Search Results - "Weir, M R."

An alarmingly high prevalence of diabetic nephropathy in Asian type 2 diabetic patients: the MicroAlbuminuria Prevalence (MAP) Study by WU, A. Y. T, KONG, N. C. T, DE LEON, F. A, PAN, C. Y, TAI, T. Y, YEUNG, V. T. F, YOO, S. J, ROUILLON, A, WEIR, M. R

“…Microalbuminuria represents the earliest clinical evidence of diabetic nephropathy and is a marker of increased cardiovascular morbidity and mortality. Its…”
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Mammalian Target of Rapamycin Inhibitor Dyslipidemia in Kidney Transplant Recipients by Kasiske, B. L., de Mattos, A., Flechner, S. M., Gallon, L., Meier‐Kriesche, H.‐U., Weir, M. R., Wilkinson, A.

“…The incidence, pathogenesis, consequences and treatment of mammalian target of rapamycin (mTOR) inhibitor dyslipidemia are not well described. We conducted a…”
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Association of Serum Uric Acid With Graft Survival After Kidney Transplantation: A Time‐Varying Analysis by Haririan, A., Metireddy, M., Cangro, C., Nogueira, J. M., Rasetto, F., Cooper, M., Klassen, D. K., Weir, M. R.

“…The association of serum uric acid (UA) with kidney transplant outcomes is uncertain. We examined the predictive value of UA during the first year…”
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Risk for posttransplant diabetes mellitus with current immunosuppressive medications by Weir, Matthew R., Fink, Jeffrey C.

“…With improvements in the practice of transplantation and the introduction of new immunosuppressive medications, there has been a substantial increase in 1-year…”
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Targeting mechanisms of hypertensive vascular disease with dual calcium channel and renin-angiotensin system blockade by WEIR, M. R

“…Patients with hypertension, particularly those with diabetes mellitus, are at heightened risk for cardiovascular and renal disease. Accumulated evidence…”
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The Detrimental Effect of Poor Early Graft Function After Laparoscopic Live Donor Nephrectomy on Graft Outcomes by Nogueira, J. M., Haririan, A., Jacobs, S. C., Weir, M. R., Hurley, H. A., Al‐Qudah, H. S., Phelan, M., Drachenberg, C. B., Bartlett, S. T., Cooper, M.

“…We undertook this study to assess the rate of poor early graft function (EGF) after laparoscopic live donor nephrectomy (lapNx) and to determine whether poor…”
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How early should blood pressure control be achieved for optimal cardiovascular outcomes? by Weir, M R, Zappe, D, Orloski, L A, Sowers, J R

“…As a consequence of the aging population and the increasing prevalence rates for conditions such as type 2 diabetes and chronic kidney disease (CKD),…”
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Can the Early Elimination of Calcineurin Inhibitors Result in Clinical Benefits? by Weir, M.R

“…Abstract Ideally, every kidney should serve its owner for his or her remaining life expectancy. Current approaches with immunosuppression have steadily reduced…”
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Efficacy, safety and tolerability of aliskiren, a direct renin inhibitor, in women with hypertension: a pooled analysis of eight studies by Gradman, A H, Weir, M R, Wright, M, Bush, C A, Keefe, D L

“…Hypertension is a major risk factor for cardiovascular disease, which is the leading cause of mortality in women in developed countries. This pooled analysis…”
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Early Withdrawal of Calcineurin Inhibitors and Rescue Immunosuppression with Sirolimus‐Based Therapy in Renal Transplant Recipients with Moderate to Severe Renal Dysfunction by Wali, R. K., Mohanlal, V., Ramos, E., Blahut, S., Drachenberg, C., Papadimitriou, J., Dinits, M., Joshi, A., Philosophe, B., Foster, C., Cangro, C., Nogueira, J., Cooper, M., Bartlett, S. T., Weir, M. R.

“…Mammalian Target‐of‐Rapamycin inhibitors (mTOR inhibitors) can be used to replace the calcineurin inhibitors (CNIs) to prevent progression in chronic kidney…”
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Histological Evolution of BK Virus–Associated Nephropathy: Importance of Integrating Clinical and Pathological Findings by Drachenberg, C. B., Papadimitriou, J. C., Chaudhry, M. R., Ugarte, R., Mavanur, M., Thomas, B., Cangro, C., Costa, N., Ramos, E., Weir, M. R., Haririan, A.

“…Long‐term clinicopathological studies of BK‐associated nephropathy (PyVAN) are not available. We studied 206 biopsies (71 patients), followed 3.09 ± 1.46 years…”
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Islet cell damage associated with tacrolimus and cyclosporine : Morphological features in pancreas allograft biopsies and clinical correlation by DRACHENBERG, C. B, KLASSEN, D. K, WEIR, M. R, WILAND, A, FINK, J. C, BARTLETT, S. T, CANGRO, C. B, BLAHUT, S, PAPADIMITRIOU, J. C

“…The introduction of the potent immunosuppressive drugs tacrolimus (FK) and cyclosporine (CSA) has markedly improved the outcome of solid organ transplantation…”
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Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib by KONSTAM, Marvin A, WEIR, Matthew R, REICIN, Alise, SHAPIRO, Deborah, SPERLING, Rhoda S, BARR, Eliav, GERTZ, Barry J

“…In comparing aspirin, nonselective nonsteroidal antiinflammatory agents (NSAIDs), and cyclooxygenase (COX)-2 inhibitors, variation in platelet inhibitory…”
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Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy by Bakris, George L., Weir, Matthew R., Dequattro, Vincent, McMahon, F. Gilbert

“…Effects of an ACE inhibitor/calcium antagonist combination on proteinuria in diabetic nephropathy. The degree of proteinuria in patients with diabetes…”
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A novel approach to the treatment of chronic allograft nephropathy by WEIR, M. R, ANDERSON, L, LIM, J. Y, BARTLETT, S. T, FINK, J. C, GABREGIORGISH, K, SCHWEITZER, E. J, HOEHN-SARIC, E, KLASSEN, D. K, CANGRO, C. B, JOHNSON, L. B, KUO, P. C

“…Progressive deterioration of renal function in kidney transplant recipients is the leading cause of graft failure. Both nonimmunologic and immunologic…”
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Optimizing Early De Novo Immunosuppression With Sirolimus by Weir, M.R

“…Abstract In the past, renal transplant deterioration was approached as a problem of “chronic rejection,” which implied that deterioration of kidney function…”
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Optimizing Immunosuppression With Sirolimus in the First Year Posttransplantation: Experience in the United States by Weir, M.R, Wali, R.K

“…Abstract Early and late kidney graft survival has improved considerably due to advances in clinical care, particularly immunosuppression. Many of the kidney…”
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A comparison of recipient renal outcomes with laparoscopic versus open live donor nephrectomy by NOGUEIRA, J. M, CANGRO, C. B, PHILOSOPHE, B, BARTLETT, S. T, WEIR, M. R, FINK, J. C, SCHWEITZER, E, WILAND, A, KLASSEN, D. K, GARDNER, J, FLOWERS, J, JACOBS, S, CHO, E

“…Laparoscopic donor nephrectomy (laparoNx) has the potential to increase living kidney donation rates by reducing the pain and suffering of the donor. However,…”
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Human polyoma virus in renal allograft biopsies: Morphological findings and correlation with urine cytology by Drachenberg, Cinthia B, Beskow, Christian O, Cangro, Charles B, Bourquin, Patricia M, Simsir, Aylin, Fink, Jeffrey, Weir, Matthew R, Klassen, David K, Bartlett, Stephen T, Papadimitriou, John C

“…Human polyoma virus (PV) interstitial nephritis occurs in immunosuppressed patients after reactivation of latent virus in renal epithelium. Currently, there is…”
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Improved outcome of polyoma virus allograft nephropathy with early biopsy by Drachenberg, C.B, Papadimitriou, J.C, Wali, R, Nogueira, J, Mendley, S, Hirsch, H.H, Cangro, C.B, Klassen, D.K, Weir, M.R, Bartlett, S.T, Ramos, E

“…Polyoma virus allograft nephropathy often results in accelerated graft loss despite reduction of immunosuppression and/or treatment with antiviral agents…”
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