Search Results - "Weist, Michael"

CAR T cells for brain tumors: Lessons learned and road ahead by Akhavan, David, Alizadeh, Darya, Wang, Dongrui, Weist, Michael R., Shepphird, Jennifer K., Brown, Christine E.

“…Malignant brain tumors, including glioblastoma, represent some of the most difficult to treat of solid tumors. Nevertheless, recent progress in immunotherapy,…”
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Low Dose Focused Ultrasound Induces Enhanced Tumor Accumulation of Natural Killer Cells by Sta Maria, Naomi S, Barnes, Samuel R, Weist, Michael R, Colcher, David, Raubitschek, Andrew A, Jacobs, Russell E

“…Natural killer (NK) cells play a vital antitumor role as part of the innate immune system. Efficacy of adoptive transfer of NK cells depends on their ability…”
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HER2 and HLA-A02 dual CAR-T cells utilize LOH in a NOT logic gate to address on-target off-tumor toxicity by Bassan, David, Weinberger, Leehee, Yi, Jason, Kim, Tanya, Weist, Michael R, Adams, Gregor B, Foord, Orit, Chaim, Neta, Tabak, Sarit, Bujanover, Nir, Lopesco, Yael, Vucci, Kristina, Schnair, Caitlin, Levy-Knafo, Limor, Kendall, Richard L, Calzone, Frank J, Sharbi-Yunger, Adi

“…BackgroundOne of the major challenges in chimeric antigen receptor (CAR)-T cell therapy for solid tumors is the potential for on-target off-tumor toxicity due…”
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PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89 Zr-Oxine by Weist, Michael R, Starr, Renate, Aguilar, Brenda, Chea, Junie, Miles, Joshua K, Poku, Erasmus, Gerdts, Ethan, Yang, Xin, Priceman, Saul J, Forman, Stephen J, Colcher, David, Brown, Christine E, Shively, John E

“…Chimeric antigen receptor (CAR) T cell therapy is a promising clinical approach for reducing tumor progression and prolonging patient survival. However,…”
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PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89Zr-Oxine by Weist, Michael R, Starr, Renate, Aguilar, Brenda, Chea, Junie, Miles, Joshua K, Poku, Erasmus, Gerdts, Ethan, Yang, Xin, Priceman, Saul J, man, Stephen J, Colcher, David, Brown, Christine E, Shively, John E

“…Chimeric antigen receptor (CAR) T cell therapy is a promising clinical approach for reducing tumor progression and prolonging patient survival. However,…”
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Diagnostic PET Imaging of Mammary Microcalcifications Using 64Cu-DOTA-Alendronate in a Rat Model of Breast Cancer by Ahrens, Bradley J, Li, Lin, Ciminera, Alexandra K, Chea, Junie, Poku, Erasmus, Bading, James R, Weist, Michael R, Miller, Marcia M, Colcher, David M, Shively, John E

“…The development of improved breast cancer screening methods is hindered by a lack of cancer-specific imaging agents and effective small-animal models to test…”
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Diagnostic PET Imaging of Mammary Microcalcifications Using 64 Cu-DOTA-Alendronate in a Rat Model of Breast Cancer by Ahrens, Bradley J, Li, Lin, Ciminera, Alexandra K, Chea, Junie, Poku, Erasmus, Bading, James R, Weist, Michael R, Miller, Marcia M, Colcher, David M, Shively, John E

“…The development of improved breast cancer screening methods is hindered by a lack of cancer-specific imaging agents and effective small-animal models to test…”
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TGF-[beta]1 enhances contractility in engineered skeletal muscle by Weist, Michael R, Wellington, Michael S, Bermudez, Jacob E, Kostrominova, Tatiana Y, Mendias, Christopher L, Arruda, Ellen M, Larkin, Lisa M

“…Scaffoldless engineered 3D skeletal muscle tissue created from satellite cells offers the potential to replace muscle tissue that is lost due to severe trauma…”
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TGF-β1 enhances contractility in engineered skeletal muscle by Weist, Michael R., Wellington, Michael S., Bermudez, Jacob E., Kostrominova, Tatiana Y., Mendias, Christopher L., Arruda, Ellen M., Larkin, Lisa M.

“…Scaffoldless engineered 3D skeletal muscle tissue created from satellite cells offers the potential to replace muscle tissue that is lost due to severe trauma…”
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442-I Enhancing TCR-T responses and overcoming the tumor microenvironment by combination with a TGFβ-specific CAR by Weist, Michael R, BenDavid, Ethan, Munguia, Melanie L, Reyes, Jessica, Chen, Ximin, Parisi, Giulia, Cui, Jiajia, Foord, Orit, Johnston, Jim

“…BackgroundOvercoming the suppressive tumor microenvironment (TME) remains an important unmet challenge for chimeric antigen receptor (CAR) T cell therapies. A…”
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Diagnostic PET Imaging of Mammary Microcalcifications Using ^sup 64^Cu-DOTA-Alendronate in a Rat Model of Breast Cancer by Ahrens, Bradley J, Li, Lin, Ciminera, Alexandra K, Chea, Junie, Poku, Erasmus, Bading, James R, Weist, Michael R, Miller, Marcia M, Colcher, David M, Shively, John E

“…The development of improved breast cancer screening methods is hindered by a lack of cancer-specific imaging agents and effective small-animal models to test…”
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PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with ^sup 89^Zr-Oxine by Miles, Joshua K, Poku, Erasmus, Gerdts, Ethan, Yang, Xin, Priceman, Saul J, man, Stephen J, Colcher, David, Brown, Christine E, Shively, John E, Weist, Michael R, Aguilar, Brenda, Starr, Renate, Chea, Junie

“…Chimeric antigen receptor (CAR) T cell therapy is a promising clinical approach for reducing tumor progression and prolonging patient survival. However,…”
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316 Next generation CAR-T incorporating an inhibitory CAR (iCAR) for increased safety in solid tumors by Bassan, David, Weist, Michael, Weinberger, Leehee, Yi, Jason, Adams, Gregor, Kim, Tanya, Schnair, Caitlin, Vucci, Kristina, Tabak, Sarit, Neta Chaim, Bujanover, Nir, Lopesco, Yael, Levy-Kanfo, Limor, Foord, Orit, Johnston, Jim, Calzone, Frank, Kendell, Rick, Sharbi-Yunger, Adi

“…BackgroundChimeric antigen receptor (CAR)-T cell therapy has shown incredible clinical success for hematopoietic malignancies, but for solid tumors is limited…”
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Abstract 2848: Incorporation of inhibitory signaling domains into chimeric antigen receptors (iCAR) designed for self-regulation of canonical CAR-T to treat solid tumors by Bassan, David, Yi, Jason, Chaim, Neta, Bujanover, Nir, Tabak, Sarit, Kim, Tanya, Lopesco, Yael, Weinberger, Leehee, Vucci, Kristina, Weist, Michael, Schnair, Caitlin, Adams, Gregor B., Foord, Orit, Calzone, Frank J., Kendall, Rick, Sharbi-Yunger, Adi

“…Abstract Chimeric antigen receptor (CAR)-T cell therapy is a groundbreaking cancer treatment that has produced remarkable clinical efficacy for hematopoietic…”
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Abstract 2826: Rewiring CAR T-cells for absolute solid tumor specificity and safety by Weist, Michael R., Sharbi-Yunger, Adi, Yi, Jason, Schnair, Caitlin, Bassan, David, Kim, Tanya, Tabak, Sarit, Lopesco, Yael, Weinberger, Leehee, Bujanover, Nir, Chaim, Neta, Vucci, Kristina, Foord, Orit, Calzone, Frank J., Kendall, Rick, Adams, Gregor B.

“…Abstract Translation of the unprecedented efficacy of chimeric antigen receptor (CAR) T-cell technology into solid tumors requires a solution to the problem of…”
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Developing and Evaluating Radiolabeling Agents for Imaging Cells with Positron Emission Tomography by Weist, Michael Ryan

“…Early clinical studies indicate that treatments with engineered chimeric antigen receptor (CAR) T cells and natural killer (NK) cells are effective in…”
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Low Dose Focused Ultrasound Induces Enhanced Tumor Accumulation of Natural Killer Cells: e0142767 by Maria, Naomi SSta, Barnes, Samuel R, Weist, Michael R, Colcher, David, Raubitschek, Andrew A, Jacobs, Russell E

“…Natural killer (NK) cells play a vital antitumor role as part of the innate immune system. Efficacy of adoptive transfer of NK cells depends on their ability…”
Get full text

TGF-β1 enhances contractility in engineered skeletal muscle: Effect of TGF-β1 on Engineered Skeletal Muscle by Weist, Michael R., Wellington, Michael S., Bermudez, Jacob E., Kostrominova, Tatiana Y., Mendias, Christopher L., Arruda, Ellen M., Larkin, Lisa M.

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