Search Results - "Weitzman, Jonathan B"

Host–parasite interactions: an intimate epigenetic relationship by Cheeseman, Kevin, Weitzman, Jonathan B.

“…Summary The epigenetics of host–pathogen interactions is emerging as an interesting angle from which to study how parasites have evolved sophisticated…”
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What’s the Damage? The Impact of Pathogens on Pathways that Maintain Host Genome Integrity by Weitzman, Matthew D., Weitzman, Jonathan B.

“…Maintaining genome integrity and transmission of intact genomes is critical for cellular, organismal, and species survival. Cells can detect damaged DNA,…”
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SMYD3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9 by COCK-RADA, Alicia M, MEDJKANE, Souhila, JANSKI, Natacha, YOUSFI, Nadhir, PERICHON, Martine, CHAUSSEPIED, Marie, CHLUBA, Johanna, LANGSLEY, Gordon, WEITZMAN, Jonathan B

“…Upregulation of the matrix metalloproteinase (MMP)-9 plays a central role in tumor progression and metastasis by stimulating cell migration, tumor invasion,…”
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Theileria parasites sequester host eIF5A to escape elimination by host-mediated autophagy by Villares, Marie, Lourenço, Nelly, Ktorza, Ivan, Berthelet, Jérémy, Panagiotou, Aristeidis, Richard, Aurélie, Amo, Angélique, Koziy, Yulianna, Medjkane, Souhila, Valente, Sergio, Fioravanti, Rossella, Pioche-Durieu, Catherine, Lignière, Laurent, Chevreux, Guillaume, Mai, Antonello, Weitzman, Jonathan B.

“…Intracellular pathogens develop elaborate mechanisms to survive within the hostile environments of host cells. Theileria parasites infect bovine leukocytes and…”
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Dynamic methylation of histone H3K18 in differentiating Theileria parasites by Cheeseman, Kevin, Jannot, Guillaume, Lourenço, Nelly, Villares, Marie, Berthelet, Jérémy, Calegari-Silva, Teresa, Hamroune, Juliette, Letourneur, Franck, Rodrigues-Lima, Fernando, Weitzman, Jonathan B.

“…Lysine methylation on histone tails impacts genome regulation and cell fate determination in many developmental processes. Apicomplexa intracellular parasites…”
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Methylation of ESCRT-III components regulates the timing of cytokinetic abscission by Richard, Aurélie, Berthelet, Jérémy, Judith, Delphine, Advedissian, Tamara, Espadas, Javier, Jannot, Guillaume, Amo, Angélique, Loew, Damarys, Lombard, Berangere, Casanova, Alexandre G., Reynoird, Nicolas, Roux, Aurélien, Berlioz-Torrent, Clarisse, Echard, Arnaud, Weitzman, Jonathan B., Medjkane, Souhila

“…Abscission is the final stage of cytokinesis, which cleaves the intercellular bridge (ICB) connecting two daughter cells. Abscission requires tight control of…”
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OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes by Marsolier, Justine, Pineau, Sandra, Medjkane, Souhila, Perichon, Martine, Yin, Qinyan, Flemington, Erik, Weitzman, Matthew D, Weitzman, Jonathan B

“…The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in…”
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Intracellular Theileria Parasites PIN Down Host Metabolism by Medjkane, Souhila, Weitzman, Jonathan B

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Deciphering AP-1 Function in Tumorigenesis: Fra-ternizing on Target Promoters by Verde, Pasquale, Casalino, Laura, Talotta, Francesco, Yaniv, Moshe, Weitzman, Jonathan B.

“…Multi-gene families of transcription factors pose a formidable challenge to molecular and functional analysis. Dissecting distinct functions for individual…”
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Putative SET-domain methyltransferases in Cryptosporidium parvum and histone methylation during infection by Sawant, Manasi, Benamrouz-Vanneste, Sadia, Meloni, Dionigia, Gantois, Nausicaa, Even, Gaël, Guyot, Karine, Creusy, Colette, Duval, Erika, Wintjens, René, Weitzman, Jonathan B., Chabe, Magali, Viscogliosi, Eric, Certad, Gabriela

“…Cryptosporidium parvum is a leading cause of diarrhoeal illness worldwide being a significant threat to young children and immunocompromised patients, but the…”
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Mutations in the TaPIN1 peptidyl prolyl isomerase gene in Theileria annulata parasites isolated in Sudan by Salim, Bashir, Chatanga, Elisha, Jannot, Guillaume, Mossaad, Ehab, Nakao, Ryo, Weitzman, Jonathan B.

“…The tick-borne parasite Theileria annulata is the causative agent of tropical theileriosis or Mediterranean theileriosis. Infection of bovine leukocytes by the…”
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Epigenetic metaphors: an interdisciplinary translation of encoding and decoding by Raz, Aviad, Pontarotti, Gaëlle, Weitzman, Jonathan B.

“…Looking at the new and often disputed science of epigenetics, we examined the challenges faced by scientists when they communicate scientific research to the…”
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Secreted parasite Pin1 isomerase stabilizes host PKM2 to reprogram host cell metabolism by Marsolier, Justine, Perichon, Martine, Weitzman, Jonathan B., Medjkane, Souhila

“…Metabolic reprogramming is an important feature of host–pathogen interactions and a hallmark of tumorigenesis. The intracellular apicomplexa parasite Theileria…”
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TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility by Chaussepied, Marie, Janski, Natacha, Baumgartner, Martin, Lizundia, Regina, Jensen, Kirsty, Weir, William, Shiels, Brian R, Weitzman, Jonathan B, Glass, Elizabeth J, Werling, Dirk, Langsley, Gordon

“…Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible…”
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Trifloxystrobin blocks the growth of Theileria parasites and is a promising drug to treat Buparvaquone resistance by Villares, Marie, Lourenço, Nelly, Berthelet, Jeremy, Lamotte, Suzanne, Regad, Leslie, Medjkane, Souhila, Prina, Eric, Rodrigues-Lima, Fernando, Späth, Gerald F., Weitzman, Jonathan B.

“…Theileria parasites are responsible for devastating cattle diseases, causing major economic losses across Africa and Asia. Theileria spp. stand apart from…”
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Role of the SMYD3 histone methyltransferase in tumorigenesis: Local or global effects? by Medjkane, Souhila, Cock-Rada, Alicia, Weitzman, Jonathan B.

“…Comment on: Cock-Rada AM, et al. Cancer Res 2011; 72:810-20…”
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Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription by Casalino, Laura, Bakiri, Latifa, Talotta, Francesco, Weitzman, Jonathan B, Fusco, Alfredo, Yaniv, Moshe, Verde, Pasquale

“…Fra‐1 is frequently overexpressed in epithelial cancers and implicated in invasiveness. We previously showed that Fra‐1 plays crucial roles in RAS…”
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A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network by MILED, Chaouki, PONTOGLIO, Marco, GARBAY, Serge, YANIV, Moshe, WEITZMAN, Jonathan B

“…The transcriptional activity of the p53 protein is central to its role in tumor suppression. Identification of the complete repertoire of p53-regulated genes…”
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The clever strategies used by intracellular parasites to hijack host gene expression by Villares, Marie, Berthelet, Jérémy, Weitzman, Jonathan B.

“…Intracellular pathogens need to develop sophisticated mechanisms to survive and thrive in the hostile environment within host cells. Unicellular, eukaryotic…”
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Transcription Factor JunD, Deprived of Menin, Switches from Growth Suppressor to Growth Promoter by Agarwal, Sunita K., Novotny, Elizabeth A., Crabtree, Judy S., Weitzman, Jonathan B., Yaniv, Moshe, Burns, A. Lee, Chandrasekharappa, Settara C., Collins, Francis S., Spiegel, Allen M., Marx, Stephen J.

“…Different components of the AP1 transcription factor complex appear to have distinct effects on cell proliferation and transformation. In contrast to other AP1…”
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