Search Results - "Weisell, Janne"

SPECT/CT imaging of radiolabeled cubosomes and hexosomes for potential theranostic applications by Nilsson, Christa, Barrios-Lopez, Brianda, Kallinen, Annukka, Laurinmäki, Pasi, Butcher, Sarah J, Raki, Mari, Weisell, Janne, Bergström, Kim, Larsen, Susan Weng, Østergaard, Jesper, Larsen, Claus, Urtti, Arto, Airaksinen, Anu J, Yaghmur, Anan

“…Abstract We have developed a highly efficient method for the radiolabeling of phytantriol (PHYT)/oleic acid (OA)-based hexosomes based on the surface chelation…”
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Human Urine and Wood Ash as Plant Nutrients for Red Beet (Beta vulgaris) Cultivation: Impacts on Yield Quality by Pradhan, Surendra K, Holopainen, Jarmo K, Weisell, Janne, Heinonen-Tanski, Helvi

“…The objective of this study was to evaluate the effect of human urine and wood ash fertilization on the yield and quality of red beet by measuring the…”
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Straightforward carbamoylation of nucleophilic compounds employing organic azides, phosphines, and aqueous trialkylammonium hydrogen carbonate by Yagodkin, Andrey, Löschcke, Kerstin, Weisell, Janne, Azhayev, Alex

“…In the presence of aqueous trialkylammonium hydrogen carbonate, the Staudinger reaction leads to the intermediate formation of the corresponding isocyanate,…”
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Two strategies for the synthesis of the biologically important ATP analogue ApppI, at a multi-milligram scale by Weisell, Janne, Vepsäläinen, Jouko, Turhanen, Petri A

“…Two strategies for the synthesis of the ATP (adenosine triphosphate) analogue ApppI [1-adenosin-5'-yl 3-(3-methylbut-3-enyl)triphosphoric acid diester] (1) are…”
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Cost-effective FTIR and 1H NMR spectrometry used to screen valuable molecules extracted from selected West African trees by a sustainable biochar process by Salami, Ayobami, Vilppo, Teemu, Pitkänen, Sari, Weisell, Janne, Raninen, Kaisa, Vepsäläinen, Jouko, Lappalainen, Reijo

“…This study focused on wood extractives by a slow pyrolysis thermal extraction technique and screening of potentially valuable compounds from three African…”
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Charge deficient analogues of the natural polyamines by Weisell, Janne, Hyvönen, Mervi T, Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A, Khomutov, Alex R

“…Mitochondrial dysfunction, either inherited or acquired, is associated with several diseases in humans. Depending on the cell type and location, cells are…”
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Replacement of the Disulfide Bridge in a KLK3-Stimulating Peptide Using Orthogonally Protected Building Blocks by Meinander, Kristian, Pakkala, Miikka, Weisell, Janne, Stenman, Ulf-Håkan, Koistinen, Hannu, Närvänen, Ale, Wallén, Erik A. A

“…Peptide “B-2”, which is one of the most potent kallikrein-related peptidase 3 (KLK3)-stimulating compounds, consists of 12 amino acids and is cyclized by a…”
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Preparation of mixed trialkyl alkylcarbonate derivatives of etidronic acid via an unusual route by Turhanen, Petri A, Weisell, Janne, Vepsäläinen, Jouko J

“…A method to prepare four (3a-d) trialkyl alkylcarbonate esters of etidronate from P,P'-dimethyl etidronate and alkyl chloroformate was developed by utilizing…”
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Synthesis of novel bisphosphonate polyamine conjugates and their affinity to hydroxyapatite by Sankala, Elina, Weisell, Janne M., Huhtala, Tuulia, Närvänen, Ale T.O., Vepsäläinen, Jouko J.

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Structural Requirements for Bisphosphonate Binding on Hydroxyapatite: NMR Study of Bisphosphonate Partial Esters by Puljula, Elina, Turhanen, Petri, Vepsäläinen, Jouko, Monteil, Maelle, Lecouvey, Marc, Weisell, Janne

“…Eighteen different bisphosphonates, including four clinically used bisphosphonate acids and their phosphoesters, were studied to evaluate how the…”
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Stapled truncated orexin peptides as orexin receptor agonists by Karhu, Lasse, Weisell, Janne, Turunen, Pauli M., Leino, Teppo O., Pätsi, Henri, Xhaard, Henri, Kukkonen, Jyrki P., Wallén, Erik A.A.

“…•Peptide stapling of the neuropeptide orexin‐A15–33 lowers the potency significantly.•The peptide C-terminus is crucial for activity, and modifications were…”
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Novel target for peptide-based imaging and treatment of brain tumors by Hyvönen, Maija, Enbäck, Juulia, Huhtala, Tuulia, Lammi, Johanna, Sihto, Harri, Weisell, Janne, Joensuu, Heikki, Rosenthal-Aizman, Katri, El-Andaloussi, Samir, Langel, Ulo, Närvänen, Ale, Bergers, Gabriele, Laakkonen, Pirjo

“…Malignant gliomas are associated with high mortality due to infiltrative growth, recurrence, and malignant progression. Even with the most efficient therapy…”
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Triethylenetetramine modulates polyamine and energy metabolism and inhibits cancer cell proliferation by Hyvönen, Mervi T, Ucal, Sebahat, Pasanen, Markku, Peräniemi, Sirpa, Weisell, Janne, Khomutov, Maxim, Khomutov, Alex R, Vepsäläinen, Jouko, Alhonen, Leena, Keinänen, Tuomo A

“…Polyamine metabolism is an attractive anticancer drug target, since polyamines are absolutely required for cellular proliferation, and increased levels of…”
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Tautomeric populations of the charged species of 1,12-diamino-3,6,9-triazadodecane (SpmTrien) studied with computer simulations and cluster expansions: TAUTOMERIC POPULATIONS OF THE CHARGED SPECIES OF 1,12-DIAMINO-3,6,9-TRIAZADODECANE (SPMTRIEN) by Weisell, Janne, Vepsäläinen, Jouko, Peräkylä, Mikael

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Tautomeric populations of the charged species of 1,12-diamino-3,6,9-triazadodecane (SpmTrien) studied with computer simulations and cluster expansions by Weisell, Janne, Vepsäläinen, Jouko, Peräkylä, Mikael

“…Correct net charge and protonation pattern in the polyamine backbone is one of the major factors that define the interactions of this class of compounds…”
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706. Consistent Viral Vector Manufacturing for Phase III Using iCELLis 500 Fixed-Bed Technology by Karhinen, Minna, Nurminen, Elisa M., Valonen, Piia, Rautsi, Outi, Huusko, Vesa, Heikkilä, Kati, Weisell, Janne, Muller, Achim, Lesch, Hanna P., Närvänen, Outi, Hassinen, Minna M., Pollen, Minna, Parrish, Steve, Shaw, Robert, Parker, Nigel R., Ylä-Herttuala, Seppo

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Acetylated derivatives of C-methylated analogues of spermidine: synthesis and interaction with N1-acetylpolyamine oxidase by Khomutov, Maxim A., Hyvönen, Mervi T., Simonian, Alina R., Weisell, Janne, Vepsäläinen, Jouko, Alhonen, Leena, Kochetkov, Sergey N., Keinänen, Tuomo A., Khomutov, Alex R.

“…[Display omitted] The title compounds were prepared in high overall yields from properly protected (Boc, Cbz) 2- , 3- or 8-methyl-4-azaoctane-1,8-diamines…”
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Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine- N 1 -Acetyltransferase and Thialysine Acetyltransferase by Hyvönen, Mervi T., Weisell, Janne, Khomutov, Alex R., Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A.

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Metabolism of Triethylenetetramine and 1,12-Diamino-3,6,9-Triazadodecane by the Spermidine/Spermine-N super(1)-Acetyltransferase and Thialysine Acetyltransferase by Hyvonen, Mervi T, Weisell, Janne, Khomutov, Alex R, Alhonen, Leena, Vepsalainen, Jouko, Keinanen, Tuomo A

“…Triethylenetetramine (TETA; Syprine; Merck Rahway, NJ), a drug for Wilson's disease, is a copper chelator and a charge-deficient analog of polyamine…”
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Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A by Hyvönen, Mervi T, Koponen, Taina, Weisell, Janne, Pietilä, Marko, Khomutov, Alex R, Vepsäläinen, Jouko, Alhonen, Leena, Keinänen, Tuomo A

“…We have shown previously that the polyamine spermidine is indispensable for differentiation of 3T3-L1 preadipocytes. In the present study, we examined the…”
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