Search Results - "Weiss, Alison"

Intestinal organoids model human responses to infection by commensal and Shiga toxin producing Escherichia coli by Karve, Sayali S, Pradhan, Suman, Ward, Doyle V, Weiss, Alison A

“…Infection with Shiga toxin (Stx) producing Escherichia coli O157:H7 can cause the potentially fatal complication hemolytic uremic syndrome, and currently only…”
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Needle in a haystack: localising the long-term neuronal changes from early-life exposure to general anaesthesia by Kim, Greena, Weiss, Alison R, Raper, Jessica

“…Narrowing down the histopathological changes in the brain after early-life exposure to general anaesthesia has presented a consistent challenge for preclinical…”
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Intra-striatal AAV2.retro administration leads to extensive retrograde transport in the rhesus macaque brain: implications for disease modeling and therapeutic development by Weiss, Alison R., Liguore, William A., Domire, Jacqueline S., Button, Dana, McBride, Jodi L.

“…Recently, AAV2.retro, a new capsid variant capable of efficient retrograde transport in brain, was generated in mice using a directed evolution approach…”
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Glycolipid binding preferences of Shiga toxin variants by Karve, Sayali S, Weiss, Alison A

“…The major virulence factor of Shiga toxin producing E. coli, is Shiga toxin (Stx), an AB5 toxin that consists of a ribosomal RNA-cleaving A-subunit surrounded…”
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Shiga Toxin Subtypes Display Dramatic Differences in Potency by Fuller, Cynthia A, Pellino, Christine A, Flagler, Michael J, Strasser, Jane E, Weiss, Alison A

“…Purified Shiga toxin (Stx) alone is capable of producing systemic complications, including hemolytic-uremic syndrome (HUS), in animal models of disease. Stx…”
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Colorimetric viral detection based on sialic acid stabilized gold nanoparticles by LEE, Changwon, GASTON, Marsha A, WEISS, Alison A, PENG ZHANG

“…Sialic acid reduced and stabilized gold nanoparticles (d=20.1±1.8 nm) were synthesized by a simple one-pot, green method without chemically modifying sialic…”
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Shiga toxin binding to glycolipids and glycans by Gallegos, Karen M, Conrady, Deborah G, Karve, Sayali S, Gunasekera, Thusitha S, Herr, Andrew B, Weiss, Alison A

“…Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding…”
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Reduced D2/D3 Receptor Binding and Glucose Metabolism in a Macaque Model of Huntington's Disease by Weiss, Alison R., Bertoglio, Daniele, Liguore, William A., Brandon, Kristin, Templon, John, Link, Jeanne, McBride, Jodi L.

“…Background Dopamine system dysfunction and altered glucose metabolism are implicated in Huntington's disease (HD), a neurological disease caused by mutant…”
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Probiotic Properties of Escherichia coli Nissle in Human Intestinal Organoids by Pradhan, Suman, Weiss, Alison Ann

“…strain Nissle has been used as a probiotic and therapeutic agent for over a century. Reports suggest that Nissle protects mice from enterohemorrhagic (EHEC)…”
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Electroosmotic flow driven microfluidic device for bacteria isolation using magnetic microbeads by Miller, Samuel, Weiss, Alison A., Heineman, William R., Banerjee, Rupak K.

“…The presence of bacterial pathogens in water can lead to severe complications such as infection and food poisoning. This research proposes a point-of-care…”
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Microglia, inflammation and gut microbiota responses in a progressive monkey model of Parkinson's disease: A case series by Joers, Valerie, Masilamoni, Gunasingh, Kempf, Doty, Weiss, Alison R., Rotterman, Travis M., Murray, Benjamin, Yalcin-Cakmakli, Gul, Voll, Ronald J., Goodman, Mark M., Howell, Leonard, Bachevalier, Jocelyne, Green, Stefan J., Naqib, Ankur, Shaikh, Maliha, Engen, Phillip A., Keshavarzian, Ali, Barnum, Christopher J., Nye, Jonathon A., Smith, Yoland, Tansey, Malú G.

“…Inflammation has been linked to the development of nonmotor symptoms in Parkinson's disease (PD), which greatly impact patients' quality of life and can often…”
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Reduced D 2 /D 3 Receptor Binding and Glucose Metabolism in a Macaque Model of Huntington's Disease by Weiss, Alison R, Bertoglio, Daniele, Liguore, William A, Brandon, Kristin, Templon, John, Link, Jeanne, McBride, Jodi L

“…Dopamine system dysfunction and altered glucose metabolism are implicated in Huntington's disease (HD), a neurological disease caused by mutant huntingtin…”
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Object and spatial memory after neonatal perirhinal lesions in monkeys by Weiss, Alison R., Bachevalier, Jocelyne

“…•Object and location memory was assessed in monkeys with neonatal perirhinal lesions.•Recognition of objects after delays longer than 30s was impaired.•No…”
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Human Pluripotent Stem Cell-Derived Intestinal Organoid Model for the Study of Human Responses to Infection Shiga Toxin Producing Escherichia Coli -Induced Pathogenesis by Pradhan, Suman, Karve, Sayali, Weiss, Alison A

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Selective vulnerability of layer 5a corticostriatal neurons in Huntington's disease by Pressl, Christina, Mätlik, Kert, Kus, Laura, Darnell, Paul, Luo, Ji-Dung, Paul, Matthew R, Weiss, Alison R, Liguore, William, Carroll, Thomas S, Davis, David A, McBride, Jodi, Heintz, Nathaniel

“…The properties of the cell types that are selectively vulnerable in Huntington's disease (HD) cortex, the nature of somatic CAG expansions of mHTT in these…”
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Psychoactive and other ceremonial plants from a 2,000-year-old Maya ritual deposit at Yaxnohcah, Mexico by Lentz, David L, Hamilton, Trinity L, Meyers, Stephanie A, Dunning, Nicholas P, Reese-Taylor, Kathryn, Hernández, Armando Anaya, Walker, Debra S, Tepe, Eric J, Esquivel, Atasta Flores, Weiss, Alison A

“…For millennia, healing and psychoactive plants have been part of the medicinal and ceremonial fabric of elaborate rituals and everyday religious practices…”
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Environmental DNA reveals arboreal cityscapes at the Ancient Maya Center of Tikal by Lentz, David L., Hamilton, Trinity L., Dunning, Nicholas P., Tepe, Eric J., Scarborough, Vernon L., Meyers, Stephanie A., Grazioso, Liwy, Weiss, Alison A.

“…Tikal, a major city of the ancient Maya world, has been the focus of archaeological research for over a century, yet the interactions between the Maya and the…”
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The macaque brain ONPRC18 template with combined gray and white matter labelmap for multimodal neuroimaging studies of Nonhuman Primates by Weiss, Alison R., Liu, Zheng, Wang, Xiaojie, Liguore, William A., Kroenke, Christopher D., McBride, Jodi L.

“…Macaques are the most common nonhuman primate (NHP) species used in neuroscience research. With the advancement of many neuroimaging techniques, new studies…”
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A novel rhesus macaque model of Huntington's disease recapitulates key neuropathological changes along with motor and cognitive decline by Weiss, Alison R, Liguore, William A, Brandon, Kristin, Wang, Xiaojie, Liu, Zheng, Domire, Jacqueline S, Button, Dana, Srinivasan, Sathya, Kroenke, Christopher D, McBride, Jodi L

“…We created a new nonhuman primate model of the genetic neurodegenerative disorder Huntington's disease (HD) by injecting a mixture of recombinant…”
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A Zinc-Dependent Adhesion Module Is Responsible for Intercellular Adhesion in Staphylococcal Biofilms by Conrady, Deborah G., Brescia, Cristin C., Horii, Katsunori, Weiss, Alison A., Hassett, J., Herr, Andrew B.

“…Hospital-acquired bacterial infections are an increasingly important cause of morbidity and mortality worldwide. Staphylococcal species are responsible for the…”
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