Search Results - "Weldingh, Karin"

Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals by Tourdot, Sophie, Baltrunkonis, Daniel, Denies, Sofie, Devanarayan, Viswanath, Grudzinska-Goebel, Joanna, Kromminga, Arno, Lotz, Gregor P, Malherbe, Laurent, Michaut, Lydia, Weldingh, Karin N, Pedras-Vasconcelos, Joao A, Salazar-Fontana, Laura I, Spindeldreher, Sebastian, Sauna, Zuben, Snoeck, Veerle, Verthelyi, Daniela, Kramer, Daniel

“…Biologics have revolutionized disease management in many therapeutic areas by addressing unmet medical needs and overcoming resistance to standard-of-care…”
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Comparison of Tuberculin Skin Test and New Specific Blood Test in Tuberculosis Contacts by Brock, Inger, Weldingh, Karin, Lillebaek, Troels, Follmann, Frank, Andersen, Peter

“…The tuberculin skin test used to detect latent Mycobacterium tuberculosis infection has many drawbacks, and a new diagnostic test for latent tuberculosis…”
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Commercial serological antibody detection tests for the diagnosis of pulmonary tuberculosis: a systematic review by Steingart, Karen R, Henry, Megan, Laal, Suman, Hopewell, Philip C, Ramsay, Andrew, Menzies, Dick, Cunningham, Jane, Weldingh, Karin, Pai, Madhukar

“…The global tuberculosis epidemic results in nearly 2 million deaths and 9 million new cases of the disease a year. The vast majority of tuberculosis patients…”
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A novel next‐generation FVIIIa mimetic, Mim8, has a favorable safety profile and displays potent pharmacodynamic effects: Results from safety studies in cynomolgus monkeys by Lauritzen, Brian, Bjelke, Mads, Björkdahl, Olle, Bloem, Esther, Keane, Kevin, Kjalke, Marianne, Rossen, Marie, Lippert, Solvej Lund, Weldingh, Karin Nana, Skydsgaard, Mikala, Kjellev, Stine

“…Background Mim8 is a novel, next‐generation factor VIIIa mimetic in development for subcutaneous prophylactic treatment of patients with hemophilia A with and…”
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ESAT-6/CFP10 skin test predicts disease in M. tuberculosis-infected guinea pigs by Weldingh, Karin, Andersen, Peter

“…Targeted preventive chemotherapy of individuals with progressive subclinical (incipient) disease before it becomes contagious would break the chain of…”
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CTLA4‐Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats by Øvlisen, Gabi Overgaard, Thygesen, Peter, Weldingh, Karin Nana, Bloem, Esther, Skov, Søren, Almholt, Kasper, Lövgren, Karin Maria, Ley, Carsten Dan, Holm, Thomas Lindebo

“…Introduction Immunogenicity causing development of anti‐drug antibodies (ADAs) are major challenges in the treatment of haemophilia, as well as other diseases…”
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Prospective evaluation of a whole-blood test using Mycobacterium tuberculosis-specific antigens ESAT-6 and CFP-10 for diagnosis of active tuberculosis by Ravn, Pernille, Munk, Martin E, Andersen, Ase B, Lundgren, Bettina, Lundgren, Jens D, Nielsen, Lars N, Kok-Jensen, Axel, Andersen, Peter, Weldingh, Karin

“…A new immunodiagnostic test based on the Mycobacterium tuberculosis-specific antigens CFP-10/ESAT-6(QFT-RD1) has been launched as an aid in the diagnosis of…”
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Specific T-Cell Epitopes for Immunoassay-Based Diagnosis of Mycobacterium tuberculosis Infection by BROCK, Inger, WELDINGH, Karin, LEYTEN, Eliane M. S, AREND, Sandra M, RAVN, Pernille, ANDERSEN, Peter

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Assessing the Serodiagnostic Potential of 35 Mycobacterium tuberculosis Proteins and Identification of Four Novel Serological Antigens by Weldingh, Karin, Rosenkrands, Ida, Okkels, Limei Meng, Doherty, T. Mark, Andersen, Peter

“…Improved diagnostic reagents are needed for the detection of Mycobacterium tuberculosis infections, and the development of a serodiagnostic test would…”
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Evaluation of Mycobacterium tuberculosis-Specific Antibody Responses in Populations with Different Levels of Exposure from Tanzania, Ethiopia, Brazil, and Denmark by Hoff, Soren T., Abebe, Markos, Ravn, Pernille, Range, Nyagosya, Malenganisho, Wabyahe, Rodriques, Denise S., Kallas, Esper G., Søborg, Christian, Doherty, T. Mark, Andersen, Peter, Weldingh, Karin

“…Background. New, simple, and better-performing diagnostic tools are needed for the diagnosis of tuberculosis (TB). Much effort has been invested in developing…”
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FVIII Inhibitors can Accurately be Measured in the Presence of Mim8 in Hemophilia A Plasma by Pickering, William, Weldingh, Karin, Robinson, Mary, Cogswell, Caroline, Ezban, Mirella

“…Introduction: Mim8 (Denecimig; Novo Nordisk) is a next generation bispecific antibody being developed for prophylactic treatment of hemophilia A with or…”
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Use of Enzyme-Linked Immunospot Assay with Mycobacterium tuberculosis- Specific Peptides for Diagnosis of Recent Infection with M. tuberculosis after Accidental Laboratory Exposure by Leyten, Eliane M. S, Mulder, Bert, Prins, Corine, Weldingh, Karin, Andersen, Peter, Ottenhoff, Tom H. M, van Dissel, Jaap T, Arend, Sandra M

“…This report of an accidental exposure to Mycobacterium tuberculosis in a microbiological laboratory illustrates the value of gamma interferon enzyme-linked…”
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Correction: Commercial Serological Antibody Detection Tests for the Diagnosis of Pulmonary Tuberculosis: A Systematic Review by Steingart, Karen R, Henry, Megan, Laal, Suman, Hopewell, Philip C, Ramsay, Andrew, Menzies, Dick, Cunningham, Jane, Weldingh, Karin, Pai, Madhukar

“…(2007) Correction: Commercial Serological Antibody Detection Tests for the Diagnosis of Pulmonary Tuberculosis: A Systematic Review…”
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Human T‐cell responses to the RD1‐encoded protein TB27.4 (Rv3878) from Mycobacterium tuberculosis by Agger, Else Marie, Brock, Inger, Okkels, Limei Meng, Arend, Sandra M., Aagaard, Claus S., Weldingh, Karin N., Andersen, Peter

“…Summary In recent years, there has been considerable focus on the discovery and characterization of proteins derived from Mycobacterium tuberculosis leading to…”
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Replacing the tuberculin skin test with a specific blood test by Weldingh, Karin, Andersen, Peter

“…For almost 100 years has the tuberculin skin test (TST) been used for the support the diagnosis of active and latent TB infection. The TST test has, however, a…”
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Metabolite changes in blood predict the onset of tuberculosis by Weiner, January, Maertzdorf, Jeroen, Sutherland, Jayne S., Duffy, Fergal J., Thompson, Ethan, Suliman, Sara, McEwen, Gayle, Thiel, Bonnie, Parida, Shreemanta K., Zyla, Joanna, Hanekom, Willem A., Mohney, Robert P., Boom, W. Henry, Mayanja-Kizza, Harriet, Howe, Rawleigh, Dockrell, Hazel M., Ottenhoff, Tom H. M., Scriba, Thomas J., Zak, Daniel E., Walzl, Gerhard, Kaufmann, Stefan H. E.

“…New biomarkers of tuberculosis (TB) risk and disease are critical for the urgently needed control of the ongoing TB pandemic. In a prospective multisite study…”
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Proteomic Profiling of Mycobacterium tuberculosis Identifies Nutrient-starvation-responsive Toxin–antitoxin Systems by Albrethsen, Jakob, Agner, Jeppe, Piersma, Sander R., Højrup, Peter, Pham, Thang V., Weldingh, Karin, Jimenez, Connie R., Andersen, Peter, Rosenkrands, Ida

“…In order to successfully enter the latent stage, Mycobacterium tuberculosis must adapt to conditions such as nutrient limitation and hypoxia. In vitro models…”
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T cell receptor repertoires associated with control and disease progression following Mycobacterium tuberculosis infection by Musvosvi, Munyaradzi, Huang, Huang, Wang, Chunlin, Xia, Qiong, Rozot, Virginie, Krishnan, Akshaya, Acs, Peter, Cheruku, Abhilasha, Obermoser, Gerlinde, Leslie, Alasdair, Behar, Samuel M., Hanekom, Willem A., Bilek, Nicole, Fisher, Michelle, Kaufmann, Stefan H. E., Walzl, Gerhard, Hatherill, Mark, Davis, Mark M., Scriba, Thomas J.

“…Antigen-specific, MHC-restricted αβ T cells are necessary for protective immunity against Mycobacterium tuberculosis , but the ability to broadly study these…”
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The prognosis of latent tuberculosis: can disease be predicted? by Andersen, Peter, Doherty, T. Mark, Pai, Madhukar, Weldingh, Karin

“…In humans, Mycobacterium tuberculosis persists for long periods in a clinically latent state, creating a huge reservoir of 'silent’ tuberculosis (TB) (roughly…”
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Intravenous Administration of Recombinant Factor VIII Induces Immune Tolerance to Subcutaneous Turoctocog Alfa Pegol (SC N8-GP) in Humanized Hemophilia A Mice by Reedtz-Runge, Stine Louise, Weldingh, Karin, Schiøler Schultz, Heidi, Holm Millner, Anders, Rode, Frederik, Wiinberg, Bo, Kjelgaard-Hansen, Mads

“…Introduction Turoctocog alfa pegol (N8-GP) is a glycoPEGylated recombinant factor VIII (rFVIII) under development for treatment of hemophilia A (HA). Patients…”
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