Search Results - "Weissbach, H"
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BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy
Published in iScience (24-07-2020)“…Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans…”
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Protective effects of taurine against oxidative stress in the heart of MsrA knockout mice
Published in Journal of cellular biochemistry (01-11-2012)“…Taurine has been shown to have potent anti‐oxidant properties under various pathophysiological conditions. We reported previously a cellular dysfunction and…”
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3
Sulindac induces differentiation of glioblastoma stem cells making them more sensitive to oxidative stress
Published in Neoplasma (01-01-2018)“…Glioblastoma tumors (GBM) are very heterogeneous, being comprised of several cell subtypes, including glioblastoma stem cells (GSC). These tumors have a high…”
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BK Polyomavirus MicroRNA Levels in Exosomes Are Modulated by Non-Coding Control Region Activity and Down-Regulate Viral Replication When Delivered to Non-Infected Cells Prior to Infection
Published in Viruses (30-08-2018)“…In immunosuppressed patients, -variants emerge carrying rearranged non-coding control-regions ( ) that increase early viral gene region (EVGR) expression and…”
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Structural implications of BK polyomavirus sequence variations in the major viral capsid protein Vp1 and large T-antigen: a computational study
Published in mSphere (23-04-2024)“…BK polyomavirus (BKPyV) is a double-stranded DNA virus causing nephropathy, hemorrhagic cystitis, and urothelial cancer in transplant patients. The…”
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Peptide Methionine Sulfoxide Reductase: Structure, Mechanism of Action, and Biological Function
Published in Archives of Biochemistry and Biophysics (15-01-2002)“…Reactive oxygen and nitrogen intermediates can cause damage to many cellular components and have been implicated in a number of diseases. Cells have developed…”
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MsrA protects cardiac myocytes against hypoxia/reoxygenation induced cell death
Published in Biochemical and biophysical research communications (15-02-2008)“…Reactive oxygen species (ROS) are critical in tissue responses to ischemia–reperfusion. The enzyme methionine sulfoxide reductase-A (MsrA) is capable of…”
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Cloning and Expression of a Mammalian Gene Involved in the Reduction of Methionine Sulfoxide Residues in Proteins
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-1996)“…An enzyme that reduces methionine sulfoxide [Met(O)] residues in proteins [peptide Met(O) reductase (MsrA), EC 1.8.4.6; originally identified in Escherichia…”
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Molecular Characterization of BK Polyomavirus Replication in Allogeneic Hematopoietic Cell Transplantation Patients
Published in The Journal of infectious diseases (12-04-2023)“…Abstract Background High-level BK polyomavirus (BKPyV) replication in allogeneic hematopoietic cell transplantation (HCT) predicts failing immune control and…”
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Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping
Published in Journal of medical virology (01-02-2023)“…Human papillomavirus (HPV) infections are often asymptomatic, but some of the >200 HPV genotypes confer a high risk for precancerous cervical lesions and…”
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Novel Human Polyomavirus Noncoding Control Regions Differ in Bidirectional Gene Expression according to Host Cell, Large T-Antigen Expression, and Clinically Occurring Rearrangements
Published in Journal of virology (01-04-2018)“…ABSTRACT Human polyomavirus (HPyV) DNA genomes contain three regions denoted the early viral gene region (EVGR), encoding the regulatory T-antigens and one…”
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Structure and Mechanism of Peptide Methionine Sulfoxide Reductase, an “Anti-Oxidation” Enzyme
Published in Biochemistry (Easton) (07-11-2000)“…Peptide methionine sulfoxide reductase (MsrA) reverses oxidative damage to both free methionine and methionine within proteins. As such, it helps protect the…”
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Ecdysone induction of MsrA protects against oxidative stress in Drosophila
Published in Biochemical and biophysical research communications (09-03-2007)“…The methionine sulfoxide reductases MsrA and MsrB reduce Met(O) to Met in epimer-specific fashion. In Drosophila, the major ecdysone induced protein is MsrA,…”
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Escherichia coli peptide methionine sulfoxide reductase gene: regulation of expression and role in protecting against oxidative damage
Published in Journal of Bacteriology (01-02-1995)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Gene structure, localization and role in oxidative stress of methionine sulfoxide reductase A (MSRA) in the monkey retina
Published in Experimental eye research (01-05-2006)“…MSRA (EC 1.8.4.6) is a member of the methionine sulfoxide reductase family that can reduce methionine sulfoxide (MetO) in proteins. This repair function has…”
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BK Polyomavirus‐Specific 9mer CD8 T Cell Responses Correlate With Clearance of BK Viremia in Kidney Transplant Recipients: First Report From the Swiss Transplant Cohort Study
Published in American journal of transplantation (01-10-2017)“…BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1–15% of patients. Because antivirals are lacking, most programs screen for…”
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Comparison of Two Commercial Tick-Borne Encephalitis Virus IgG Enzyme-Linked Immunosorbent Assays
Published in Clinical and vaccine immunology (01-07-2015)“…Despite the availability of protective vaccines, tick-borne encephalitis virus (TBEV) infections have been increasingly reported to the European Centre for…”
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JC polyomavirus‐specific antibody responses in pediatric kidney transplant recipients
Published in Pediatric transplantation (01-12-2019)“…BKPyV is widely recognized in KTRs, but little is known about rates of primary and secondary JCPyV exposure in pediatric KTRs. We evaluated JCPyV exposure in…”
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Regulation of methionine synthesis in Escherichia coli
Published in Molecular microbiology (01-07-1991)“…The biosynthesis of methionine in Escherichia coli is under complex regulation. The repression of the biosynthetic pathway by methionine is mediated by a…”
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Seroprevalence of hepatitis E virus (HEV) in a general adult population in Northern Norway: the Tromsø study
Published in Medical microbiology and immunology (01-12-2019)“…Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in many parts of the world but only a few cases have been diagnosed in Norway. To investigate…”
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