Search Results - "Weisheit, Simona"
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Sonic hedgehog-dependent activation of adventitial fibroblasts promotes neointima formation
Published in Cardiovascular research (01-11-2017)“…Adventitial cells have been suggested to contribute to neointima formation, but the functional relevance and the responsible signalling pathways are largely…”
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2
Allosteric modulation by protein kinase Cε leads to modified responses of EGF receptor towards tyrosine kinase inhibitors
Published in Cellular signalling (01-02-2012)“…Recently, we described a novel function of over-expressed protein kinase Cε (PKCε) as a negative allosteric modulator of EGFR signalling in several head and…”
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3
Activation by tyrosine phosphorylation as a prerequisite for protein kinase Cζ to mediate epidermal growth factor receptor signaling to ERK
Published in Molecular cancer research (01-05-2010)“…The atypical protein kinase Czeta (PKCzeta) was recently shown to mediate epidermal growth factor (EGF)-induced activation of extracellular signal-regulated…”
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4
Cleaved high-molecular-weight kininogen inhibits neointima formation following vascular injury
Published in Thrombosis and haemostasis (31-08-2015)“…Cleaved high-molecular-weight kininogen (HKa) or its peptide domain 5 (D5) alone exert anti-adhesive properties in vitro related to impeding integrin-mediated…”
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5
A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer
Published in Oncotarget (01-01-2012)“…Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common malignant neoplasm and more than 50% of patients succumb to this disease. HNSCCs are…”
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PKCε acts as negative allosteric modulator of EGF receptor signalling
Published in Cellular signalling (01-02-2011)“…Protein kinase C ε (PKCε) is a transforming oncogene and plays a pivotal role in numerous cellular processes including proliferation, invasion and…”
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