbein, S. C., Hoffman, M., Mayorga, R., Warren-Perry, M., Zhang, Y., Millns, H., Turner, R., Province, M., Bryan, J., Permutt, M. A., Aguilar-Bryan, L.

“…Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians. H Inoue , J Ferrer , C M Welling , S C Elbein , M Hoffman ,…”
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Isolation and characterization of the human AKT1 gene, identification of 13 single nucleotide polymorphisms (SNPs) and their lack of association with Type II diabetes by MATSUBARA, A, WASSON, J. C, DONELAN, S. S, WELLING, C. M, GLASER, B, PERMUTT, M. A

“…AKT1, a serine/threonine protein kinase, is an important downstream target of the insulin-signalling pathway, with both anti-apoptotic and peripheral metabolic…”
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Human Cholecystokinin Type A Receptor Gene: Cytogenetic Localization, Physical Mapping, and Identification of Two Missense Variants in Patients with Obesity and Non-Insulin-Dependent Diabetes Mellitus (NIDDM) by Inoue, Hiroshi, Iannotti, Christopher A., Welling, Cris M., Veile, Rosalie, Donis-Keller, Helen, Permutt, M.Alan

“…The human CCKAR gene was previously mapped to chromosome 4 using a panel of human/hamster somatic cell hybrids. We now report the cytogenetic and physical…”
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Human Liver Glucokinase Gene: Cloning and Sequence Determination of Two Alternatively Spliced cDNAs by Tanizawa, Yukio, Koranyi, Laszlo I., Welling, Cris M., Permutt, M. Alan

“…A human liver glucokinase (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1) cDNA was isolated from a liver cDNA library. This cDNA (hLGLK1) appeared to be full…”
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Human islet glucokinase gene : isolation and sequence analysis of full-length cDNA by KORANYI, L. I, TANIZAWA, Y, WELLING, C. M, RABIN, D. U, PERMUTT, A. A

“…Pancreatic islet glucokinase (ATP:D-hexose-6-phosphotransferase) cDNAs were isolated from a human islet cDNA library in lambda-gt11. One clone (hlGLK2), 2723…”
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Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians by INOUE, H, FERRER, J, PROVINCE, M, BRYAN, J, PERMUTT, M. A, AGUILAR-BRYAN, L, WELLING, C. M, ELBEIN, S. C, HOFFMAN, M, MAYORGA, R, WARREN-PERRY, M, ZHANG, Y, MILLNS, H, TURNER, R

“…NIDDM is a common heterogeneous disorder, the genetic basis of which has yet to be determined. The sulfonylurea receptor (SUR) gene, now known to encode an…”
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Human islet glucokinase gene. Isolation and sequence analysis of full-length cDNA by Koranyi, L. I., Tanizawa, Y., Welling, C. M., Rabin, D. U., Permutt, M. A.

“…Human islet glucokinase gene. Isolation and sequence analysis of full-length cDNA. L I Koranyi , Y Tanizawa , C M Welling , D U Rabin and M A Permutt…”
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The Effect of Velocity on the Corrosion of Steel in Sulfuric Acid by Whitman, W. G, Russell, R. P, Welling, C. M, Cochrane, J. D

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The biological activity of single-stranded phi X174 DNA, modified by N-hydroxy-2-aminofluorene, is inhibited by guanine imidazole ring-opening of the major, non-lethal aminofluorene-DNA adduct by Lutgerink, J T, Retèl, J, Westra, J G, Welling, M C, Loman, H, Kriek, E

“…The major aminofluorene-DNA derivative, found in the liver of rats after administration of the hepatocarcinogen N-acetyl-2-aminofluorene and identified as…”
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Binding efficiency of antibodies to DNA modified with aromatic amines and polycyclic aromatic hydrocarbons: implications for quantification of carcinogen-DNA adducts in vivo by Kriek, E, Van Schooten, F J, Hillebrand, M J, Welling, M C

“…Antibodies raised against the bovine serum albumin conjugates of N-(guanosin-8-yl)-N-2-acetylaminofluorene (Guo-8-AAF), the imidazole ring-opened form of…”
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A bug in the brain and the future of neurosciences by Figueiredo, Eberval Gadelha, MD, PhD, Welling, Leonardo C., MD, PhD, Welling, Mariana S., MD, Teixeira, Manoel J., MD, PhD

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By-pass of the major aminofluorene-DNA adduct during in vivo replication of single- and double-stranded phi X174 DNA treated with N-hydroxy-2-aminofluorene by Lutgerink, J T, Retèl, J, Westra, J G, Welling, M C, Loman, H, Kriek, E

“…To examine the effects of aminofluorene-DNA adduct formation on the biological activity of DNA, single-stranded (ss) phi X174 DNA and phi X174 replicative form…”
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