Search Results - "Welham, K J"

Optimization of pH as a strategy to improve enzymatic saccharification of wheat straw for enhancing bioethanol production by Abdulsattar, M. O., Abdulsattar, J. O., Greenway, G. M., Welham, K. J., Zein, S. H.

“…In this work, wheat straw (WS) was used as a lignocellulosic substrate to investigate the influence of pH on enzymatic saccharification. The optimum enzymatic…”
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Identification of cytochrome P450 enzymes in human colorectal metastases and the surrounding liver: a proteomic approach by Lane, C.S., Nisar, S., Griffiths, W.J., Fuller, B.J., Davidson, B.R., Hewes, J., Welham, K.J., Patterson, L.H.

“…We describe the direct identification of multiple cytochrome P450 (CYP) enzymes in healthy and cancerous tissue. CYPs in human liver colorectal metastases were…”
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A PROTEOMIC APPROACH TO THE IDENTIFICATION OF CYTOCHROME P450 ISOFORMS IN MALE AND FEMALE RAT LIVER BY NANOSCALE LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION-TANDEM MASS SPECTROMETRY by NISAR, S, LANE, C. S, WILDERSPIN, A. F, WELHAM, K. J, GRIFFITHS, W. J, PATTERSON, L. H

“…Nanoscale reversed-phase liquid chromatography (LC) combined with electrospray ionization-tandem mass spectrometry (ESI-MS/MS) has been used as a method for…”
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A Preclinical Pharmacokinetic Study of the Bioreductive Drug AQ4N by LOADMAN, P. M, SWAINE, D. J, BIBBY, M. C, WELHAM, K. J, PATTERSON, L. H

“…AQ4N (1,4-bis-{[2-(dimethylamino- N -oxide)ethyl]amino}5,8-dihydroxyanthracene-9,10-dione) is in a class of bioreductive agents incorporating the aliphatic N…”
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Characterization of fungal spores by laser desorption/ionization time-of-flight mass spectrometry by Welham, K. J., Domin, M. A., Johnson, K., Jones, L., Ashton, D. S.

“…A considerable volume of research has now been completed on the application of matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) to the…”
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The characterization of micro-organisms by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Welham, Kevin J., Domin, Mark A., Scannell, D. Eoin, Cohen, E., Ashton, David S.

“…A variety of gram‐positive and gram‐negative intact bacterial cells have been analysed by matrix‐assisted laser desorption/ionization mass spectrometry…”
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Some electrospray mass spectrometric evidence for the existence of covalent O-acyl enzyme intermediates by Ashton, David S., Beddell, Christopher R., Cooper, David J., Green, Brian N., Oliver, Ronald W.A., Welham, Kevin J.

“…Electrospray mass spectrometry has been used to measure the masses of the species present in solutions of three serine proteases (α-chymotrypsin, subtilisin…”
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Identification of an endogenous inhibitor of AMP-activated protein kinase by Toomey, C M, Welham, K J, Munday, M R

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The effect of solvent and matrix combinations on the analysis of bacteria by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry by Domin, Mark A., Welham, Kevin J., Ashton, David S.

“…The ability to rapidly identify the taxonomic class of the wide variety of microorganisms involved in human and animal disease is becoming increasingly…”
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High-performance liquid chromatographic-mass spectrometric assay of high-value compounds for pharmaceutical use from plant cell tissue culture: Cinchona alkaloids by Abdulrahman, S, Harrison, M E, Welham, K J, Baldwin, M A, Phillipson, J D, Roberts, M F

“…The use of high-performance liquid chromatography (HPLC) interfaced with thermospray (TSP) mass spectrometry is described for the separation and identification…”
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Detection of nitric oxide in tissue samples by ESI-MS by Shen, Zheng, Webster, Abigail, Welham, Kevin J, Dyer, Charlotte E, Greenman, John, Haswell, Stephen J

“…A novel method to determine nitric oxide (NO) in biological tissue samples with minimal interference from the cellular detritus is described…”
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On the purity of 3X-recrystallized bovine alpha-chymotrypsin by Ashton, D S, Beddell, C R, Cooper, D J, Green, B N, Oliver, R W, Welham, K J

“…The results of an electrospray-mass spectrometric analytical study of aqueous solutions of fifteen commercial samples of 3X-recrystallized bovine…”
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Efficient protein digestion with peptide separation in a micro-device interfaced to electrospray mass spectrometry by Al-Lawati, Haider, Watts, Paul, Welham, Kevin J

“…A highly efficient protein digestion device has been fabricated using commercially available immobilized trypsin on agarose beads, packed into a silica…”
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Quantitative analysis of the major constituents of St John's wort with HPLC-ESI-MS by Chandrasekera, Dhammitha H., Heinrich, Michael, Ashton, David, Welham, Kevin J., Middleton, Richard

“…A method was developed to profile the major constituents of St John's wort extracts using highperformance liquid chromatography‐electrospray mass spectrometry…”
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Identification of proteins associated with radiotherapy resistance in breast cancer cells: a combined proteomic and microarray screening approach by Smith, L, Qutob, O, Watson, MB, Beavis, AW, Jameel, JKA, Welham, KJ, Drew, PJ, Lind, MJ, Cawkwell, L

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Conjugated linoleic acid isomers and trans fatty acids inhibit fatty acid transport in hepatoma 7288CTC and inguinal fat pads in Buffalo rats by Sauer, Leonard A, Dauchy, Robert T, Blask, David E, Krause, Jean A, Davidson, Leslie K, Dauchy, Erin M, Welham, Kevin J, Coupland, Keith

“…Conjugated linoleic acid (CLA) and some trans fatty acids (FA) decrease tumor growth and alter tumor and host lipid uptake and storage. The goal of this study…”
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Matrix-assisted Laser-desorption/Ionization Time-of-flight Mass Spectrometry and its Application to the Analysis of Fungal Spores by WELHAM, K. J., DOMIN, M. A., JOHNSON, K., JONES, L., ASHTON, D. S.

“…Although much research has been completed on the application of matrix‐assisted laser‐desorption/ionization mass spectrometry (MALDI‐MS) to the analysis of…”
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Two-dimensional high-performance liquid chromatographic method for assaying S-adenosyl-L-methionine and its related metabolites in tissues by Hamedani, M P, Valkó, K, Qi, X, Welham, K J, Gibbons, W A

“…S-Adenosyl-L-methionine (SAM) is a methyl-donor compound which is actively involved in a variety of biochemical reactions. An assay has been developed…”
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