Search Results - "Weissenrieder, Jillian S"
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The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells
Published in Pharmacology (01-01-2020)“…Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult to treat because most anticancer…”
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2
Inhibiting geranylgeranyl diphosphate synthesis reduces nuclear androgen receptor signaling and neuroendocrine differentiation in prostate cancer cell models
Published in The Prostate (01-01-2019)“…Background Following androgen deprivation for the treatment of advanced adenocarcinoma of the prostate, tumors can progress to neuroendocrine prostate cancer…”
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3
Therapeutic Potential of 5'-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma
Published in Viruses (23-08-2022)“…Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer predominantly caused by the human Merkel cell polyomavirus (MCPyV). Treatment for MCC…”
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4
The mitochondrial Ca2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
Published in Frontiers in cell and developmental biology (08-06-2023)“…Introduction: The mitochondrial uniporter (MCU) Ca 2+ ion channel represents the primary means for Ca 2+ uptake by mitochondria. Mitochondrial matrix Ca 2+…”
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5
Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium‐dependent, non‐D2 receptor‐dependent, manner
Published in Pharmacology research & perspectives (01-05-2021)“…Dopamine D2‐like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers…”
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6
Cancer and the Dopamine D 2 Receptor: A Pharmacological Perspective
Published in The Journal of pharmacology and experimental therapeutics (01-07-2019)“…The dopamine D receptor (D R) family is upregulated in many cancers and tied to stemness. Reduced cancer risk has been correlated with disorders such as…”
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7
Schweinfurthins: Lipid Modulators with Promising Anticancer Activity
Published in Lipids (01-08-2018)“…The schweinfurthin family of compounds displays exciting potent and differential cytotoxicity against human cancer cell lines. Currently, the effect of…”
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8
Antipsychotic drugs elicit cytotoxicity in glioblastoma multiforme in a calcium-dependent, non-D 2 receptor-dependent, manner
Published in Pharmacology research & perspectives (01-05-2021)“…Dopamine D -like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers…”
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9
Abstract PO-026: The mitochondrial calcium uniporter contributes to PDAC development and invasion
Published in Cancer research (Chicago, Ill.) (15-11-2020)“…Abstract Pancreatic ductal adenocarcinoma (PDAC) has an exceptionally poor prognosis, with about 50,000 new cases and 45,000 deaths each year. While novel…”
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10
A recurrent missense variant in ITPR3 causes demyelinating Charcot-Marie-Tooth with variable severity
Published in Brain (London, England : 1878) (28-06-2024)“…Charcot-Marie-Tooth (CMT) disease is a neuromuscular disorder affecting the peripheral nervous system. The diagnostic yield in demyelinating CMT (CMT1) is…”
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Abstract C113: The mitochondrial calcium uniporter supports epithelial to mesenchymal transition of pancreatic ductal adenocarcinoma
Published in Cancer research (Chicago, Ill.) (16-01-2024)“…Abstract In spite of many new developments in cancer treatments and targeted therapies over the past few decades, outcomes for pancreatic ductal adenocarcinoma…”
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12
The mitochondrial Ca 2+ channel MCU is critical for tumor growth by supporting cell cycle progression and proliferation
Published in Frontiers in cell and developmental biology (2023)“…The mitochondrial uniporter (MCU) Ca ion channel represents the primary means for Ca uptake by mitochondria. Mitochondrial matrix Ca plays critical roles in…”
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Journal Article -
13
Dopamine D2 Receptor Antagonists as Potential Therapeutics for Glioblastoma Multiforme
Published 01-01-2019“…Recent reports have suggested that dopamine D2 receptor antagonists may have potential to be repurposed as anticancer therapeutics. These compounds, including…”
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