Search Results - "Welcsh, Piri L."

CTCF physically links cohesin to chromatin by Rubio, Eric D, Reiss, David J, Welcsh, Piri L, Disteche, Christine M, Filippova, Galina N, Baliga, Nitin S, Aebersold, Ruedi, Ranish, Jeffrey A, Krumm, Anton

“…Cohesin is required to prevent premature dissociation of sister chromatids after DNA replication. Although its role in chromatid cohesion is well established,…”
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A genomewide screen for suppressors of Alu-mediated rearrangements reveals a role for PIF1 by Chisholm, Karen M, Aubert, Sarah D, Freese, Krister P, Zakian, Virginia A, King, Mary-Claire, Welcsh, Piri L

“…Alu-mediated rearrangement of tumor suppressor genes occurs frequently during carcinogenesis. In breast cancer, this mechanism contributes to loss of the…”
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Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation by DelloRusso, Christiana, Welcsh, Piri L, Wang, Weixin, Garcia, Rochelle L, King, Mary-Claire, Swisher, Elizabeth M

“…The breast and ovarian cancer susceptibility gene BRCA1 plays a major role in the DNA damage response pathway. The lack of well-characterized human BRCA1-null…”
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BRCA1 Transcriptionally Regulates Genes Involved in Breast Tumorigenesis by Welcsh, Piri L., Lee, Ming K., Gonzalez-Hernandez, Rachel M., Black, Daniel J., Mahadevappa, Mamatha, Swisher, Elizabeth M., Warrington, Janet A., King, Mary-Claire

“…Loss of function of BRCA1 caused by inherited mutation and tissue-specific somatic mutation leads to breast and ovarian cancer. Nearly all BRCA1 germ-line…”
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The impact of germline testing for hereditary cancer postdiagnosis by Owens, Kelly, Schlager, Lisa, Welcsh, Piri L

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Experiences of genetic counselors in referring young and metastatic breast cancer patients to support services: A needs assessment by Clark, Elizabeth Bourquardez, Bonini, Katherine E., Pugh Yi, Robin H., Kuhn, Erica, Klemp, Jennifer R., Rose, Diane, Owens, Kelly N., Welcsh, Piri L., Conaty, Jessica, Duquette, Debra, Friedman, Susan J., Dean, Marleah

“…OBJECTIVEConduct a needs assessment to explore the experiences, barriers, and needs of genetic counselors (GCs), who counsel and refer young and metastatic…”
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Insights into the functions of BRCA1 and BRCA2 by Welcsh, Piri L, Owens, Kelly N, King, Mary-Claire

“…Since BRCA1 and BRCA2 were cloned five years ago, unraveling their normal functions has posed fascinating problems for cancer biologists. Both genes are novel,…”
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Nonsyndromic Deafness DFNA1 Associated with Mutation of a Human Homolog of the Drosophila Gene diaphanous by Lynch, Eric D., Lee, Ming K., Morrow, Jan E., Welcsh, Piri L., León, Pedro E., King, Mary-Claire

“…The gene responsible for autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive hearing loss in a large Costa Rican kindred was previously…”
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Cancer Taking up iodide in breast tissue by Welcsh, Piri L, Mankoff, David A

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Taking up iodide in breast tissue by Welcsh, P L, Mankoff, D A

“…Writing in "Nature Medicine," Tazebay, Wapnir and colleagues show that the sodium-iodide symporter (NIS) is also responsible for iodide transport into…”
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Inherited breast cancer: an emerging picture by Welcsh, Piri L, Schubert, Elizabeth L, King, Mary-Claire

“…A role for BRCA1 and BRCA2 in the control of genome integrity easily fits a tumor suppressor model. It is well established that mutations in DNA repair genes…”
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BRCA1 and BRCA2 and the genetics of breast and ovarian cancer by Welcsh, P L, King, M C

“…Germline mutations in the tumor suppressor genes BRCA1 and BRCA2 predispose individuals to breast and ovarian cancers. Progress in determining the function of…”
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Characterization ofEZH1,a Human Homolog ofDrosophila Enhancer of zestenearBRCA1 by Abel, Kenneth J., Brody, Lawrence C., Valdes, John M., Erdos, Michael R., Mckinley, Dawn R., Castilla, Lucio H., Merajver, Sofia D., Couch, Fergus J., Friedman, Lori S., Ostermeyer, Elizabeth A., Lynch, Eric D., King, Mary-Claire, Welcsh, Piri L., Osborne-Lawrence, Sherri, Spillman, Monique, Bowcock, Anne M., Collins, Francis S., Weber, Barbara L.

“…Recent transcription mapping efforts within chromosome 17q21 have led to the identification of a human homolog of theDrosophilageneEnhancer of zeste, E(z). A…”
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BRCA1 and BRCA2 and the genetics of breast and ovarian cancer: Reviews on molecular genetics of cancer by WELCSH, Piri L, KING, Mary-Claire

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Characterization of EZH1, a human homolog of Drosophila enhancer of zeste near BRCA1 by ABEL, K. J, BRODY, L. C, LYNCH, E. D, KING, M.-C, WELCSH, P. L, OSBORNE-LAWRENCE, S, SPILLMAN, M, BOWCOCK, A. M, COLLINS, F. S, WEBER, B. L, VALDES, J. M, ERDOS, M. R, MCKINLEY, D. R, CASTILLA, L. H, MERAJVER, S. D, COUCH, F. J, FRIEDMAN, L. S, OSTERMEYER, E. A

“…Recent transcription mapping efforts within chromosome 17q21 have led to the identification of a human homolog of the Drosophila gene Enhancer of zeste, E(z)…”
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Direct selection of expressed sequences within a 1-Mb region flanking BRCA1 on human chromosome 17q21 by Osborne-Lawrence, Sherri, Welcsh, Piri L., Spillman, Monique, Chandrasekharappa, Settara C., Gallardo, Teresa D., Lovett, Michael, Bowcock, Anne M.

“…Direct selection of genes within the interval of chromosome 17q21 containing BRCA1 was performed. YAC and cosmid contigs spanning the BRCA1 region were used to…”
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Purification and N-terminal sequence analysis of pea chloroplast protein synthesis factor EF-G by Akkaya, M S, Welcsh, P L, Wolfe, M A, Duerr, B K, Becktel, W J, Breitenberger, C A

“…Chloroplast protein synthesis elongation factor G (chlEF-G) has been purified from whole-cell extracts of light-induced pea (Pisum sativum) seedlings. The…”
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