Search Results - "Weir, Marion E."

NEDD4 family ubiquitin ligases associate with LCMV Z's PPXY domain and are required for virus budding, but not via direct ubiquitination of Z by Ziegler, Christopher M, Dang, Loan, Eisenhauer, Philip, Kelly, Jamie A, King, Benjamin R, Klaus, Joseph P, Manuelyan, Inessa, Mattice, Ethan B, Shirley, David J, Weir, Marion E, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Viral late domains are used by many viruses to recruit the cellular endosomal sorting complex required for transport (ESCRT) to mediate membrane scission…”
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The Lymphocytic Choriomeningitis Virus Matrix Protein PPXY Late Domain Drives the Production of Defective Interfering Particles by Ziegler, Christopher M, Eisenhauer, Philip, Bruce, Emily A, Weir, Marion E, King, Benjamin R, Klaus, Joseph P, Krementsov, Dimitry N, Shirley, David J, Ballif, Bryan A, Botten, Jason

“…Arenaviruses cause severe diseases in humans but establish asymptomatic, lifelong infections in rodent reservoirs. Persistently-infected rodents harbor high…”
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A novel phosphoserine motif in the LCMV matrix protein Z regulates the release of infectious virus and defective interfering particles by Ziegler, Christopher M, Eisenhauer, Philip, Bruce, Emily A, Beganovic, Vedran, King, Benjamin R, Weir, Marion E, Ballif, Bryan A, Botten, Jason

“…We report that the lymphocytic choriomeningitis virus (LCMV) matrix protein, which drives viral budding, is phosphorylated at serine 41 (S41). A recombinant…”
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Host-Driven Phosphorylation Appears to Regulate the Budding Activity of the Lassa Virus Matrix Protein by Ziegler, Christopher M, Eisenhauer, Philip, Manuelyan, Inessa, Weir, Marion E, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Lassa mammarenavirus (LASV) is an enveloped RNA virus that can cause Lassa fever, an acute hemorrhagic fever syndrome associated with significant morbidity and…”
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Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A by Schmoker, Anna M, Barritt, Samuel A, Weir, Marion E, Mann, Jacqueline E, Hogan, Tyler C, Ballif, Bryan A, Deming, Paula B

“…The cAMP-dependent protein kinase A (PKA) is a serine/threonine kinase involved in many fundamental cellular processes, including migration and proliferation…”
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A Map of the Arenavirus Nucleoprotein-Host Protein Interactome Reveals that Junín Virus Selectively Impairs the Antiviral Activity of Double-Stranded RNA-Activated Protein Kinase (PKR) by King, Benjamin R, Hershkowitz, Dylan, Eisenhauer, Philip L, Weir, Marion E, Ziegler, Christopher M, Russo, Joanne, Bruce, Emily A, Ballif, Bryan A, Botten, Jason

“…Arenaviruses are enveloped negative-strand RNA viruses that cause significant human disease. These viruses encode only four proteins to accomplish the viral…”
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A Proteomics Survey of Junín Virus Interactions with Human Proteins Reveals Host Factors Required for Arenavirus Replication by Ziegler, Christopher M, Eisenhauer, Philip, Kelly, Jamie A, Dang, Loan N, Beganovic, Vedran, Bruce, Emily A, King, Benjamin R, Shirley, David J, Weir, Marion E, Ballif, Bryan A, Botten, Jason

“…Arenaviruses are negative-strand, enveloped RNA viruses that cause significant human disease. In particular, Junín mammarenavirus (JUNV) is the etiologic agent…”
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FYN and ABL Regulate the Interaction Networks of the DCBLD Receptor Family by Schmoker, Anna M., Weinert, Jaye L., Markwood, Jacob M., Albretsen, Kathryn S., Lunde, Michelle L., Weir, Marion E., Ebert, Alicia M., Hinkle, Karen L., Ballif, Bryan A.

“…The FYN- and ABL-regulated interactomes of DCBLD proteins have been determined using quantitative mass spectrometry-based proteomics. FYN and ABL drove the…”
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Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2 by Schmoker, Anna M, Weinert, Jaye L, Kellett, Kyle J, Johnson, Hannah E, Joy, Ryan M, Weir, Marion E, Ebert, Alicia M, Ballif, Bryan A

“…Discoidin, CUB, and LCCL domain containing 2 (DCBLD2) is a neuropilin-like transmembrane scaffolding receptor with known and anticipated roles in vascular…”
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Fyn‐dependent phosphorylation of PlexinA1 and PlexinA2 at conserved tyrosines is essential for zebrafish eye development by St. Clair, Riley M., Emerson, Sarah E., D'Elia, Kristen P., Weir, Marion E., Schmoker, Anna M., Ebert, Alicia M., Ballif, Bryan A.

“…Plexins (Plxns) are semaphorin (Sema) receptors that play important signaling roles, particularly in the developing nervous system and vasculature. Sema‐Plxn…”
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Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain‐binding capacity by Weir, Marion E., Mann, Jacqueline E., Corwin, Thomas, Fulton, Zachary W., Hao, Jennifer M., Maniscalco, Jeanine F., Kenney, Marie C., Roman Roque, Kristal M., Chapdelaine, Elizabeth F., Stelzl, Ulrich, Deming, Paula B., Ballif, Bryan A., Hinkle, Karen L.

“…Src family tyrosine kinases (SFKs) are critical players in normal and aberrant biological processes. While phosphorylation importantly regulates SFKs at two…”
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Fyn Regulates Cyclic‐AMP Dependent Protein Kinase A Binding Interactions by Barritt, Samuel A, Weir, Marion E, Ballif, Bryan A, Deming, Paula B

“…Abstract only Cyclic‐AMP dependent protein kinase A (PKA) and Src family kinases (SFKs) are important for signal transduction in a multitude of cellular…”
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Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH 2 domain‐binding capacity by Weir, Marion E., Mann, Jacqueline E., Corwin, Thomas, Fulton, Zachary W., Hao, Jennifer M., Maniscalco, Jeanine F., Kenney, Marie C., Roman Roque, Kristal M., Chapdelaine, Elizabeth F., Stelzl, Ulrich, Deming, Paula B., Ballif, Bryan A., Hinkle, Karen L.

“…Src family tyrosine kinases ( SFK s) are critical players in normal and aberrant biological processes. While phosphorylation importantly regulates SFK s at two…”
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FYN and ABL Regulate the Interaction Networks of the DCBLD Receptor Family by Schmoker, Anna M, Weinert, Jaye L, Markwood, Jacob M, Albretsen, Kathryn S, Lunde, Michelle L, Weir, Marion E, Ebert, Alicia M, Hinkle, Karen L, Ballif, Bryan A

“…The Discoidin, CUB, and LCCL domain-containing protein (DCBLD) family consists of two type-I transmembrane scaffolding receptors, DCBLD1 and DCBLD2, which play…”
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Novel mechanisms governing autoregulation of the SRC family kinase FYN and its crosstalk with protein kinase A by Weir, Marion E

“…Phosphorylation is a post-translational modification important for regulating protein activity and protein binding capacity. It is used in many different…”
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