Search Results - "Weiss, Celine S"
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Beneficial Effects of Mammalian Target of Rapamycin Inhibition on Left Ventricular Remodeling After Myocardial Infarction
Published in Journal of the American College of Cardiology (15-12-2009)“…Objectives The extent of adverse myocardial remodeling contributes essentially to the prognosis after myocardial infarction (MI). In this study we investigated…”
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2
Wnt Signaling Is Critical for Maladaptive Cardiac Hypertrophy and Accelerates Myocardial Remodeling
Published in Hypertension (Dallas, Tex. 1979) (01-04-2010)“…The evolutionary conserved Wnt signaling pathway regulates cardiogenesis. However, members of the Wnt pathway are also expressed in the adult heart. Although…”
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3
Myocardial Left Ventricular Dysfunction in Patients with Systemic Lupus Erythematosus: New Insights from Tissue Doppler and Strain Imaging
Published in Journal of rheumatology (01-01-2010)“…Objective. Systemic lupus erythematosus (SLE) is associated with high cardiovascular morbidity and mortality. Cardiovascular involvement is frequently…”
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4
Cardiac Effects of Attenuating Gsα - Dependent Signaling
Published in PloS one (01-01-2016)“…Inhibition of β-adrenergic signalling plays a key role in treatment of heart failure. Gsα is essential for β-adrenergic signal transduction. In order to reduce…”
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5
DYRK2 negatively regulates cardiomyocyte growth by mediating repressor function of GSK-3β on eIF2Bε
Published in PloS one (04-09-2013)“…A prerequisite of hypertrophic response of the myocardium is an increase in protein synthesis. A central regulator of translation initiation is Eukaryotic…”
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6
High-sensitive Troponin T increase after exercise in patients with pulmonary arterial hypertension
Published in BMC pulmonary medicine (29-04-2013)“…The current study aimed to investigate the release of myocardial high-sensitive Troponin T (hsTnT) in patients with pulmonary arterial hypertension (PAH) in…”
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Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of β-catenin and elicits distinct features of cardiomyocyte hypertrophy
Published in FEBS letters (04-01-2010)“…Cardiac myocyte growth is under differential control of mammalian target of rapamycin (mTOR) and glycogen-synthase-kinase-3 β (GSK3 β). Whereas active GSK3 β…”
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8
Cardiac Effects of Attenuating Gs[alpha] - Dependent Signaling
Published in PloS one (26-01-2016)“…Aims Inhibition of [beta]-adrenergic signalling plays a key role in treatment of heart failure. Gs[alpha] is essential for [beta]-adrenergic signal…”
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9
DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3[beta] on eIF2B[epsilon]
Published in PloS one (04-09-2013)“…Background A prerequisite of hypertrophic response of the myocardium is an increase in protein synthesis. A central regulator of translation initiation is…”
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10
Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of b-catenin and elicits distinct features of cardiomyocyte hypertrophy
Published in FEBS letters (04-01-2010)“…Cardiac myocyte growth is under differential control of mammalian target of rapamycin (mTOR) and glycogen-synthase-kinase-3b (GSK3b). Whereas active GSK3b…”
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11
Activation of PPARγ by pioglitazone does not attenuate left ventricular hypertrophy following aortic banding in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2010)“…Sustained left ventricular hypertrophy (LVH) accelerates cardiac dysfunction and heart failure. Previous reports have suggested that activation of the…”
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12
Activation of PPARgamma by pioglitazone does not attenuate left ventricular hypertrophy following aortic banding in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-04-2010)“…Sustained left ventricular hypertrophy (LVH) accelerates cardiac dysfunction and heart failure. Previous reports have suggested that activation of the…”
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