Search Results - "Weiss, Vivian L."

Engineering functional 3-dimensional patient-derived endocrine organoids for broad multiplatform applications by Baregamian, Naira, Sekhar, Konjeti R., Krystofiak, Evan S., Vinogradova, Maria, Thomas, Giju, Mannoh, Emmanuel, Solórzano, Carmen C., Kiernan, Colleen M., Mahadevan-Jansen, Anita, Abumrad, Naji, Freeman, Michael L., Weiss, Vivian L., Rathmell, Jeffrey C., Rathmell, W. Kimryn

“…Recent advancements in 3-dimensional patient-derived organoid models have revolutionized the field of cancer biology. There is an urgent need for development…”
Get full text

Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis by Bechard, Matthew E., Smalling, Rana, Hayashi, Akimasa, Zhong, Yi, Word, Anna E., Campbell, Sydney L., Tran, Amanda V., Weiss, Vivian L., Iacobuzio-Donahue, Christine, Wellen, Kathryn E., McDonald, Oliver G.

“…Although metastasis is the most common cause of cancer deaths, metastasis-intrinsic dependencies remain largely uncharacterized. We previously reported that…”
Get full text

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling by Ng, Victoria H., Spencer, Zachary, Neitzel, Leif R., Nayak, Anmada, Loberg, Matthew A., Shen, Chen, Kassel, Sara N., Kroh, Heather K., An, Zhenyi, Anthony, Christin C., Bryant, Jamal M., Lawson, Amanda, Goldsmith, Lily, Benchabane, Hassina, Hansen, Amanda G., Li, Jingjing, D’Souza, Starina, Lebensohn, Andres M., Rohatgi, Rajat, Weiss, William A., Weiss, Vivian L., Williams, Charles, Hong, Charles C., Robbins, David J., Ahmed, Yashi, Lee, Ethan

“…The relative abundance of Wnt receptors plays a crucial role in controlling Wnt signaling in tissue homeostasis and human disease. While the ubiquitin ligases…”
Get full text

Fine-Needle Aspiration-Based Patient-Derived Cancer Organoids by Vilgelm, Anna E., Bergdorf, Kensey, Wolf, Melissa, Bharti, Vijaya, Shattuck-Brandt, Rebecca, Blevins, Ashlyn, Jones, Caroline, Phifer, Courtney, Lee, Mason, Lowe, Cindy, Hongo, Rachel, Boyd, Kelli, Netterville, James, Rohde, Sarah, Idrees, Kamran, Bauer, Joshua A., Westover, David, Reinfeld, Bradley, Baregamian, Naira, Richmond, Ann, Rathmell, W. Kimryn, Lee, Ethan, McDonald, Oliver G., Weiss, Vivian L.

“…Patient-derived cancer organoids hold great potential to accurately model and predict therapeutic responses. Efficient organoid isolation methods that minimize…”
Get full text

Obtaining patient-derived cancer organoid cultures via fine-needle aspiration by Phifer, Courtney J., Bergdorf, Kensey N., Bechard, Matthew E., Vilgelm, Anna, Baregamian, Naira, McDonald, Oliver G., Lee, Ethan, Weiss, Vivian L.

“…Patient-derived tumor organoid cultures are an essential and innovative methodology for translational research. However, current techniques to establish these…”
Get full text

Proximity of immune and tumor cells underlies response to BRAF/MEK-targeted therapies in metastatic melanoma patients by Yan, Chi, Chen, Sheau-Chiann, Ayers, Gregory D., Nebhan, Caroline A., Roland, Joseph T., Weiss, Vivian L., Johnson, Douglas B., Richmond, Ann

“…Acquired resistance to BRAF/MEK-targeted therapy occurs in the majority of melanoma patients that harbor BRAF mutated tumors, leading to relapse or progression…”
Get full text

Trafficking of high avidity HER-2/neu-specific T cells into HER-2/neu-expressing tumors after depletion of effector/memory-like regulatory T cells by Weiss, Vivian L, Lee, Timothy H, Song, Hong, Kouo, Theodore S, Black, Chelsea M, Sgouros, George, Jaffee, Elizabeth M, Armstrong, Todd D

“…Cancer vaccines are designed to activate and enhance cancer-antigen-targeted T cells that are suppressed through multiple mechanisms of immune tolerance in…”
Get full text

Immunofluorescent staining of cancer spheroids and fine-needle aspiration-derived organoids by Bergdorf, Kensey N., Phifer, Courtney J., Bechard, Matthew E., Lee, Mason A., McDonald, Oliver G., Lee, Ethan, Weiss, Vivian L.

“…Our organoid generation technique has allowed for the development of downstream organoid applications. Here, we detail an accessible, straightforward protocol…”
Get full text

Papillary thyroid carcinoma behavior: clues in the tumor microenvironment by Bergdorf, Kensey, Ferguson, Donna C, Mehrad, Mitra, Ely, Kim, Stricker, Thomas, Weiss, Vivian L

“…The prevalence of thyroid carcinoma is increasing and represents the most common endocrine malignancy, with papillary thyroid carcinoma (PTC) being the most…”
Get full text

Incidental Pulmonary Metastases Revealing Subcentimeter Papillary Thyroid Carcinoma by Hu, Ruey, Xu, George, Stricker, Thomas, Li, Bingshan, Weiss, Vivian L., Bischoff, Lindsay

“…Here we present 2 cases of papillary thyroid microcarcinomas (PMCs) that had metastasized at presentation. The 2015 American Thyroid Association and the…”
Get full text

Wnt signalosomes: What we know that we do not know by Hartmann, Heather, Siddiqui, Ghalia Saad, Bryant, Jamal, Robbins, David J., Weiss, Vivian L., Ahmed, Yashi, Lee, Ethan

“…Abstract Signaling through the Wnt/β‐catenin pathway is relayed through three multiprotein complexes: (1) the membrane‐associated signalosome, which includes…”
Get full text

Myxoinflammatory Fibroblastic Sarcoma in Children and Adolescents: Clinicopathologic Aspects of a Rare Neoplasm by Weiss, Vivian L., Antonescu, Cristina R., Alaggio, Rita, Cates, Justin M., Gaskin, David, Stefanovici, Camelia, Coffin, Cheryl M.

“…Myxoinflammatory fibroblastic sarcoma (MIFS), originally described as a low-grade malignant soft-tissue tumor in adults, has recently been reported in children…”
Get full text

Targeting the right regulatory T-cell population for tumor immunotherapy by Weiss, Vivian L., Lee, Timothy H., Jaffee, Elizabeth M., Armstrong, Todd D.

“…Regulatory T cells (Tregs) that suppress tumor-specific T cell-mediated immune responses are the subject of an intense wave of investigation. We recently…”
Get full text

Wnt Signaling in the Phenotype and Function of Tumor-Associated Macrophages by Tigue, Megan L, Loberg, Matthew A, Goettel, Jeremy A, Weiss, William A, Lee, Ethan, Weiss, Vivian L

“…Tumor-associated macrophages (TAM) play an important role in supporting tumor growth and suppressing antitumor immune responses, and TAM infiltration has been…”
Get full text

New terminology—noninvasive follicular neoplasm with papillary-like nuclear features (NIFTP) and its effect on the rate of malignancy at a single institution by Kiernan, Colleen M., Weiss, Vivian L., Mehrad, Mitra, Ely, Kim, Baregamian, Naira, Solórzano, Carmen C.

“…The cytologic qualities of noninvasive follicular neoplasm with papillary-like nuclear features mimic papillary thyroid carcinoma (PTC) on fine-needle…”
Get full text

Instrument Gauge and Type in Uveal Melanoma Fine Needle Biopsy: Implications for Diagnostic Yield and Molecular Prognostication by Klofas, Lindsay K., Bogan, Carley M., Coogan, Alice C., Schultenover, Stephen J., Weiss, Vivian L., Daniels, Anthony B.

“…To systematically evaluate and compare the effects of using small-gauge needles and vitrectors on the ability to obtain adequate diagnostic and prognostic…”
Get full text

BCL-xL inhibition potentiates cancer therapies by redirecting the outcome of p53 activation from senescence to apoptosis by Bharti, Vijaya, Watkins, Reese, Kumar, Amrendra, Shattuck-Brandt, Rebecca L., Mossing, Alexis, Mittra, Arjun, Shen, Chengli, Tsung, Allan, Davies, Alexander E., Hanel, Walter, Reneau, John C., Chung, Catherine, Sizemore, Gina M., Richmond, Ann, Weiss, Vivian L., Vilgelm, Anna E.

“…Cancer therapies trigger diverse cellular responses, ranging from apoptotic death to acquisition of persistent therapy-refractory states such as senescence…”
Get full text

USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling by Kassel, Sara, Hanson, Alison J, Benchabane, Hassina, Saito-Diaz, Kenyi, Cabel, Carly R, Goldsmith, Lily, Taha, Muhammad, Kanuganti, Aksheta, Ng, Victoria H, Xu, George, Ye, Fei, Picker, Julia, Port, Fillip, Boutros, Michael, Weiss, Vivian L, Robbins, David J, Thorne, Curtis A, Ahmed, Yashi, Lee, Ethan

“…The Wnt-β-catenin signal transduction pathway is essential for embryonic development and adult tissue homeostasis. Wnt signaling converts TCF from a…”
Get more information

Racial, ethnic, and socioeconomic disparities in the presentation and management of pediatric thyroid cancer by Sharma, Rahul K., Patel, Siddharth, Gallant, Jean-Nicolas, Esianor, Brandon I., Duffus, Sara, Wang, Huiying, Weiss, Vivian L., Belcher, Ryan H.

“…Disparities across race and socioeconomic status (SES) in cancer treatment exist for many malignancies. Disadvantaged groups have repeatedly been shown to…”
Get full text

Evolving approaches in paediatric thyroid cytopathology: A review by Loberg, Matthew A., Tigue, Megan L., Gallant, Jean‐Nicolas, Wang, Huiying, Canberk, Sule, Weiss, Vivian L.

“…The guidelines for the workup of thyroid nodules have been established in adult populations and secondarily applied to paediatric populations. In particular,…”
Get full text