Search Results - "Weisinger, Richard S"

The Role of Eicosanoids in the Brain by Tassoni, Daniella, Kaur, Gunveen, Weisinger, Richard S, Sinclair, Andrew J

“…The brain contains two main polyunsaturated fatty acids (PUFA), arachidonic acid (AA) and docosahexaenoic acid (DHA). These PUFA are located almost exclusively…”
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Impaired Fluid Intake, but Not Sodium Appetite, in Aged Rats Is Mediated by the Cyclooxygenase-Prostaglandin E2 Pathway by Begg, Denovan P., Sinclair, Andrew J., Weisinger, Richard S.

“…Aging results in decreased fluid intake following dehydration and other dipsogenic stimuli; similar reductions in sodium intake have also been observed with…”
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Mice lacking angiotensin-converting enzyme have increased energy expenditure, with reduced fat mass and improved glucose clearance by Jayasooriya, Anura P, Mathai, Michael L, Walker, Lesley L, Begg, Denovan P, Denton, Derek A, Cameron-Smith, David, Egan, Gary F, McKinley, Michael J, Rodger, Paula D, Sinclair, Andrew J, Wark, John D, Weisinger, Harrison S, Jois, Mark, Weisinger, Richard S

“…In addition to its role in the storage of fat, adipose tissue acts as an endocrine organ, and it contains a functional renin-angiotensin system (RAS)…”
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Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet by Chen, Nora, Bezzina, Rebecca, Hinch, Edward, Lewandowski, Paul A, Cameron-Smith, David, Mathai, Michael L, Jois, Markandeya, Sinclair, Andrew J, Begg, Denovan P, Wark, John D, Weisinger, Harrison S, Weisinger, Richard S

“…Abstract The mechanisms of how tea and epigallocatechin-3-gallate (EGCG) lower body fat are not completely understood. This study investigated long-term…”
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Omega 3 Fatty Acids and the Brain: Review of Studies in Depression by Sinclair, Andrew J, Begg, Denovan, Mathai, Michael, Weisinger, Richard S

“…The brain is a lipid-rich organ containing mostly complex polar phospholipids, sphingolipids, gangliosides and cholesterol. These lipids are involved in the…”
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Effects of Dietary Omega-3 Polyunsaturated Fatty Acids on Brain Gene Expression by Kitajka, Klára, Sinclair, Andrew J., Weisinger, Richard S., Weisinger, Harrison S., Mathai, Michael, Jayasooriya, Anura P., Halver, John E., Puskás, László G.

“…Polyunsaturated fatty acids (PUFA) are essential structural components of the central nervous system. Their role in controlling learning and memory has been…”
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Angiotensin converting enzyme inhibition lowers body weight and improves glucose tolerance in C57BL/6J mice maintained on a high fat diet by Weisinger, Richard S, Stanley, Tracy K, Begg, Denovan P, Weisinger, Harrison S, Spark, Kylie J, Jois, Markandeya

“…Abstract The renin–angiotensin system (RAS) is functional within adipose tissue and angiotensin II, the active component of RAS, has been implicated in adipose…”
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Inhibition of the Renin-Angiotensin System Reduces Gene Expression of Inflammatory Mediators in Adipose Tissue Independent of Energy Balance by Mitchell, Caitlin S, Premaratna, Shirmila D, Bennett, Garth, Lambrou, Maria, Stahl, Lauren A, Jois, Markandeya, Barber, Elizabeth, Antoniadis, Christopher P, Woods, Stephen C, Cameron-Smith, David, Weisinger, Richard S, Begg, Denovan P

“…Obesity is a growing health problem worldwide. The renin-angiotensin system (RAS) is present in adipose tissue, and evidence suggests that it is involved in…”
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Polyphenol Rich Sugarcane Extract Reduces Body Weight in C57/BL6J Mice Fed a High Fat, High Carbohydrate Diet by Flavel, Matthew, Ellis, Timothy P., Stahl, Lauren, Begg, Denovan, Smythe, Jason, Ilag, Leodevico L., Weisinger, Richard S., Kitchen, Barry, Jois, Markandeya

“…Background: Energy-dense diets have been implicated as a driving force in the global obesity crisis. Sucrose derived from sugar cane (Saccharum officinarum) is…”
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Hypothalamic gene expression in ω-3 PUFA-deficient male rats before, and following, development of hypertension by Begg, Denovan P, Puskás, László G, Kitajka, Klara, Ménesi, Dalma, Allen, Andrew M, Li, Duo, Mathai, Michael L, Shi, Jian R, Sinclair, Andrew J, Weisinger, Richard S

“…Dietary deficiency of ω-3 fatty acids (ω-3 DEF) produces hypertension in later life. This study examined the effect of ω-3 DEF on blood pressure and…”
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Hypertension induced by ω-3 polyunsaturated fatty acid deficiency is alleviated by α-linolenic acid regardless of dietary source by Begg, Denovan P, Sinclair, Andrew J, Stahl, Lauren A, Premaratna, Shirmila D, Hafandi, Ahmad, Jois, Mark, Weisinger, Richard S

“…Omega-3 polyunsaturated fatty acid deficiency, particularly during the prenatal period, can cause hypertension in later life. This study examined the effect of…”
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Angiotensin converting enzyme inhibition from birth reduces body weight and body fat in Sprague–Dawley rats by Weisinger, Harrison S, Begg, Denovan P, Egan, Gary F, Jayasooriya, Anura P, Lie, Fanny, Mathai, Michael L, Sinclair, Andrew J, Wark, John D, Weisinger, Richard S

“…Abstract In vitro studies have demonstrated that angiotensin II (ANG II) induces adipocyte hyperplasia and hypertrophy. The aim of the present study was to…”
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Perinatal omega-3 fatty acid deficiency affects blood pressure later in life by Weisinger, Harrison S, Armitage, James A, Sinclair, Andrew J, Vingrys, Algis J, Burns, Peta L, Weisinger, Richard S

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Cardiovascular actions of CRH and urocortin: an update by Parkes, David G, Weisinger, Richard S, May, Clive N

“…Urocortin is a potent regulator of cardiac function, with actions that are prolonged in experimental animals. These changes are mediated via binding to CRH…”
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Perinatal omega-3 polyunsaturated fatty acid supply modifies brain zinc homeostasis during adulthood by Jayasooriya, A.P, Ackland, M.L, Mathai, M.L, Sinclair, A.J, Weisinger, H.S, Weisinger, R.S, Halver, J.E, Kitajka, K, Puskas, L.G

“…Dietary ω-3 polyunsaturated fatty acid (PUFA) influences the expression of a number of genes in the brain. Zinc transporter (ZnT) 3 has been identified as a…”
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Impaired Fluid Intake, but Not Sodium Appetite, in Aged Rats Is Mediated by the Cyclooxygenase-Prostaglandin E 2 Pathway by Begg, Denovan P, Sinclair, Andrew J, Weisinger, Richard S

“…Aging results in decreased fluid intake following dehydration and other dipsogenic stimuli; similar reductions in sodium intake have also been observed with…”
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Calorie restricted rats do not increase metabolic rate post-LPS, but do seek out warmer ambient temperatures to behaviourally induce a fever by MacDonald, Leah, Begg, Denovan, Weisinger, Richard S, Kent, Stephen

“…Abstract Due to previous work where we have demonstrated attenuated febrile responses post-lipopolysaccharide (LPS) in calorie restricted (CR) rodents we aimed…”
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The Problem of Obesity: Is There a Role for Antagonists of the Renin-Angiotensin System? by Weisinger, Richard S, Begg, Denovan P, Chen, Nora, Jois, Mark, Mathai, Michael L, Sinclair, Andrew J

“…Obesity is a major health problem worldwide; it is associated with more than 30 medical conditions and is a leading cause of unnecessary deaths. Adipose tissue…”
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Retinal sensitivity loss in third-generation n-3 PUFA-deficient rats by Weisinger, Harrison S, Armitage, James A, Jeffrey, Brett G, Mitchell, Drake C, Moriguchi, Toru, Sinclair, Andrew J, Weisinger, Richard S, Salem, Norman, Jr

“…A previous study conducted in guinea pigs suggested that ingestion of diets high in EPA and DHA may result in suboptimal retinal function. The aim of the…”
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Thirst deficits in aged rats are reversed by dietary omega-3 fatty acid supplementation by Begg, Denovan P, Sinclair, Andrew J, Weisinger, Richard S

“…Abstract During heat waves many elderly individuals die as a consequence of dehydration. This is partially due to deficits in mechanisms controlling thirst…”
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