Search Results - "Weiss, Norbert"

Glycosylation of voltage-gated calcium channels in health and disease by Lazniewska, Joanna, Weiss, Norbert

“…Voltage-gated calcium channels (VGCCs) are transmembrane proteins that translate electrical activities into intracellular calcium elevations and downstream…”
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Rates, management, and outcome of rivaroxaban bleeding in daily care: results from the Dresden NOAC registry by Beyer-Westendorf, Jan, Förster, Kati, Pannach, Sven, Ebertz, Franziska, Gelbricht, Vera, Thieme, Christoph, Michalski, Franziska, Köhler, Christina, Werth, Sebastian, Sahin, Kurtulus, Tittl, Luise, Hänsel, Ulrike, Weiss, Norbert

“…Worldwide, rivaroxaban is increasingly used for stroke prevention in atrial fibrillation and treatment of venous thromboembolism, but little is known about…”
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Pathophysiology of ion channels in amyotrophic lateral sclerosis by Stringer, Robin N, Weiss, Norbert

“…Amyotrophic lateral sclerosis (ALS) stands as the most prevalent and severe form of motor neuron disease, affecting an estimated 2 in 100,000 individuals…”
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Selective inhibition of neuronal Cav3.3 T-type calcium channels by TAT-based channel peptide by Cmarko, Leos, Weiss, Norbert

“…Abstract Low-voltage-activated Ca v 3 calcium channels (T-type) play an essential role in the functioning of the nervous system where they support oscillatory…”
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COMPARE: prospective, randomized, non-inferiority trial of high- vs. low-dose paclitaxel drug-coated balloons for femoropopliteal interventions by Steiner, Sabine, Schmidt, Andrej, Zeller, Thomas, Tepe, Gunnar, Thieme, Marcus, Maiwald, Lars, Schröder, Henrik, Euringer, Wulf, Ulrich, Matthias, Brechtel, Klaus, Brucks, Steffen, Blessing, Erwin, Schuster, Johannes, Langhoff, Ralf, Schellong, Sebastian, Weiss, Norbert, Scheinert, Dierk

“…Drug-coated balloons (DCBs) for femoropopliteal interventions have not been tested against each other. We aimed to directly compare efficacy and safety of a…”
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Cross-talk between TRPML1 channel, lipids and lysosomal storage diseases by Weiss, Norbert

“…Described by the Belgian cytologist Christian De Duve in 1949, 1 lysosomes (from the Greek "digestive bodies") are ubiquitous specialized intracellular…”
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Secretory carrier-associated membrane protein 5 regulates cell-surface targeting of T-type calcium channels by Mustafá, Emilio R, Weiß, Konstantin, Weiss, Norbert

“…Missense mutations in the human secretary carrier-associated membrane protein 5 (SCAMP5) cause a variety of neurological disorders including neurodevelopmental…”
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PLX-PAD Cell Treatment of Critical Limb Ischaemia: Rationale and Design of the PACE Trial by Norgren, Lars, Weiss, Norbert, Nikol, Sigrid, Hinchliffe, Robert J., Lantis, John C., Patel, Manesh R., Reinecke, Holger, Ofir, Racheli, Rosen, Yael, Peres, Dan, Aberman, Zami

“…Critical limb ischaemia (CLI) is a life threatening condition with a considerable risk of major amputation and death. Besides revascularisation, no treatment…”
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Cavβ surface charged residues contribute to the regulation of neuronal calcium channels by Tran-Van-Minh, Alexandra, De Waard, Michel, Weiss, Norbert

“…Abstract Voltage-gated calcium channels are essential regulators of brain function where they support depolarization-induced calcium entry into neurons. They…”
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Predictive factors for better bypass patency and limb salvage after prosthetic above-knee bypass reconstruction by Klingelhoefer, Eric, MD, Bergert, Hendrik, MD, Kersting, Stephan, MD, Ludwig, Stefan, MD, Weiss, Norbert, MD, Schönleben, Frank, MD, Grützmann, Robert, MD, Gäbel, Gabor, MD

“…Background Peripheral arterial disease (PAD) is one of the most underestimated diseases because of its high prevalence and unfavorable prognosis. Many PAD…”
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A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase by Ragavan, Vinitha N., Nair, Pramod C., Jarzebska, Natalia, Angom, Ramcharan Singh, Ruta, Luana, Bianconi, Elisa, Grottelli, Silvia, Tararova, Natalia D., Ryazanskiy, Daniel, Lentz, Steven R., Tommasi, Sara, Martens-Lobenhoffer, Jens, Suzuki-Yamamoto, Toshiko, Kimoto, Masumi, Rubets, Elena, Chau, Sarah, Chen, Yingjie, Hu, Xinli, Bernhardt, Nadine, Spieth, Peter M., Weiss, Norbert, Bornstein, Stefan R., Mukhopadhyay, Debabrata, Bode-Böger, Stefanie M., Maas, Renke, Wang, Ying, Macchiarulo, Antonio, Mangoni, Arduino A., Cellini, Barbara, Rodionov, Roman N.

“…Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cardiovascular disease by metabolising the risk factor asymmetric dimethylarginine (ADMA)…”
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Electrophysiological characterization of a Cav3.2 calcium channel missense variant associated with epilepsy and hearing loss by Stringer, Robin N, Cmarko, Leos, Zamponi, Gerald W, De Waard, Michel, Weiss, Norbert

“…Abstract T-type calcium channelopathies encompass a group of human disorders either caused or exacerbated by mutations in the genes encoding different T-type…”
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MicroRNA-138 regulates hypoxia-induced endothelial cell dysfunction by targeting S100A1 by Sen, Anagha, Ren, Shumei, Lerchenmüller, Carolin, Sun, Jianxin, Weiss, Norbert, Most, Patrick, Peppel, Karsten

“…The Ca(2+) sensor S100A1 is essential for proper endothelial cell (EC) nitric oxide (NO) synthase (eNOS) activation. S100A1 levels are greatly reduced in…”
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Control of depolarization-evoked presynaptic neurotransmitter release by Cav2.1 calcium channel: Old story, new insights by Weiss, Norbert

“…Commentary on: Research Paper Ca V 2.1 (P/Q channel) interaction with synaptic proteins is essential for depolarization-evoked release by Moshe Cohen-Kutner,…”
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T-tubule disorganization and defective excitation-contraction coupling in muscle fibers lacking myotubularin lipid phosphatase by Al-Qusairi, Lama, Weiss, Norbert, Toussaint, Anne, Berbey, Céline, Messaddeq, Nadia, Kretz, Christine, Sanoudou, Despina, Beggs, Alan H, Allard, Bruno, Mandel, Jean-Louis, Laporte, Jocelyn, Jacquemond, Vincent, Buj-Bello, Anna

“…Skeletal muscle contraction is triggered by the excitation-contraction (E-C) coupling machinery residing at the triad, a membrane structure formed by the…”
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Secretory carrier-associated membrane protein 2 (SCAMP2) regulates cell surface expression of T-type calcium channels by Cmarko, Leos, Stringer, Robin N, Jurkovicova-Tarabova, Bohumila, Vacik, Tomas, Lacinova, Lubica, Weiss, Norbert

“…Low-voltage-activated T-type Ca channels are key regulators of neuronal excitability both in the central and peripheral nervous systems. Therefore, their…”
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Screening an In-House Isoquinoline Alkaloids Library for New Blockers of Voltage-Gated Na+ Channels Using Voltage Sensor Fluorescent Probes: Hits and Biases by Coquerel, Quentin, Legendre, Claire, Frangieh, Jacinthe, Waard, Stephan, Montnach, Jérôme, Cmarko, Leos, Khoury, Joseph, Hassane, Charifat, Bréard, Dimitri, Siegler, Benjamin, Fajloun, Ziad, De Pomyers, Harold, Mabrouk, Kamel, Weiss, Norbert, Henrion, Daniel, Richomme, Pascal, Mattei, César, Waard, Michel, Le Ray, Anne-Marie, Legros, Christian

“…Voltage-gated Na+ (NaV) channels are significant therapeutic targets for the treatment of cardiac and neurological disorders, thus promoting the search for…”
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Endovascular Creation of an Arteriovenous Fistula (endoAVF) for Hemodialysis Access: First Results by Radosa, Christoph Georg, Radosa, Julia Caroline, Weiss, Norbert, Schmidt, Christine, Werth, Sebastian, Hofmockel, Thomas, Plodeck, Verena, Gatzweiler, Christian, Laniado, Michael, Hoffmann, Ralf-Thorsten

“…Introduction Surgical creation of a radiocephalic fistula is the gold standard of vascular access for hemodialysis. Recently, an endovascular approach for…”
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Overexpression of alanine-glyoxylate aminotransferase 2 protects from asymmetric dimethylarginine-induced endothelial dysfunction and aortic remodeling by Rodionov, Roman N., Jarzebska, Natalia, Burdin, Dmitrii, Todorov, Vladimir, Martens-Lobenhoffer, Jens, Hofmann, Anja, Kolouschek, Anne, Cordasic, Nada, Jacobi, Johannes, Rubets, Elena, Morawietz, Henning, O’Sullivan, John F., Markov, Alexander G., Bornstein, Stefan R., Hilgers, Karl, Maas, Renke, Pfluecke, Christian, Chen, YingJie, Bode-Böger, Stefanie M., Hugo, Christian P. M., Hohenstein, Bernd, Weiss, Norbert

“…Elevated plasma concentrations of asymmetric dimethylarginine (ADMA) are associated with an increased risk of mortality and adverse cardiovascular outcomes…”
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De novo SCN8A and inherited rare CACNA1H variants associated with severe developmental and epileptic encephalopathy by Stringer, Robin N, Jurkovicova-Tarabova, Bohumila, Souza, Ivana A, Ibrahim, Judy, Vacik, Tomas, Fathalla, Waseem Mahmoud, Hertecant, Jozef, Zamponi, Gerald W, Lacinova, Lubica, Weiss, Norbert

“…Developmental and epileptic encephalopathies (DEEs) are a group of severe epilepsies that are characterized by seizures and developmental delay. DEEs are…”
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