Search Results - "Weiss, Ethan J"

Hepatocyte-Specific Disruption of CD36 Attenuates Fatty Liver and Improves Insulin Sensitivity in HFD-Fed Mice by Wilson, Camella G, Tran, Jennifer L, Erion, Derek M, Vera, Nicholas B, Febbraio, Maria, Weiss, Ethan J

“…CD36/FAT (fatty acid translocase) is associated with human and murine nonalcoholic fatty liver disease, but it has been unclear whether it is simply a marker…”
Get full text

An evolutionary trade-off between host immunity and metabolism drives fatty liver in male mice by Nikkanen, Joni, Leong, Yew Ann, Krause, William C, Dermadi, Denis, Maschek, J Alan, Van Ry, Tyler, Cox, James E, Weiss, Ethan J, Gokcumen, Omer, Chawla, Ajay, Ingraham, Holly A

“…Adaptations to infectious and dietary pressures shape mammalian physiology and disease risk. How such adaptations affect sex-biased diseases remains…”
Get full text

4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor by Moldavski, Ofer, Zushin, Peter-James H., Berdan, Charles A., Van Eijkeren, Robert J., Jiang, Xuntian, Qian, Mingxing, Ory, Daniel S., Covey, Douglas F., Nomura, Daniel K., Stahl, Andreas, Weiss, Ethan J., Zoncu, Roberto

“…Oxysterols are oxidized derivatives of cholesterol that play regulatory roles in lipid biosynthesis and homeostasis. How oxysterol signaling coordinates…”
Get full text

Use of an mHealth Ketogenic Diet App Intervention and User Behaviors Associated With Weight Loss in Adults With Overweight or Obesity: Secondary Analysis of a Randomized Clinical Trial by Falkenhain, Kaja, Locke, Sean R, Lowe, Dylan A, Lee, Terry, Singer, Joel, Weiss, Ethan J, Little, Jonathan P

“…Low-carbohydrate ketogenic diets are a viable method to lose weight that have regained popularity in recent years. Technology in the form of mobile health…”
Get full text

Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity: The TREAT Randomized Clinical Trial by Lowe, Dylan A, Wu, Nancy, Rohdin-Bibby, Linnea, Moore, A Holliston, Kelly, Nisa, Liu, Yong En, Philip, Errol, Vittinghoff, Eric, Heymsfield, Steven B, Olgin, Jeffrey E, Shepherd, John A, Weiss, Ethan J

“…The efficacy and safety of time-restricted eating have not been explored in large randomized clinical trials. To determine the effect of 16:8-hour…”
Get more information

PAR3 is a cofactor for PAR4 activation by thrombin by Coughlin, Shaun R, Nakanishi-Matsui, Mayumi, Zheng, Yao-Wu, Sulciner, David J, Weiss, Ethan J, Ludeman, Matthew J

“…Identification of the mechanisms by which the coagulation protease thrombin activates platelets is critical for understanding haemostasis and thrombosis…”
Get full text

Protection against thrombosis in mice lacking PAR3 by Weiss, Ethan J., Hamilton, Justin R., Lease, Katy E., Coughlin, Shaun R.

“…The recent observation that knock-out of protease-activated receptor-4 (PAR4) ablates thrombin signaling in mouse platelets and protects against ferric…”
Get full text

Growth hormone receptor antagonism with pegvisomant in insulin resistant non-diabetic men: A phase II pilot study by Lee, Ada P, Mulligan, Kathleen, Schambelan, Morris, Murphy, Elizabeth J, Weiss, Ethan J

“…Growth hormone (GH) is known to affect insulin and glucose metabolism.  Blocking its effects in acromegalic patients improves diabetes and glucose metabolism…”
Get full text

Billy Idol by Weiss, Ethan J

“…Ruthie Weiss was born with white hair, but her parents did not consider the possibility of there being more to the story until they noticed that she was not…”
Get more information

A Polymorphism of a Platelet Glycoprotein Receptor as an Inherited Risk Factor for Coronary Thrombosis by Weiss, Ethan J, Weiss, James L, Bray, Paul F, Tayback, Matthew, Schulman, Steven P, Kickler, Thomas S, Becker, Lewis C, Gerstenblith, Gary, Goldschmidt-Clermont, Pascal J

“…Studies indicate that myocardial infarction and unstable angina result from the formation of a platelet aggregate at the site of a ruptured coronary…”
Get full text

Relationship of Fat Mass Ratio, a Biomarker for Lipodystrophy, With Cardiometabolic Traits by Agrawal, Saaket, Luan, Jian'an, Cummings, Beryl B, Weiss, Ethan J, Wareham, Nick J, Khera, Amit V

“…Familial partial lipodystrophy (FPLD) is a heterogenous group of syndromes associated with a high prevalence of cardiometabolic diseases. Prior work has…”
Get full text

Effect of carbohydrate-restricted dietary interventions on LDL particle size and number in adults in the context of weight loss or weight maintenance: a systematic review and meta-analysis by Falkenhain, Kaja, Roach, Lauren A, McCreary, Sara, McArthur, Eric, Weiss, Ethan J, Francois, Monique E, Little, Jonathan P

“…LDL particle size and number (LDL-P) are emerging lipid risk factors. Nonsystematic reviews have suggested that diets lower in carbohydrates and higher in fats…”
Get full text

Assessment of clinical measures of total and regional body composition from a commercial 3-dimensional optical body scanner by Bennett, Jonathan P., Liu, Yong En, Quon, Brandon K., Kelly, Nisa N., Wong, Michael C., Kennedy, Samantha F., Chow, Dominic C., Garber, Andrea K., Weiss, Ethan J., Heymsfield, Steven B., Shepherd, John A.

“…The accurate assessment of total body and regional body circumferences, volumes, and compositions are critical to monitor physical activity and dietary…”
Get full text

Keyto app and device versus WW app on weight loss and metabolic risk in adults with overweight or obesity: A randomized trial by Falkenhain, Kaja, Locke, Sean R., Lowe, Dylan A., Reitsma, Nicholas J., Lee, Terry, Singer, Joel, Weiss, Ethan J., Little, Jonathan P.

“…Objective The aim of this study was to determine whether a Mediterranean‐style, ketogenic diet mobile health application (app) with breath acetone biofeedback…”
Get full text

Three‐dimensional optical body shape and features improve prediction of metabolic disease risk in a diverse sample of adults by Bennett, Jonathan P., Liu, Yong En, Quon, Brandon K., Kelly, Nisa N., Leong, Lambert T., Wong, Michael C., Kennedy, Samantha F., Chow, Dominic C., Garber, Andrea K., Weiss, Ethan J., Heymsfield, Steven B., Shepherd, John A.

“…Objective This study examined whether body shape and composition obtained by three‐dimensional optical (3DO) scanning improved the prediction of metabolic…”
Get full text

Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2 by Sos, Brandon C, Harris, Charles, Nordstrom, Sarah M, Tran, Jennifer L, Balázs, Mercedesz, Caplazi, Patrick, Febbraio, Maria, Applegate, Milana A B, Wagner, Kay-Uwe, Weiss, Ethan J

“…Non-alcoholic fatty liver disease is associated with multiple comorbid conditions, including diabetes, obesity, infection, and malnutrition. Mice with…”
Get full text

Disruption of JAK2 in Adipocytes Impairs Lipolysis and Improves Fatty Liver in Mice With Elevated GH by Nordstrom, Sarah M, Tran, Jennifer L, Sos, Brandon C, Wagner, Kay-Uwe, Weiss, Ethan J

“…Nonalcoholic fatty liver disease (NAFLD) is considered the hepatic expression of the metabolic syndrome, and its prevalence is increasing. The factors that…”
Get full text

Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling by Corbit, Kevin C, Camporez, João Paulo G, Edmunds, Lia R, Tran, Jennifer L, Vera, Nicholas B, Erion, Derek M, Deo, Rahul C, Perry, Rachel J, Shulman, Gerald I, Jurczak, Michael J, Weiss, Ethan J

“…Disruption of hepatocyte growth hormone (GH) signaling through disruption of (JAK2L) leads to fatty liver. Previously, we demonstrated that development of…”
Get full text

Role of thrombin signalling in platelets in haemostasis and thrombosis by Coughlin, Shaun R, Sambrano, Gilberto R, Weiss, Ethan J, Zheng, Yao-Wu, Huang, Wei

“…Platelets are critical in haemostasis and in arterial thrombosis, which causes heart attacks and other events triggered by abnormal clotting. The coagulation…”
Get full text

Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns by Wong, Joshua H, Dukes, Jonathan, Levy, Robert E, Sos, Brandon, Mason, Sara E, Fong, Tina S, Weiss, Ethan J

“…Sex differences in thrombosis are well described, but their underlying mechanism(s) are not completely understood. Coagulation proteins are synthesized in the…”
Get full text