Search Results - "Weisell, J."

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  1. 1

    Novel hydroxylamine-containing analogues of 1-guanidino-7-aminoheptane (GC7), an effective inhibitor of deoxyhypusine synthase by Khomutov, M. A., Simonian, A. R., Weisell, J., Vepsalainen, J., Kochetkov, S. N., Khomutov, A. R.

    Published in Russian journal of bioorganic chemistry (01-07-2016)
    “…Earlier unknown hydroxylamine-containing analogues of 1-guanidino-7-aminohepane (GC7) containing the free aminooxy group (1-aminooxy-6-guanidinohexane),…”
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    Journal Article
  2. 2

    Hydroxylamine derivatives for regulation of spermine and spermidine metabolism by Khomutov, M. A., Weisell, J., Hyvönen, M., Keinänen, T. A., Vepsäläinen, J., Alhonen, L., Khomutov, A. R., Kochetkov, S. N.

    Published in Biochemistry (Moscow) (01-12-2013)
    “…The biogenic polyamines spermine, spermidine, and their precursor putrescine are present in micro-to-millimolar concentrations in all cell types and are…”
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    Novel target for peptide-based imaging and treatment of brain tumors by Hyvönen, Maija, Enbäck, Juulia, Huhtala, Tuulia, Lammi, Johanna, Sihto, Harri, Weisell, Janne, Joensuu, Heikki, Rosenthal-Aizman, Katri, El-Andaloussi, Samir, Langel, Ulo, Närvänen, Ale, Bergers, Gabriele, Laakkonen, Pirjo

    Published in Molecular cancer therapeutics (01-04-2014)
    “…Malignant gliomas are associated with high mortality due to infiltrative growth, recurrence, and malignant progression. Even with the most efficient therapy…”
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  7. 7

    Spermidine promotes adipogenesis of 3T3-L1 cells by preventing interaction of ANP32 with HuR and PP2A by Hyvönen, Mervi T, Koponen, Taina, Weisell, Janne, Pietilä, Marko, Khomutov, Alex R, Vepsäläinen, Jouko, Alhonen, Leena, Keinänen, Tuomo A

    Published in Biochemical journal (01-08-2013)
    “…We have shown previously that the polyamine spermidine is indispensable for differentiation of 3T3-L1 preadipocytes. In the present study, we examined the…”
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    Charge deficient analogues of the natural polyamines by Weisell, Janne, Hyvönen, Mervi T, Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A, Khomutov, Alex R

    Published in Current pharmaceutical design (01-01-2014)
    “…Mitochondrial dysfunction, either inherited or acquired, is associated with several diseases in humans. Depending on the cell type and location, cells are…”
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  10. 10

    Enantioselective synthesis of (R)- and (S)-3-methylspermidines by Khomutov, M. A., Keinanen, T. A., Hyvonen, M. T., Weisell, J., Vepsalainen, J., Alhonen, L., Kochetkov, S. N., Khomutov, A. R.

    Published in Russian journal of bioorganic chemistry (01-09-2015)
    “…Earlier unknown enantiomerically pure ( R )- and ( S )-1,8-diamino-3-methyl-4-azaoctane’s (3-MeSpd’s) were synthesized within 11 steps with high overall yields…”
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  11. 11

    Enantioselective Synthesis of (R)- and (S)-3-Methylspermidines by Khomutov, M A, Keinanen, T A, Hyvonen, M T, Weisell, J, Vepsalainen, J, Alhonen, L, Kochetkov, S N, Khomutov, A R

    Published in Bioorganicheskaia khimiia (01-09-2015)
    “…Earlier unknown enantiomerically pure (R)- and (S)-1,8-diamino-3-methyl-4-azaoctane's (3-MeSpd's) were synthesized with high overall yields and optical purity…”
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    Journal Article